NR 565 - advanced pharmacology FINAL -
1. In which patient population is Metformin contraindi- C. Alcoholics
cated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
2. What lab value suggests metformin might be con- A. eGFR <30
traindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
3. What medication is contraindicated to treat diabetes if B. Thiazolidinediones
a patient already has a cardiac ejection fraction rate of
40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor
4. Sabrina is a 35-year-old female who presents with A. Methimazole
complaints of fatigue, anxiety, and palpitations. She
has a long history of obesity and reports that she is
happy that she has lost 23 pounds in the last 2 months.
She also reports that she has trouble sleeping and her
husband complains that she is keeping the house too
cold. Physical exam reveals slight tachycardia at 104
bpm and a slightly enlarged thyroid. Thyroid testing
, NR 565 - advanced pharmacology FINAL -
reveals hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment
for hyperthyroidism or Grave's disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine
5. Which of the following medications would be consid- C: Oral Metformin
ered the first line of treatment for a newly diagnosed
Diabetic patient with adequate renal and hepatic func-
tion?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
6. Of the following medications, which is most likely to B. Insulin
cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
7. Which symptoms are most expected of a patient diag- D. dry skin, brittle hair, fa-
nosed with hypothyroidism? tigue, myxedema
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
, NR 565 - advanced pharmacology FINAL -
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital C. Sodium-Glucose Co-
infections or an active diagnosis, should avoid what transporter 2 (SGLT-2) In-
drug class/es for treatment of Type II Diabetes? hibitors.
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) In-
hibitors.
D. All of the above.
9. A 45-year-old patient with a history of type 2 diabetes D. Metformin improves in-
presents to the clinic for a follow-up appointment. The sulin sensitivity and re-
healthcare provider has prescribed metformin as part duces hepatic glucose
of the treatment plan. Which of the following state- production.
ments regarding metformin is correct?
A. Metformin primarily stimulates insulin production
from the pancreas.
B. Metformin reduces glucose levels primarily by de-
creasing insulin resistance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces
hepatic glucose production.
10. In what part of the body are SGLT-2 (sodium-glucose C. Renal tubules
cotransporter 2) inhibitors active?
A. Small intestine
B. Pancreas
1. In which patient population is Metformin contraindi- C. Alcoholics
cated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
2. What lab value suggests metformin might be con- A. eGFR <30
traindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
3. What medication is contraindicated to treat diabetes if B. Thiazolidinediones
a patient already has a cardiac ejection fraction rate of
40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor
4. Sabrina is a 35-year-old female who presents with A. Methimazole
complaints of fatigue, anxiety, and palpitations. She
has a long history of obesity and reports that she is
happy that she has lost 23 pounds in the last 2 months.
She also reports that she has trouble sleeping and her
husband complains that she is keeping the house too
cold. Physical exam reveals slight tachycardia at 104
bpm and a slightly enlarged thyroid. Thyroid testing
, NR 565 - advanced pharmacology FINAL -
reveals hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment
for hyperthyroidism or Grave's disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine
5. Which of the following medications would be consid- C: Oral Metformin
ered the first line of treatment for a newly diagnosed
Diabetic patient with adequate renal and hepatic func-
tion?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
6. Of the following medications, which is most likely to B. Insulin
cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
7. Which symptoms are most expected of a patient diag- D. dry skin, brittle hair, fa-
nosed with hypothyroidism? tigue, myxedema
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
, NR 565 - advanced pharmacology FINAL -
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital C. Sodium-Glucose Co-
infections or an active diagnosis, should avoid what transporter 2 (SGLT-2) In-
drug class/es for treatment of Type II Diabetes? hibitors.
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) In-
hibitors.
D. All of the above.
9. A 45-year-old patient with a history of type 2 diabetes D. Metformin improves in-
presents to the clinic for a follow-up appointment. The sulin sensitivity and re-
healthcare provider has prescribed metformin as part duces hepatic glucose
of the treatment plan. Which of the following state- production.
ments regarding metformin is correct?
A. Metformin primarily stimulates insulin production
from the pancreas.
B. Metformin reduces glucose levels primarily by de-
creasing insulin resistance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces
hepatic glucose production.
10. In what part of the body are SGLT-2 (sodium-glucose C. Renal tubules
cotransporter 2) inhibitors active?
A. Small intestine
B. Pancreas
