Advanced Pharmacology - Midterm
A 42-year antique man affords to you for observe-up treatment of a furuncle. He came in 3
days in advance and the place turned into 1.5 cm in length. At that time, he become afebrile
and with out ache, redness, or swelling. He became despatched domestic with commands to
apply a warm compress and became no longer given antibiotics. When have to a furuncle be
dealt with with systemic antibiotics?
A. If the area is painful
b. If the vicinity is red, along with the encircling tissues
c. Patient is febrile
d. All of above - ANS-d. All of above
A medicine overview of an aged person's medicines entails:
a. Asking the affected person to deliver a listing of cutting-edge prescription medications to
the visit.
B. Having the patient deliver all their prescription, over-the-counter, and herbal medicinal
drugs to the visit.
C. Asking what other carriers are writing prescriptions for them.
D. All of the above. - ANS-d. All of the above.
A potentially existence-threatening negative reaction to ACE-Is is angioedema. Which of the
following statements true about this damaging reaction?
A. Swelling of the tongue and hoarseness are the maximum commonplace signs.
B. It seems to be associated with the decrease in aldosterone production.
C. Presence of a dry, hacking cough shows a excessive hazard for this unfavorable reaction.
D. Because it takes time to accumulate a blood level, it takes place after being on the drug
for approximately one week. - ANS-a. Swelling of tongue and hoarseness are the maximum
commonplace signs.
A stepwise method to the pharmacologic control of bronchial asthma:
a. Allows for every company to decide their personal method to the care of asthmatic
patients
b. Is used while asthma is intense and required every day steroids
c. Starts offevolved with figuring out the severity of allergies and assessing allergies
manipulate
d. Affords a framework for the control of severe asthmatics, but isn't useful while sufferers
have intermittent allergies - ANS-c. Begins with figuring out the severity of asthma and
assessing allergies control
Acamprosate - ANS-Decreases unsightly consequences as a consequence of abstinence
like dysphoria, anxiety, restlessness
ACE inhibitors - ANS-"PRIL" Captopril, Enalapril, Afosiopril
, Antihypertensive. Blocks ACE in lungs from changing angiotensin I to angiotensin II
(effective vasoconstrictor). Decreases BP, Decreased Aldosterone secretions, Sodium and
fluid loss.
Check BP before giving (hypotension)
*Orthostatic Hypotension
ACE-Is are the drug of desire in treating HTN in diabetic patient because they:
a. Improve insulin sensitivity
b. Improve renal hemodynamics
c. Reduce the production of angiotensin II
d. All of above - ANS-d. All of above
ACEIs in heart failure - ANS-can improve purposeful repute and prolong lifestyles
acute consequences of alcohol on the brain - ANS-despair of CNS feature and activation of
the reward circuit
Adverse outcomes of ACE inhibitors - ANS--Cough
-Hypotension in hypovolemic sufferers
-Acute renal failure
-Hyperkalemia
-Angioedema
-Contraindicated in pregnancy
adverse outcomes of ARBS - ANS-angioedema and renal failure
destructive consequences of Disulfiram (antabuse) - ANS-acetaldehyde syndrome: caused
by use of alcohol with remedy. Signs and symptoms: nausea, vomiting, palpitations,
headache, chest pain, hypotension, in excessive form can be life threatening. Alcoholics who
lack the willpower to stop ingesting should not get hold of this remedy.
Aliskiren (Tekturna) - ANS-Mechanism of Action: Renin inhibitor
Clinical Uses: HTN secondary to renal failure or diabetes.
Adverse consequences: dose based diarrhea
Notes: do no longer use in pregnant ladies
Amiodarone - ANS-Use: lengthy-time period remedy of ventricular traumatic inflammation
and recurrent hemodynamically unstable ventricular tachycardia. Given to transform atrial
traumatic inflammation to normal sinus rhythm and to keep ordinary sinus rhythm after
conversion
Adverse effects: hypothyroidism, hyperthyroidism, optic neuropathy, optic neuritis,
photosensitivity reactions
Anaphylactic shock is a:
a. Type I reaction, called on the spot hypersensitive reaction response
b. Type II reaction, referred to as cytotoxic hypersensitive reaction response
c. Type III response, known as immune complex hypersensitive reaction
A 42-year antique man affords to you for observe-up treatment of a furuncle. He came in 3
days in advance and the place turned into 1.5 cm in length. At that time, he become afebrile
and with out ache, redness, or swelling. He became despatched domestic with commands to
apply a warm compress and became no longer given antibiotics. When have to a furuncle be
dealt with with systemic antibiotics?
