3rd Edition by M. Linda Workman & LaCharity
,Chaptero01:oDrugoRegulation,oActions,oandoResponses
Workmano&oLaCharity:oUnderstandingoPharmacology:oEssentialsoforoMedicationoSafety,o3rdoEdition
MULTIPLEoCHOICEoBASICo CONC
EPTS
1. Whichohealthocareoprofessionalohasotheomajororesponsibilityoforodispensingoprescribedo
drugsounderotheodirectionoofoaopharmacist?
a. Physician
b Nurseopractitioner
.
c. Licensedonurse
d Pharmacyotechnician
.
ANS:oo D
Theophysicianoandonurseopractitionerohaveotheomajororesponsibilityoforoprescribingodrugs,onoto dispens
ingothem.oTheolicensedonurseohasotheoprimaryoresponsibilityoforoadministeringodrugs,o althoughoundero
someocircumstancesoaolicensedonurseomayodispenseoprescribedodrugsobutothisoisonoto hisooroheromajoror
esponsibilityoinodrugotherapy.oTheopharmacyotechnicianohasotheomajoro responsibilityoofodispensingopr
escribedodrugsounderotheodirectionoofoaolicensedopharmacist.
DIF: CognitiveoLevel:oRemembering REF: p.o3
2. Whichotermodescribesotheoeffectoofoaodrugothatoimprovesobodyofunction?
a. Sideoeffect
b Intendedoaction
.
c. Adverseoreaction
d Idiosyncraticoresponse
.
ANS:oo B
Theopurposeoofodrugotherapyoisotootakeoaodrugotooprevent,oreduce,oorocorrectoaohealthoproblem.oThis
responseoisoanyodrug’sointendedoactionoalsooknownoasoaotherapeuticoresponse.
DIF: CognitiveoLevel:oRemembering REF: p.o3
3. Whichotypeoofodrugonameoiso“owned”obyotheocompanyothatomanufacturesoit?
a. Genericoname
b Chemicaloname
,.
c. Categoryoname
d Tradeoname
.
ANS:oo D
Theochemicalonameoisoaodrug’soexactochemicalocomposition.oTheogenericonameoisotheonameoassignedotoo t
heodrugobyotheoU.S.oAdoptedoNamesoCounciloandoisonotoownedobyoanyone.oTheocategoryonameoreferso toot
heotypeoofodrugo(whatoitodoesoorowhatoitoisousedofor)oandoisonotoanoactualodrugoname.oTheotradeo nameo(br
andoname)oisotheonameoprovidedoandoownedobyoaospecificodrug’somanufacturer.
DIF: CognitiveoLevel:oRemembering REF: p.o4
4. Whichodrugoorodrugoclassoisoao“highoalert”odrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:oo B
Aohighoalertodrugoisooneoinowhichoharmoisolikelyotooresultoifogivenoatotheowrongodose,otootheowrongo patie
nt,ooronotogivenotootheocorrectopatient.oDrugsoclassifiedoasohighoalertodrugsoincludeopotassium,o narcoticso
(opioids),oinsulin,ocancerochemotherapyodrugs,oandoheparino(oroanyodrugothatostronglyo affectsobloodocl
otting).oPenicillin,oNSAIDs,oandocalciumoareonotoconsideredohighoalertodrugs.
DIF: CognitiveoLevel:oRemembering REF: p.o4
5. Whatoisotheotermoforoaodrugothatohasotheosameoactionoasoaonaturallyooccurringobodyo h
ormoneooroenzyme?
a. Agonist
b Blockingoagent
.
c. Chemical
d Duplicator
.
ANS:oo A
Aodrugoagonistoisoanoextrinsicodrugothatoactivatesotheoreceptorositesoofoaocelloandomimicsotheoactionsoofo natu
rallyooccurringobodyosubstanceso(intrinsicodrugs).oAoblockingoagentoisoaodrug
, antagonist.oAochemicalowouldonotonecessarilyobeoaodrugoatoall.oAoduplicatoroisonotoaopharmacologicoterm.o
DIF: CognitiveoLevel:oRemembering REF: pp.o6-7
6. Whichotermodescribesohowotheobodyoaffectsodrugoactivity?
a. Drugopotency
b Pharmacodynamics
.
c. Therapeuticoeffect
d Pharmacokinetics
.
ANS:oo D
Theotermopharmacokineticsorefersotoodrugometabolismoandohowotheobodyochangesoaodrug.o Pharmacod
ynamicsorefersotoohowoaodrugoworksotoochangeobodyofunction.oDrugopotencyorefersotoohowo stronglyoorot
oowhatodegreeoaodrugoexertsoitsoeffects.oTheotherapeuticoeffectoisocloserotoo pharmacodynamics,omeaning
ohowoaodrugoworksotoochangeobodyofunction.
DIF: CognitiveoLevel:oRemembering REF: p.o10
7. InotheoUnitedoStates,owhichogroupoisoresponsibleoforoenforcingoestablishedostandardsoforo
drugomanufacturing?
a. U.S.oPharmacopeia
b NationaloInstitutesoofoHealth
.
c. FoodoandoDrugoAdministration
d AssociationoofoPharmaceuticaloManufacturers
.
ANS:oo C
TheostandardsoforodrugomanufactureoareoestablishedobyotheoU.S.oPharmacopeia.oTheseo standardsoareo e
nforcedo byo theo Foodo ando Drugo Administration.o Neithero theo Nationalo Instituteso ofo Healtho noro theo As
sociationoofoPharmaceuticaloManufacturersohasoanyoauthorityotooenforceodrugostandards.
DIF:oooo CognitiveoLevel:oRememberingooooooooo REF:ooo p.o5
8. Whichofactoroisoaomajorodisadvantageoofotheotransdermalodrugodeliveryoroute?
a. Onlyoaoprescriberocanoadministerodrugsobyotheotransdermaloroute.
b Transdermalodrugsomustobeosterileoratherothanoclean.
.
c. Firstopassodrugolossobyothisorouteoisotheomostoextensive.
d Drugoabsorptionoisodependentoonoadequateocirculation.