,
,
,
,
,
,
,Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
1. Ischemia and other toxic injuries increase the accumulation of
intracellular calcium as a result of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
2. The patient is found to have liver disease, resulting in the removal of a
lobe of his liver. Adaptation to the reduced size of the liver leads to
of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
3. A person eating peanuts starts choking and collapses. His airway obstruction
is partially cleared, but he remains hypoxic until he reaches the hospital. The
prolonged cell hypoxia caused a cerebral infarction and resulting
in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
4. Bacteria and viruses cause cell damage by , which is unique from
the intracellular damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
,Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
D) decreasing protein synthesis and function
5. The patient has a prolonged interruption in arterial blood flow to his left
j j j j j j j j j j j j j
kidney, causing hypoxic cell injury and the release of free radicals. Fre
j j j j j j j j j j j
e radicals damage cells by:
j j j j j
A) destroying phospholipids in the cell membrane. j j j j j j
B) altering the immune response of the cell.
j j j j j j j
C) disrupting calcium storage in the cell. j j j j j j
D) inactivation of enzymes and mitochondria. j j j j j
6. Injured cells have impaired flow of substances through the cell membran
j j j j j j j j j j
e as a result of:
j j j j j
A) increased fat load. j j j
B) altered permeability.j j
C) altered glucose utilization.
j j j
D) increased surface receptors. j j j
7. Reversible adaptive intracellular responses are initiated by:
j j j j j j j
A) stimulus overload. j j
B) genetic mutations. j j
C) chemical messengers. j j
D) mitochondrial DNA. j j
8. Injured cells become very swollen as a result of:
j j j j j j j j j
A) increased cell protein synthesis. j j j j
B) altered cell volume regulation.
j j j j
C) passive entry of potassium into the cell.
j j j j j j j
D) bleb formation in the plasma membrane.
j j j j j j
, Advanced Physiology and Pathophysiology Essentials for
j j j j j
Clinical Practice 2nd Edition Tkacs Test Bank j j j j j j
9. A diabetic patient has impaired sensation, circulation, and oxygenation of his fee
j j j j j j j j j j j
t. He steps on a piece of glass, the wound does not heal, and the area tissue beco
j j j j j j j j j j j j j j j j j
mes necrotic. The necrotic cell death is characterized by:
j j j j j j j j j
A) rapid apoptosis. j j
B) cellular rupture. j j
C) shrinkage and collapse. j j j
D) chronic inflammation. j j
10 A 99-year-old woman has experienced the decline of cell function associated
j j j j j j j j j j j
. with age. A group of theories of cellular aging focus on programmed:
j j j j j j j j j j j
A) changes with genetic influences. j j j j
B) elimination of cell receptor sites. j j j j j
C) insufficient telomerase enzyme. j j j
D) DNA mutation or faulty repair. j j j j j
11 An 89-year-old female patient has experienced significant decreases in her
j j j j j j j j j
. mobility and stamina during a 3- j j j j j
week hospital stay for the treatment of a femoral head fracture. Which
j j j j j j j j j j j j
of the following phenomena most likely accounts for the patients decr
j j j j j j j j j j
ease in muscle function that underlies her reduced mobility?
j j j j j j j j
D) Impaired muscle cell metabolism resulting from metaplasia j j j j j j j
E) Dysplasia as a consequence of inflammation during bone remodeling j j j j j j j j j
F) Disuse atrophy of muscle cells during a prolonged period of immobility
j j j j j j j j j j j
G) Ischemic atrophy resulting from vascular changes while on bedrest j j j j j j j j j
12 A 20-year-old college student has presented to her campus medical clinic for
j j j j j j j j j j j
.
a scheduled Papanicolaou (Pap) smear. The clinician who will inte
j j j j j j j j j
rpret the smear will examine cell samples for evidence of:
j j j j j j j j j
A) changes in cell shape, size, and organization. j j j j j j j
B) the presence of unexpected cell types.
