NR 566 FINAL EXAM (2 LATEST VERSIONS 2025) / NR566 FINAL EXAM
100+ QUESTIONS & ANSWERS / ADVANCED PHARMACOLOGY FOR
CARE OF FAMILY|AGRADE
Phenytoin and contraceptive interaction - Answer: Makes OC's less effective, should have
backup or increase dose.
How is phenytoin effectiveness monitored? - Answer: Serum drug level.
Absence of seizures during trial drug period.
What anticonvulsant would be given for adjunctive therapy for partial seizures with or
without secondary generalization? - Answer: Lamotrigine
What medication (with example) can be used preventatively for migraines? - Answer: Beta
blockers such as metoprolol/propranolol
What is abortive therapy? - Answer: Abortive therapy is aimed at alleviating pain during
the aura phase (if present) or soon after the headache has started.
What are examples of abortive therapy for migraines? - Answer: NSAIDS, opioids,
triptans, ergot alkaloids
What is the first line treatment for acute mid/moderate migraines without vomiting? -
Answer: NSAIDs such as naproxen or ASA
When is it appropriate to prescribe a patient preventative therapy for migraines? -
Answer: Frequent attacks 3 or more a month, or attacks that do not respond to abortive
therapy, severe migraines.
What are examples of opioid analgesics for severe migraines? - Answer: Butorphanol nasal
spray. Spray each nostril Q60 min PRN
What is the mechanism of action for sumatriptan? - Answer: Suppresses release of CGRP
from trigeminal neurons.
This leads to vasoconstriction and decreased perivascular inflammation to relieve migraine
pain.
The first dose of triptan should be under medical supervision for what reason? - Answer:
In the case of any unknown underlying cardiac condition.
What are contraindications to triptans? - Answer: Ischemic heart disease
HTN
CV disease
Pregnancy
Basilar or hemiplegic migraine can cause cerebral vasoconstriction
Use of an ergot alkaline within 24 hours cause prolonged cerebral vasospasm
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What is rivastigmine (Exelon) used for? - Answer: Combat symptoms of Alzheimer's
disease. Slows progression of disease-not a cure
What are patient teachings for rivastigmine (Exelon)? - Answer: bradycardia, fainting, falls
risk, falls-related fractures.
What is Donepezil (Aricept) used to treat? - Answer: Symptoms of Alzheimer's disease
When would it be appropriate to increase the patient's dose of Donepezil (Aricept)? -
Answer: When the patient is stable on the initial dose for at least 1-3 months.
Cholinesterase inhibitor side effects are usually related to what? - Answer: Dosing. Dosing
should start low and titrate up.
Common dose-related side effects of cholinesterase inhibitors - Answer: Nausea, diarrhea,
insomnia.
What is the first line treatment for Chlamydia that only needs to be taken orally once? -
Answer: Azithromycin 1000mg
What is the first line treatment for Chlamydia that is taken BID for 7 days? - Answer:
Doxycycline 100mg
What is the IM treatment for uncomplicated gonorrhea? - Answer: Ceftriaxone 500mg
IM ceftriaxone can be given with or without this medication to treat gonorrhea. - Answer:
Doxycycline 100mg BID
Treatment for bacterial vaginosis in a non pregnant patient. - Answer: Metronidazole
500mg BID for 7 days
What are two treatments for bacterial vaginosis in a pregnant patient. - Answer: Vaginal
metronidazole 2% for 7 days.
Clindamycin 1% for 7 days.
First line treatment for HSV. - Answer: Acyclovir 400mg three times a day for 7-10 days.
Second line treatment for HSV. - Answer: Acyclovir 800mg BID for 5 days.
Trichomoniasis treatment for women. - Answer: Metronidazole 500mg BID for 7 days.
Tinidazole 2grams single dose.
Trichomoniasis treatment for men. - Answer: Metronidazole 2grams single dose.
Tinidazole 2grams single dose.