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NURS 5315 Advanced Pathophysiology 2024/2025 Exam Questions and Corresponding Answers with Surety of 100% Pass Mark
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NURS 5315 Advanced Pathophysiology 2024/2025 Exam Questions and Corresponding Answers with Surety of 100% Pass Mark Ovarian cancer site of metastasis? -

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  • February 24, 2025
  • 24
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • nurs 5315 advanced pathophysiology

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  • Advanced pathophysiology
  • Advanced pathophysiology

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NURS 5315 Advanced Pathophysiology
2024/2025 Exam Questions and
Corresponding Answers with Surety of
100% Pass Mark


Ovarian cancer site of metastasis? - 🧠ANSWER ✔✔Peritoneal surfaces,

omentum (fold of peritoneum connecting the stomach with other abdominal

organs), *liver*

The increased NADH/NAD+ ratio in the liver from ethanol causes: -

🧠ANSWER ✔✔1. Pyruvate --> lactic acid, causing lactic acidosis

2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to

hypoglycemia

3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines

with fatty acids to form triglycerides in the liver, known as hepatosteatosis

4. Decreases citric acid cycle production of NADH and leads to using

Acetyl-CoA for ketogenesis and lipogenesis

What can Reactive Oxygen Species cause? - 🧠ANSWER ✔✔Heart

disease, Alzheimers, Parkinsons, Amyotrophic Lateral Sclerosis (ALS), CV

disease, HTN, HLD, DM, ischemic heart disease, HF, OSA. Lipid



COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY 1
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,perioxidation, damage proteins, fragment DNA, less *protein synthesis*,

chromatin destruction, damage mitochondria

What is the body's defense against ROS? - 🧠ANSWER ✔✔Antioxidants

(Vitamin E, Vitamin C, cysteine, glutathione, albumin, ceruloplasmin,

transferrin)

How are free radicals produced? - 🧠ANSWER ✔✔1. Normal cellular

respiration

2. Absorption of extreme energy sources (radiation, UV light)

3. Metabolism of exogenous chemicals, drugs, and pesticides

4. Transition of metals

5. Nitric oxide acting like a chemical mediator and a free radical

action potential - 🧠ANSWER ✔✔Process of conducting an impulse.

Activates the neuron --> the neuron depolarizes --> then repolarizes

Threshold potential - 🧠ANSWER ✔✔Point at which depolarization must

reach in order to initiate an action potential

Hypokalemia and action potentials - 🧠ANSWER ✔✔HYPERpolarized

(more negative, ex. -100). Less excitable. Decreased neuromuscular

excitability: weakness, smooth muscle atony, paresthesia, cardiac

dysrhythmias



COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY 2
STATEMENT. ALL RIGHTS RESERVE

, Hyperkalemia and action potentials - 🧠ANSWER ✔✔HYPOpolarized (more

positive, ex: closer to 0). More excitable. Peaked T waves.

When resting membrane potential=threshold potential, it is BAD = cardiac

standstill, paresthesia, paralysis

Hypocalcemia and action potentials - 🧠ANSWER ✔✔Increased

permeability to Na+. More excitable. Tetany, hyperreflexia, circumoral

paresthesia, seizures, dysrhythmias.

Hypercalcemia and action potentials - 🧠ANSWER ✔✔Decreased

permeability to Na+. Less excitable. Weakness, hyporeflexia, fatigue,

lethargy, confusion, encephalopathy, depressed T waves

Atrophy - 🧠ANSWER ✔✔Occurs as a result of decrease in work load,

pressure, use, blood supply, nutrition, hormonal stimulation, or nervous

stimulation. Once the cell has decreased in size, it has now compensated

for decreased blood supply, nerve supply, nutrient supply, hormonal

supply, and has achieved new homeostasis. Cells are alive but have

diminished function and may lead to cellular death.

Atrophy examples - 🧠ANSWER ✔✔Physiologic atrophy- shrinking of the

thymus gland during childhood.

Disuse atrophy- someone that ends up being paralyzed



COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY 3
STATEMENT. ALL RIGHTS RESERVE

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