j j j j j j
,
,
,
,
,
,Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
1. Ischemia and other toxic injuries increase the accumulation of
intracellular calcium as a result of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
2. The patient is found to have liver disease, resulting in the removal of a
lobe of his liver. Adaptation to the reduced size of the liver leads to
of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
3. A person eating peanuts starts choking and collapses. His airway obstruction
is partially cleared, but he remains hypoxic until he reaches the hospital. The
prolonged cell hypoxia caused a cerebral infarction and resulting
in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
4. Bacteria and viruses cause cell damage by , which is unique from
the intracellular damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
,Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
D) decreasing protein synthesis and function
5. The patient has a prolonged interruption in arterial blood flow to his left
j j j j j j j j j j j j j
kidney, causing hypoxic cell injury and the release of free radicals. Fre
j j j j j j j j j j j
e radicals damage cells by:
j j j j j
A) destroying phospholipids in the cell membrane. j j j j j j
B) altering the immune response of the cell.
j j j j j j j
C) disrupting calcium storage in the cell. j j j j j j
D) inactivation of enzymes and mitochondria. j j j j j
6. Injured cells have impaired flow of substances through the cell membran
j j j j j j j j j j
e as a result of:
j j j j j
A) increased fat load. j j j
B) altered permeability.j j
C) altered glucose utilization.
j j j
D) increased surface receptors. j j j
7. Reversible adaptive intracellular responses are initiated by:
j j j j j j j
A) stimulus overload. j j
B) genetic mutations. j j
C) chemical messengers. j j
D) mitochondrial DNA. j j
8. Injured cells become very swollen as a result of:
j j j j j j j j j
A) increased cell protein synthesis. j j j j
B) altered cell volume regulation.
j j j j
C) passive entry of potassium into the cell.
j j j j j j j
D) bleb formation in the plasma membrane.
j j j j j j
, Advanced Physiology and Pathophysiology Essentials for
j j j j j
Clinical Practice 2nd Edition Tkacs Test Bank j j j j j j
9. A diabetic patient has impaired sensation, circulation, and oxygenation of his fee
j j j j j j j j j j j
t. He steps on a piece of glass, the wound does not heal, and the area tissue beco
j j j j j j j j j j j j j j j j j
mes necrotic. The necrotic cell death is characterized by:
j j j j j j j j j
A) rapid apoptosis. j j
B) cellular rupture. j j
C) shrinkage and collapse. j j j
D) chronic inflammation. j j
10 A 99-year-old woman has experienced the decline of cell function associated
j j j j j j j j j j j
. with age. A group of theories of cellular aging focus on programmed:
j j j j j j j j j j j
A) changes with genetic influences. j j j j
B) elimination of cell receptor sites. j j j j j
C) insufficient telomerase enzyme. j j j
D) DNA mutation or faulty repair. j j j j j
11 An 89-year-old female patient has experienced significant decreases in her
j j j j j j j j j
. mobility and stamina during a 3- j j j j j
week hospital stay for the treatment of a femoral head fracture. Which
j j j j j j j j j j j j
of the following phenomena most likely accounts for the patients decr
j j j j j j j j j j
ease in muscle function that underlies her reduced mobility?
j j j j j j j j
D) Impaired muscle cell metabolism resulting from metaplasia j j j j j j j
E) Dysplasia as a consequence of inflammation during bone remodeling j j j j j j j j j
F) Disuse atrophy of muscle cells during a prolonged period of immobility
j j j j j j j j j j j
G) Ischemic atrophy resulting from vascular changes while on bedrest j j j j j j j j j
12 A 20-year-old college student has presented to her campus medical clinic for
j j j j j j j j j j j
.
a scheduled Papanicolaou (Pap) smear. The clinician who will inte
j j j j j j j j j
rpret the smear will examine cell samples for evidence of:
j j j j j j j j j
A) changes in cell shape, size, and organization. j j j j j j j
B) the presence of unexpected cell types.
j j j j j j
