Week 7 Final Exam: NR546 / NR-546
(Latest ) Advanced
Pharmacology Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Study
Questions and Answers | 100%
Correct | Grade A - Chamberlain
Question:
Noradrenergic (NRI)
Answer:
atomoxetine (Strattera)
-drug of choice for adults with ADHD
-no abuse potential
-tolerated well when prescribed in twice daily dosing-appropriate choice for
comorbid substance abuse
-may augment the effects of antidepressants and antianxiety medications
-can be dosed at bedtime if fatigue is noted
-unlikely to worsen tics
,Question:
Atomoextine indication
Answer:
ADHD ages 6 and up
Question:
Atomoextine action
Answer:
-Blocks norepinephrine reuptake pumps, may also increase dopamine in PFC
Question:
Atomoextine dosage
Answer:
-For children 70 kg or less: initial dose 0.5 mg/kg per day
-For adults and children over 70 kg: initial dose 40 mg/day
Question:
Atomoextine side effects
Answer:
-Sedation, fatigue , decreased appetite, priapism (rare), hypotension
,Question:
Clonidine indications
Answer:
Hypertension
ADHD 6-17years of age
Question:
Clonidine dose
Answer:
0.1 mg at HS
Question:
Clonidine action
Answer:
• enhances precortical function for better mental focus
• appetite neutral
• may help with sleep disturbances, administer at bedtime
• adverse effects: sedation, brain fog, dry mouth
• monitor of BP closely during initial titration
• tapered to avoid rebound hypertension post discontinuation
, Question:
Guanfacine indication
Answer:
Hypertension, ADHD (6-17 years)
Question:
guanfacine dose
Answer:
1mg/day
Question:
Guanfacine action
Answer:
• may also be used for children with tics, sleep disturbances, or aggression
• tolerability and convenience enhanced by once-daily oral controlled-release
formulation
• adverse effects: sedation, headache, decreased appetite
• reduced side-effect profile comparable to clonidine
• bedtime administration to avoid daytime sedation
• central actions on postsynaptic alpha 2A receptors in the prefrontal cortex
(Latest ) Advanced
Pharmacology Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Study
Questions and Answers | 100%
Correct | Grade A - Chamberlain
Question:
Noradrenergic (NRI)
Answer:
atomoxetine (Strattera)
-drug of choice for adults with ADHD
-no abuse potential
-tolerated well when prescribed in twice daily dosing-appropriate choice for
comorbid substance abuse
-may augment the effects of antidepressants and antianxiety medications
-can be dosed at bedtime if fatigue is noted
-unlikely to worsen tics
,Question:
Atomoextine indication
Answer:
ADHD ages 6 and up
Question:
Atomoextine action
Answer:
-Blocks norepinephrine reuptake pumps, may also increase dopamine in PFC
Question:
Atomoextine dosage
Answer:
-For children 70 kg or less: initial dose 0.5 mg/kg per day
-For adults and children over 70 kg: initial dose 40 mg/day
Question:
Atomoextine side effects
Answer:
-Sedation, fatigue , decreased appetite, priapism (rare), hypotension
,Question:
Clonidine indications
Answer:
Hypertension
ADHD 6-17years of age
Question:
Clonidine dose
Answer:
0.1 mg at HS
Question:
Clonidine action
Answer:
• enhances precortical function for better mental focus
• appetite neutral
• may help with sleep disturbances, administer at bedtime
• adverse effects: sedation, brain fog, dry mouth
• monitor of BP closely during initial titration
• tapered to avoid rebound hypertension post discontinuation
, Question:
Guanfacine indication
Answer:
Hypertension, ADHD (6-17 years)
Question:
guanfacine dose
Answer:
1mg/day
Question:
Guanfacine action
Answer:
• may also be used for children with tics, sleep disturbances, or aggression
• tolerability and convenience enhanced by once-daily oral controlled-release
formulation
• adverse effects: sedation, headache, decreased appetite
• reduced side-effect profile comparable to clonidine
• bedtime administration to avoid daytime sedation
• central actions on postsynaptic alpha 2A receptors in the prefrontal cortex
