Molecular Diagnostics, 9th Edition by Nader Rifai, All 49
Chapters Covered
,Tietz yFundamentals yof yClinical yChemistry yand yMolecular yDiagnostics y9th y Edition yTest yBank
Table yof ycontents:
I. yPrinciples yOf yLaboratory yMedicine
Chapter y1. yClinical yChemistry, yMolecular yDiagnostics, yand yLaboratory yMedicine
Chapter y2. ySelection yand yAnalytical yEvaluation yof yMethods y— yWith yStatistical yTechniques
Chapter y3. yClinical yEvaluation yof yMethods
Chapter y4. yEvidence-Based yLaboratory yMedicine
Chapter y5. yEstablishment yand yUse yof yReference yValues
Chapter y6. ySpecimen yCollection, yProcessing, yand yOther yPreanalytical yVariables
Chapter y7. yQuality yManagement
II. yAnalytical yTechniques yAnd yInstrumentation
Chapter y8. yPrinciples yof yBasic yTechniques yand yLaboratory ySafety
Chapter y9. yOptical yTechniques
Chapter y10. yElectrochemistry yand yChemical ySensors
Chapter y11. yElectrophoresis
Chapter y12. yChromatography
Chapter y13. yMass ySpectrometry
Chapter y14. yEnzyme yand yRate yAnalyses
Chapter y15. yImmunochemical yTechniques
Chapter y16 yAutomation
Chapter y17. yPoint-of-Care yInstrumentation
III. y Analytes
Chapter y18. yAmino yAcids, yPeptides, yand yProteins
Chapter y19. ySerum yEnzymes
Chapter y20. yTumor yMarkers yand yCancer yGenes
Chapter y21. yKidney yFunction yTests y— yCreatinine, yGFR, yUrea, yand yUric yAcid
Chapter y22. yCarbohydrates
Chapter y23. yLipids, yLipoproteins, yApolipoproteins, yand yOther yCardiac yRisk yFactors
Chapter y24. yElectrolytes yand yBlood yGases
Chapter y25. yHormones
Chapter y26. y Catecholamines yand ySerotonin
Chapter y27. y Vitamins, yTrace yElements, yNutritional yAssessment
Chapter y28. yHemoglobin, yIron, yand yBilirubin
Chapter y29. yPorphyrins yand yPorphyrias
Chapter y30. yTherapeutic yDrugs yand yTheir yManagement
Chapter y31. yClinical yToxicology
Chapter y32. y Toxic yMetals
IV. y Pathophysiology
Chapter y33. yDiabetes
,Chapter y34. y Cardiovascular yDisease
Chapter y35. y Kidney yDisease
Chapter y36. y Physiology yand yDisorders yof yWater, yElectrolyte, yand yAcid-Base yMetabolism
Chapter y37. y Liver yDisease
Chapter y38. y Gastrointestinal yand yPancreatic yDiseases
Chapter y39. y Disorders yof yBone yand yMineral yMetabolism
Chapter y40. y Disorders yof ythe yPituitary yGland
Chapter y41. y Disorders yof ythe yAdrenal yCortex
Chapter y42. y Thyroid yDisorders
Chapter y43. y Reproduction-Related yDisorders
Chapter y44. y Pregnancy yand yPrenatal yTesting
Chapter y45. y Newborn yScreening yand yInborn yErrors yof yMetabolism
Chapter y46. yPharmacogenetics
V. y Molecular yDiagnostics
Chapter y47. yPrinciples yof yMolecular yBiology
Chapter y48. yNucleic yAcid yTechniques yand yApplications
Chapter y49. yGenomes yand yNucleic yAcid yAlterations
, Tietz yFundamentals yof yClinical yChemistry yand yMolecularDiagnostics, y9e yBurtis yTest yBank
Chapter y01: yClinical yChemistry, yMolecular yDiagnostics, yand yLaboratory yMedicineTest
yBank
MULTIPLE yCHOICE
1. An yindividual yworking yin ya yclinical ychemistry ylaboratory yis ymarried yto ya ysales
yrepresentative ywho yworks yfor ya ycompany ythat ysells ychemistry ylaboratory ysupplies. yWhen
ythe ylaboratory ymanager yrequests ya ylist yof yneeded ysupplies, ycost yof ysupplies, yand yvendors,
ythis yindividual yonly yrecommends ythe yspouse’s ycompany yas ythe yvendor. yThis yis
yconsidered yto ybe ya(n):
a. accounting yissue.
b. possible yconflict yof yinterest.
c. maintenance yof yconfidentiality yissue.
d. problem ywith yresource yallocation.
ANS: y B
Concern yhas ybeen yraised yover ythe yinterrelationships ybetween ypractitioners yin ythe ymedical
yfield yand ycommercial ysuppliers yof ydrugs, ydevices, yequipment, yetc., yto ythe ymedical
yprofession.
Similarly, yrelationships yhave ybeen yscrutinized ybetween yclinical ylaboratorians yand
ymanufacturers yand yproviders yof ydiagnostic yequipment yand ysupplies. yThese yconcerns yled
ythe yNational yInstitutes yof yHealth y(NIH) yin y1995 yto yrequire yofficial yinstitutional yreview yof
yfinancial ydisclosure yby yresearchers yand ymanagement yof ysituations yin ywhich ydisclosure
yindicates ypotential yconflicts yof yinterest.
DIF: 1 REF: y y Page y4-5 OBJ: y 6 y| y7
2. A ypatient yvisits yher yphysician ystating ythat yher yprescribed ypainkiller yis ynot yworking yto
yreduce ythe ypain yfollowing yher yrecent ysurgery. yA yfriend yof ythe ypatient yclaims ythat ythe
ysame ypainkiller y“worked ywonders” yto yreduce yher ypain yafter ythe ysame ysurgery. yThe
yphysician ystates ythat ythe ydifference yin ythe yeffect yof ythe ydrug ymight ybe ycaused yby ,
ywhich yis ystudied yin ypharmacogenetics.
a. epidemiology
b. an yinherited ydisease
c. a yconflict yof yinterest
d. a ygenetic yvariation yin ydrug-metabolizing yenzymes
ANS: y D
Pharmacogenetics yis ythe ystudy yof ythe ygenetic yvariation yof ydrug ymetabolism ybetween
yindividuals.
DIF: 1 REF: y y Page y3 OBJ: y 1
3. John yworks yin ya ymolecular ydiagnostics ylaboratory yand yreceives ya yblood ysample ythat yhas
ythe yname yof ya yclose yfriend yprinted yon ythe ybar-coded ylabel. yThe ygenetic ytest ythat yis
yordered yon ythe yfriend’s ysample ywould yprovide ydiagnostic yinformation yabout ya ydisorder
ythat yhas ya ypoor yprognosis, yand ythe ytest yis yusually yperformed yby yJohn. yHe yasks ya yfellow
yemployee yto yanalyze ythe ysample yfor yhim yand ynot ydivulge ythe yresults. yThis yethical yissue
yconcerns:
a. confidentiality yof ypatient ygenetic yand ymedical yinformation.
b. a yconflict yof yinterest.
c. resource yallocation.
d. diagnostic yaccuracy.