A. If the area is painful
b. If the vicinity is red, along with the encircling tissues
c. Patient is febrile
d. All of above - ANS-d. All of above
A medicine overview of an aged person's medicines entails:
a. Asking the affected person to deliver a listing of cutting-edge prescription medications to
the visit.
B. Having the patient deliver all their prescription, over-the-counter, and herbal medicinal
drugs to the visit.
C. Asking what other carriers are writing prescriptions for them.
D. All of the above. - ANS-d. All of the above.
A potentially existence-threatening negative reaction to ACE-Is is angioedema. Which of the
following statements true about this damaging reaction?
A. Swelling of the tongue and hoarseness are the maximum commonplace signs.
B. It seems to be associated with the decrease in aldosterone production.
C. Presence of a dry, hacking cough shows a excessive hazard for this unfavorable reaction.
D. Because it takes time to accumulate a blood level, it takes place after being on the drug
for approximately one week. - ANS-a. Swelling of tongue and hoarseness are the maximum
commonplace signs.
A stepwise method to the pharmacologic control of bronchial asthma:
a. Allows for every company to decide their personal method to the care of asthmatic
patients
b. Is used while asthma is intense and required every day steroids
c. Starts offevolved with figuring out the severity of allergies and assessing allergies
manipulate
d. Affords a framework for the control of severe asthmatics, but isn't useful while sufferers
have intermittent allergies - ANS-c. Begins with figuring out the severity of asthma and
assessing allergies control
Acamprosate - ANS-Decreases unsightly consequences as a consequence of abstinence
like dysphoria, anxiety, restlessness
ACE inhibitors - ANS-"PRIL" Captopril, Enalapril, Afosiopril
, Antihypertensive. Blocks ACE in lungs from changing angiotensin I to angiotensin II
(effective vasoconstrictor). Decreases BP, Decreased Aldosterone secretions, Sodium and
fluid loss.
Check BP before giving (hypotension)
*Orthostatic Hypotension
ACE-Is are the drug of desire in treating HTN in diabetic patient because they:
a. Improve insulin sensitivity
b. Improve renal hemodynamics
c. Reduce the production of angiotensin II
d. All of above - ANS-d. All of above
ACEIs in heart failure - ANS-can improve purposeful repute and prolong lifestyles
acute consequences of alcohol on the brain - ANS-despair of CNS feature and activation of
the reward circuit
Adverse outcomes of ACE inhibitors - ANS--Cough
-Hypotension in hypovolemic sufferers
-Acute renal failure
-Hyperkalemia
-Angioedema
-Contraindicated in pregnancy
adverse outcomes of ARBS - ANS-angioedema and renal failure
destructive consequences of Disulfiram (antabuse) - ANS-acetaldehyde syndrome: caused
by use of alcohol with remedy. Signs and symptoms: nausea, vomiting, palpitations,
headache, chest pain, hypotension, in excessive form can be life threatening. Alcoholics who
lack the willpower to stop ingesting should not get hold of this remedy.
Aliskiren (Tekturna) - ANS-Mechanism of Action: Renin inhibitor
Clinical Uses: HTN secondary to renal failure or diabetes.
Adverse consequences: dose based diarrhea
Notes: do no longer use in pregnant ladies
Amiodarone - ANS-Use: lengthy-time period remedy of ventricular traumatic inflammation
and recurrent hemodynamically unstable ventricular tachycardia. Given to transform atrial
traumatic inflammation to normal sinus rhythm and to keep ordinary sinus rhythm after
conversion
Adverse effects: hypothyroidism, hyperthyroidism, optic neuropathy, optic neuritis,
photosensitivity reactions
Anaphylactic shock is a:
a. Type I reaction, called on the spot hypersensitive reaction response
b. Type II reaction, referred to as cytotoxic hypersensitive reaction response
c. Type III response, known as immune complex hypersensitive reaction
