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NURS 5315 UTA Exam 2 (2025) Newest Questions and
Answers (Verified Answers)
HIV EIA (3rd generation immunoassay) - (answers)can use urine, saliva, or serum
(most accurate), need to wait until 12 weeks post exposure to see antibodies,
>99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell - (answers)Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory process.
Histamine - (answers)Causes vasodilation, increases vascular permeability,
increases blood flow to the site of injury- causes erythema and swelling.
Cytokines - (answers)Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can be pro-inflammatory
or anti-inflammatory. Can react quickly or be more delayed.
Leukotrines - (answers)Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
, 2
Prostaglandins - (answers)Released when mast cells degranulate, are produced by
the arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury,
pain, and fever.
Chemotactic factors - (answers)Biochemical substance that attracts leukocyte to
the site of inflammation
Neutrophils - (answers)Predominant leukocyte at work during the early stages of
acute inflammation
Monocytes - (answers)Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4 cell which triggers T-cell immunity
and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function - (answers)Causes fever, activates phagocytes &
lymphocytes and also increases the release of IL6a
Cytokine IL6 function - (answers)Stimulates production of acute phase reactants
and promotes growth and stimulation of RBCs
Cytokine TNF function - (answers)Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle wasting, induces thrombosis
, 3
Cytokine growth factor function - (answers)Promotes production and maturation
of neutrophils
Complement - (answers)Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast cell degranulation, chemotaxis, and
opsonization.
Kinin - (answers)Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
Coagulation cascade - (answers)Factor XII activates kinin. Function is to form
fibrin mesh to stop bleeding and trap micro organisms.
COX1 - (answers)Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte balance
COX2 - (answers)Prostaglandin of arachidonic pathway. Responsible for pain,
fever, renal protection, tissue repair, reproduction development.
COX2 inhibitors- clinical implications - (answers)Protect gastric mucosa- prevent
ulcers and bleeding. Removed from market r/t cardiac events except for Celebrex.
Can impair renal function , monitor labs.
Arachidonic pathway purpose - (answers)Synthesis of prostaglandins
NURS 5315 UTA Exam 2 (2025) Newest Questions and
Answers (Verified Answers)
HIV EIA (3rd generation immunoassay) - (answers)can use urine, saliva, or serum
(most accurate), need to wait until 12 weeks post exposure to see antibodies,
>99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell - (answers)Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory process.
Histamine - (answers)Causes vasodilation, increases vascular permeability,
increases blood flow to the site of injury- causes erythema and swelling.
Cytokines - (answers)Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can be pro-inflammatory
or anti-inflammatory. Can react quickly or be more delayed.
Leukotrines - (answers)Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
, 2
Prostaglandins - (answers)Released when mast cells degranulate, are produced by
the arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury,
pain, and fever.
Chemotactic factors - (answers)Biochemical substance that attracts leukocyte to
the site of inflammation
Neutrophils - (answers)Predominant leukocyte at work during the early stages of
acute inflammation
Monocytes - (answers)Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4 cell which triggers T-cell immunity
and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function - (answers)Causes fever, activates phagocytes &
lymphocytes and also increases the release of IL6a
Cytokine IL6 function - (answers)Stimulates production of acute phase reactants
and promotes growth and stimulation of RBCs
Cytokine TNF function - (answers)Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle wasting, induces thrombosis
, 3
Cytokine growth factor function - (answers)Promotes production and maturation
of neutrophils
Complement - (answers)Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast cell degranulation, chemotaxis, and
opsonization.
Kinin - (answers)Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
Coagulation cascade - (answers)Factor XII activates kinin. Function is to form
fibrin mesh to stop bleeding and trap micro organisms.
COX1 - (answers)Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte balance
COX2 - (answers)Prostaglandin of arachidonic pathway. Responsible for pain,
fever, renal protection, tissue repair, reproduction development.
COX2 inhibitors- clinical implications - (answers)Protect gastric mucosa- prevent
ulcers and bleeding. Removed from market r/t cardiac events except for Celebrex.
Can impair renal function , monitor labs.
Arachidonic pathway purpose - (answers)Synthesis of prostaglandins
