2026l Update)l Pharmacologyl Guide|l
Questionsl &l Answers|l Gradel A|l 100%l
Correctl (Verifiedl Solutions)-l Galen
Q:l antitubercularl drugs
Answer:
Isoniazidl (INH)
Rifampin
Q:l antitubercularl MOA
Answer:
antil tubercularl drugsl arel bacteriostaticl &l bactericidall againstl thel mycobacteriuml
tuberculosisl bacterium
Q:l Antitubercularl indication
Answer:
treatmentl ofl TB
Q:l Antitubercularl AR
Answer:
-hepaticl failure
,-jaundice
-skinl eruptions
-GIl upset
-hematologicl changesl (CBC)
INH:
peripherall neuropathyl (b6l def)
Rifampin:
-reddish-orangel discolorationl ofl bodyl fluids
-vertigo
Q:l antitubercularl NIl &l Ptl teaching
Answer:
NI:
-therapyl forl 9l mol -l yr
-monitorl forl compliancel
-monitorl liverl function
ptl teaching:
-nol alcoholl
-urine/bodyl fluidl discoloration
-completel medl coursel asl Rx
-supplementl Vitl b6
Q:l antitubercularl contraindicationsl &l Interactions
Answer:
CI:
severel liverl disease
Interactions:
INH:l foodsl highl inl tyraminel (agedl cheese,l curedl meats,l agedl wine)l mayl resultl inl
HTN,l tachycardia,l andl palpitations
,Rifampin:l orall contraceptives;l orall DMl meds
both:l anticoagulants
Q:l Antihistaminel drugs
Answer:
1stl generation:l diphenhydramine
2ndl generation:l loratadine
Q:l antihistaminel MOA
Answer:
Blockl histaminel receptorsl (H1)l throughoutl bodyl tol preventl allergicl reactions
Q:l Antihistaminesl indication
Answer:
-seasonall allergiesl
-allergicl rhinitis
-allergicl conjunctivitisl
-urticaria
-allergicl reactionl tol medsl **
-motionl sickness
-Parkinson'sl symptoms:l diphenhydramine
-coughl relief
Q:l antihistaminesl AR
, Answer:
1stl gen:l drowsiness,l sedation,l HOTN
2ndl gen:l lessl sedationl &l anticholinergicl effectsl
-thickeningl ofl bronchiall secretions
-restlessnessl (agel extremes)
-anticholinergicl effects(l constipation,l dryl mouth,l urinaryl retention,l blurredl vision)
Q:l antihistaminel NIl &l Ptl edu
Answer:
NI:
-diphenhydramine:l PO/IM/IV
-monitorl ptl responsel tol therapyl
-monitorl BP
-assessl bowell &l urinaryl pattern
-anticipatel falll riskl
ptl edu:
-dontl drive
-increasel fluids
-neti-potl orl humidifierl
-nol ETOH;l seel MDl ifl nol improvementl afterl 7-10l daysl
loratadine:l onlyl takel onel al day;l makel takel severall daysl tol takel effect
diphenhydramine:l everyl 4-6l hrs
Q:l antihistaminel CIl &l interactions
Answer:
CI:
1stl gen:l glaucoma;l pepticl ulcerl disease;l BPHl and/orl urinel retention;l acutel asthmal
attacks