Test Bank for Integrated cardiopulmonary pharmacology 3rd edition by Bruce J Colbert Chapters 1-15 Covered

Test Bank For Pharmacology: An Introduction 7th Edition By He
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nry Hitner , Barbara Nagle 9781259718564 ALL Chapters .
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Identifyhthehmainhfunctionhofhmacrophagesh-
hANSWER:hMacrophagesharehscavengerhcellshthathengulfhand hdigesthinfectioushorganismshandhforeignhs

ubstances

IdentifyhthehrolehofhhelperhT-cellhlymphocyteshinhregulatinghthehactivityhofhthehimmunehsystemh-
hANSWER:hThehfunctionhofhhelperhT-

cellshishtohrecognizehthehforeignhantigenshpresentedhtohthemhbyhmacrophageshandhotherhantigen-
presentinghcells

Whichhofhthehfollowinghdiseaseshishanhimmune-
basedhdiseasehthathishtreatedhbyhsuppressinghthehimmunehresponse?h-hANSWER:hMultiplehsclerosis
Myastheniahgravis
Systemichlupusherythematosus

Whichhofhthehfollowinghishthehmainhimmunosuppressiveheffecthofhthehcorticosteroids?h-
hANSWER:hThehcorticosteroidshcausehlymphocyteshinhthehbloodhtohbehredistributedhintohthehbonehmarr

ow

Identifyhthehstatemenththathbesthexplainshhowhazathioprineh(Imuran)hworkshtohtreathlupusherythemato
sush-
hANSWER:hAzathioprineh{prevents}hthehproductionhofhadeninehandhguanine,hwhichhleadshtohthehsuppre

ssionhofhexistinghlymphocyteshandhsuppresseshthehformationhofhnewhB-cellshandhT-cells

Identifyhthehclinicalhindicationshforhthehusehofhmycophenolatehmofetilh(CellCept)h-
hANSWER:hMycophenolatehmofetilhishusedhinhrenalhorganhtransplantationhtohpreventhrejection.



Thehusehofhinfliximabh(Remicade)hleadshtohanhinfusionhreactionhthath-
hANSWER:hcanhincludehfever,hchills,hhives,hhypotension,handhchesthpain



Thehcommonhadverseheffectshofhthehusehofhinterferonshareh-hANSWER:hflu-
likehsymptomshsuchhashchills,hfever,handhmusclehacheshandhpains

Selecththehstatemenththathaccuratelyhdescribeshthehdifferencehbetweenhimmunomodulationhandhimm
unosuppressionh-hANSWER:hAllhofhtheseharehcorrect

Identifyhthehstatemenththathaccuratelyhexplainshthehsymptomshthathahpatienthbeinghadministeredhfilgr
astimh(Neupogen)hshouldhreporthtohthehphysicianh-
hANSWER:hThehpatienthshouldhimmediatelyhreporthtohthehphysicianhanyhfever,hchills,hGIhdisturbances,ha

ndhmusclehandhbonehpain

Identifyhthehtruehstatementhabouthmacrophagesh-hANSWER:hMacrophagesharehclassifiedhashantigen-
presentinghcells

Selecththehfalsehstatementhrelatedhtohthehadverseheffectshofhazathioprinehandhthehotherhcytotoxichdrug
sh-hANSWER:hNonehofhtheseharehfalse

Selecththehstatemenththathishcorrecthabouthtacrolimush(Prograf)handhcyclosporineh(Sandimmune)h-
hANSWER:hTacrolimushandhcyclosporinehinhibiththehT-cellhlymphocytehactivity



Selecththehtruehstatementhabouththehdifferencehbetweenhthehactionshofhinterleukin-
2h(Proleukin)handhthathofhcolonyhstimulatinghfactorsh(CSF)h-hANSWER:hInterleukin-2hstimulateshB-
cellhproductionhofhantibodieshandhkillerhT-

, cellhactivity,hwhereash{CSFshstimulatehthehbonehmarrow}htohincreasehthehproductionhofhmacrophagesha
ndhgranulocytes

