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Exam 2: NU150/ NU 150 (Latest 2025/ 2026 Update) Pharmacology Guide| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Galen

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Exam 2: NU150/ NU 150 (Latest 2025/ 2026 Update) Pharmacology Guide| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Galen QUESTION antitubercular drugs Answer: Isoniazid (INH) Rifampin QUESTION antitubercular MOA Answer: anti tubercular drugs are bacteriostatic & bactericidal against the mycobacterium tuberculosis bacterium QUESTION Antitubercular indication Answer: treatment of TB QUESTION Antitubercular AR Answer: -hepatic failure -jaundice -skin eruptions -GI upset -hematologic changes (CBC) INH: peripheral neuropathy (b6 def) Rifampin: -reddish-orange discoloration of body fluids -vertigo QUESTION antitubercular NI & Pt teaching Answer: NI: -therapy for 9 mo - yr -monitor for compliance -monitor liver function pt teaching: -no alcohol -urine/body fluid discoloration -complete med course as Rx -supplement Vit b6 QUESTION antitubercular contraindications & Interactions Answer: CI: severe liver disease Interactions: INH: foods high in tyramine (aged cheese, cured meats, aged wine) may result in HTN, tachycardia, and palpitations Rifampin: oral contraceptives; oral DM meds both: anticoagulants QUESTION Antihistamine drugs Answer: 1st generation: diphenhydramine 2nd generation: loratadine QUESTION antihistamine MOA Answer: Block histamine receptors (H1) throughout body to prevent allergic reactions QUESTION Antihistamines indication Answer: -seasonal allergies -allergic rhinitis -allergic conjunctivitis -urticaria -allergic reaction to meds ** -motion sickness -Parkinson's symptoms: diphenhydramine -cough relief QUESTION antihistamines AR Answer: 1st gen: drowsiness, sedation, HOTN 2nd gen: less sedation & anticholinergic effects -thickening of bronchial secretions -restlessness (age extremes) -anticholinergic effects( constipation, dry mouth, urinary retention, blurred vision) QUESTION antihistamine NI & Pt edu Answer: NI: -diphenhydramine: PO/IM/IV -monitor pt response to therapy -monitor BP -assess bowel & urinary pattern -anticipate fall risk pt edu: -dont drive -increase fluids -neti-pot or humidifier -no ETOH; see MD if no improvement after 7-10 days loratadine: only take one a day; make take several days to take effect diphenhydramine: every 4-6 hrs

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Uploaded on
February 11, 2025
Number of pages
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Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

Subjects

  • antihistam

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Examl 2:l NU150/l NUl 150l (Latestl 2025/l
2026l Update)l Pharmacologyl Guide|l
Questionsl &l Answers|l Gradel A|l 100%l
Correctl (Verifiedl Solutions)-l Galen

Q:l antitubercularl drugs

Answer:
Isoniazidl (INH)
Rifampin




Q:l antitubercularl MOA

Answer:
antil tubercularl drugsl arel bacteriostaticl &l bactericidall againstl thel mycobacteriuml
tuberculosisl bacterium




Q:l Antitubercularl indication

Answer:
treatmentl ofl TB




Q:l Antitubercularl AR

Answer:
-hepaticl failure

,-jaundice
-skinl eruptions
-GIl upset
-hematologicl changesl (CBC)

INH:
peripherall neuropathyl (b6l def)

Rifampin:
-reddish-orangel discolorationl ofl bodyl fluids
-vertigo




Q:l antitubercularl NIl &l Ptl teaching

Answer:
NI:
-therapyl forl 9l mol -l yr
-monitorl forl compliancel
-monitorl liverl function

ptl teaching:
-nol alcoholl
-urine/bodyl fluidl discoloration
-completel medl coursel asl Rx
-supplementl Vitl b6




Q:l antitubercularl contraindicationsl &l Interactions

Answer:
CI:
severel liverl disease

Interactions:
INH:l foodsl highl inl tyraminel (agedl cheese,l curedl meats,l agedl wine)l mayl resultl inl
HTN,l tachycardia,l andl palpitations

,Rifampin:l orall contraceptives;l orall DMl meds

both:l anticoagulants




Q:l Antihistaminel drugs

Answer:
1stl generation:l diphenhydramine

2ndl generation:l loratadine




Q:l antihistaminel MOA

Answer:
Blockl histaminel receptorsl (H1)l throughoutl bodyl tol preventl allergicl reactions




Q:l Antihistaminesl indication

Answer:
-seasonall allergiesl
-allergicl rhinitis
-allergicl conjunctivitisl
-urticaria
-allergicl reactionl tol medsl **
-motionl sickness
-Parkinson'sl symptoms:l diphenhydramine
-coughl relief




Q:l antihistaminesl AR

, Answer:
1stl gen:l drowsiness,l sedation,l HOTN
2ndl gen:l lessl sedationl &l anticholinergicl effectsl

-thickeningl ofl bronchiall secretions
-restlessnessl (agel extremes)
-anticholinergicl effects(l constipation,l dryl mouth,l urinaryl retention,l blurredl vision)




Q:l antihistaminel NIl &l Ptl edu

Answer:
NI:
-diphenhydramine:l PO/IM/IV
-monitorl ptl responsel tol therapyl
-monitorl BP
-assessl bowell &l urinaryl pattern
-anticipatel falll riskl

ptl edu:
-dontl drive
-increasel fluids
-neti-potl orl humidifierl
-nol ETOH;l seel MDl ifl nol improvementl afterl 7-10l daysl

loratadine:l onlyl takel onel al day;l makel takel severall daysl tol takel effect

diphenhydramine:l everyl 4-6l hrs




Q:l antihistaminel CIl &l interactions

Answer:
CI:
1stl gen:l glaucoma;l pepticl ulcerl disease;l BPHl and/orl urinel retention;l acutel asthmal
attacks

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