NUR 529 - Exam 1 (Innate and Adaptive
Immunity) Questions And Answers |Latest
2025 | Guaranteed Pass.
Time of response for innate immunity - Answer✔immediate (minutes/hours)
time of response for adaptive immunity - Answer✔depends on exposure (1st - delayed, 2nd -
immediate d/t production of Abs)
features of innate immunity - Answer✔diversity limited to classes or groups of microbes,
nonspecific microbe recognition, response similar with each exposure
features of adaptive immunity - Answer✔very large diversity with specific response for each Ag
(Ag/Ab complexes), has immunologic memory so more rapid and efficient with subsequent
exposure
defense method of innate immunity - Answer✔epithelium, phagocytes (monocytes,
macrophages, neutrophils), NK cells, DCs (dendritic cells)
defense method of adaptive immunity - Answer✔T and B lymphocytes, macrophages, DCs
(dendritic cells), NK cells
molecular components of innate immunity - Answer✔cytokines, complement proteins, acute-
phase proteins, soluble mediators
molecular components of adaptive immunity - Answer✔antibodies, cytokines, complement
system
dendritic cells (DCs) - Answer✔-engulf and degrade microbes and display them to T cells
-found in the skin, genital tract, lymph nodes, spleen, thymus, and blood
cytokines - Answer✔Chemicals released by the immune system communicate with the brain
(not cell specific)
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chemokines - Answer✔subset of cytokines that are responsible for directing the migration of
leukocytes to both areas of injury and locations where immune responses have been activated,
such as lymph nodes, spleen, Peyer patches, and tonsils
adaptive immunity 2 types - Answer✔1) humoral immunity - mediated by B lymphocytes,
principal defense against extracellular microbes and their toxins
2) cell-mediated immunity - mediated by cytotoxic T lymphocytes and functions in the
elimination of intracellular pathogens (eg viruses)
colony stimulating factors (CSFs) - Answer✔stimulate growth and differentiation of immature
leukocytes in bone marrow
what features of epithelial tissue makes it effective in innate immunity - Answer✔sheets of
tightly packed epithelial cells
destruction of invading antimicrobial enzymes, proteins, and peptides
goblet cells in GI tract secrete mucin (turns to mucus when hydrated)
cilia in respiratory tract moves mucus up so it can be coughed or sneezed
neutrophils - Answer✔55% of WBCs; phagocytic cells
early responders in innate immunity
rare in tissues and body cavities and lay predominantly dormant in blood and bone marrow
until needed
eosinophils - Answer✔1-4% of WBCs
do not ingest cellular debris, ingest Ag-Ab complexes and viruses
become active in parasitic infections and allergic responses
basophils - Answer✔<1% of WBCs
contain granules that release histamine and proteolytic enzymes
play a role in allergy and parasitic infections, although not completely understood
monocytes - Answer✔3-7% of WBCs
largest of WBCs
released from bone marrow in bloodstream where they migrate into tissues and mature into
macrophages and dendritic cells so they can participate in inflammatory response and
phagocytize foreign substances and cellular debris
long life span
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