Selecththehtruehstatementhabouththehmechanismhofhactionhofhahnaturalhkillerhcellh-
hANSWER:hThehnaturalhkillerhcellhreleaseshperforinshthathformhahholehinhthehenemyhcellhmembrane

Granzymeshfromhthehnaturalhkillerhcellhenterhthehperforinhholehandhdegradehthehenemyhcellhenzymes
Thehenemyhcellhdieshbyhapoptosis,handhthehmacrophagehengulfshandhdigestshthehdyinghcell

Selecththehfalsehstatementhabouththeheffecthofhlymphopeniahonhthehimmunehresponsehfollowinghadmi
nistrationhofhimmunosuppressivehdrugshlikehthehcorticosteroidsh-
hANSWER:hCorticosteroidshincreasehthehamounthofhlymphoidhtissuehandhcellshinhthehlymphhnodeshandh

spleen

Selecththehfalsehstatementhabouthmemoryhcellshandhtheirhrolehinhthehimmunehresponsehprocesshinhtheh
bodyh-
hANSWER:hMemoryhcellsharehlymphocyteshthathinhibiththehactivityhofhthehimmunehsystemhwhenhthehim

munehresponsehishnohlongerhneeded

Memoryhcellshremainhinhthehbodyhforhmanyhyearshandhcanhquicklyhbecomehreactivatedhtohproducehanhi
mmunehresponsehagainsthanhorganismhthathpreviouslyhinfectedhthehbodyh-
hANSWER:hNonehofhtheseharehfalse



Selecththehtruehstatementhrelatedhtohthehalkylatinghdrughcyclosporineh(Sandimmune)h-
hANSWER:hCyclosporinehinhibitshthehproductionhofhinterleukin-2



Selecththehtruehstatementhabouthinfliximabh(Remicade)h-
hANSWER:hInfliximabhishahmonoclonalhantibodyhthathbindshtohandhinhibitshthehactivityhofhtumorhnecrosi

shfactorh(TNF-alpha)

Samuel,hwhohhashbeenhdiagnosedhwithhlupusherythematosus,hishprescribedhahcytotoxichdrug.hHishdocto
rhexplainshthaththehdrughishconvertedhinhthehbodyhtohmercaptopurine,hwhichhexertshahcytotoxicheffect.h
IthinhibitshthehsynthesishofhpurinehnucleotideshthatharehrequiredhforhDNAhsynthesis.hWhichhofhthehfollo
winghdrugshhashSamuelhbeenhprescribed?h-hANSWER:hAzathioprine

Ethanhishscheduledhforhanhorganhtransplant.hHehishadministeredhahdrughtohpreventhorganhrejection.hTh
ehdrughworkshbyhsuppressinghT-
cellhfunction.hWhichhofhthehfollowinghdrugshhashEthanhbeenhadministered?h-hANSWER:hSandimmune

Loganhishdiagnosedhwithhrheumatoidharthritis.hHehishprescribedhahdrughthathishtohbehtakenhorally.hLoga
nhishinformedhbyhhishdoctorhthaththehdrughhashahhalf-
lifehofh15hdays.hHehalsohexplainshthathhehmayhexperiencehdiarrhea.hWhichhofhthehfollowinghdrugshhashL
oganhbeenhprescribed?h-hANSWER:hArava

Gabrielhishdiagnosedhwithhhairyhcellhleukemia.hHehishprescribedhanhimmunomodulatinghagenththathisha
dministeredhthroughhintramuscularhinjections.hWhichhofhthehfollowinghdrugshhashGabrielhbeenhprescri
bed?h-hANSWER:hIntronhA

Fatimahishsufferinghfromhmultiplehsclerosis.hShehishbeinghadministeredhahdrughthroughhsubcutaneoushin
jectionshthreehtimeshahweek.hWhichhofhthehfollowinghdrugshishFatimahbeinghadministered?h-
hANSWER:hAvonex



_____hishanhimmunomodulatinghagenththathishadministeredhthroughhslowhIVhinfusionhtohtreathrenalhcel
lhcancerh-hANSWER:hProleukin

_____hishanhimmunomodulatinghagenththathishusedhtohtreathKaposi'shsarcomah-hANSWER:hRoferon-A