FULL TEST BANK FOR_
Lehne's Pharmacology for Nursing Care 11th Edition by Jacqueline Rosenjack Burchum DNSc
FNP-BC CNE Laura D. Rosenthal DNP RN ACNP-BC FAANP (2021) ||ALL CHAPTERS (01 – 112) ||
VERIFIED ANSWERS|| 978-0323825221 COMPLETE GUIDE
11TH EDITION
,Table of Contents
UNIT I: INTRODUCTION ................................................................................................................................. 7
Chapter 01: Orientation To Pharmacology ............................................................................................... 7
Chapter 02: Application Of Pharmacology In Nursing Practice ................................................................ 9
Chapter 03: Drug Regulation, Development, Names, And Information ................................................. 16
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ........................................................................................ 19
Chapter 04: Pharmacokinetics ................................................................................................................ 19
Chapter 05: Pharmacodynamics ............................................................................................................. 26
Chapter 06: Drug Interactions ................................................................................................................ 30
Chapter 07: Adverse Drug Reactions And Medication Errors ................................................................. 36
Chapter 08: Individual Variation To Drug Responses ............................................................................. 43
Chapter 09: Genetic And Genomic Considerations ................................................................................ 48
Chapter 10: Introduction To Immunomodulators .................................................................................. 52
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ....................................................................................... 56
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding......................................................... 56
Chapter 12: Drug Therapy In Pediatric Patients ..................................................................................... 61
Chapter 13: Drug Therapy In Older Adults.............................................................................................. 66
UNIT IV: CENTRAL NERVOUS SYSTEM DRUGS ............................................................................................ 73
Chapter 14: Basic Principles Of Neuropharmacology ............................................................................. 73
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................... 77
Chapter 16: Muscarinic Agonists ............................................................................................................ 81
Chapter 17: Muscarinic Antagonists ....................................................................................................... 85
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis .......................................... 90
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ......................................................... 94
Chapter 20: Adrenergic Agonists ............................................................................................................ 99
Chapter 21: Adrenergic Antagonists ..................................................................................................... 105
Chapter 22: Indirect-Acting Antiadrenergic Agents .............................................................................. 112
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................... 118
Chapter 23: Introduction To Central Nervous System Pharmacology .................................................. 118
Chapter 24: Drugs For Parkinson Disease ............................................................................................. 122
Chapter 25: Drugs For Alzheimer Disease............................................................................................. 129
Chapter 26: Drugs For Multiple Sclerosis.............................................................................................. 134
Chapter 27: Drugs For Seizure Disorders .............................................................................................. 140
, Chapter 28: Drugs For Muscle Spasm And Spasticity ........................................................................... 149
Chapter 29: Local Anesthetics............................................................................................................... 154
Chapter 30: General Anesthetics .......................................................................................................... 159
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics ....... 166
Chapter 32: Pain Management In Patients With Cancer ...................................................................... 173
Chapter 33: Drugs For Headache .......................................................................................................... 182
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ..................................................... 188
Chapter 35: Antidepressants ................................................................................................................ 195
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 204
Chapter 37: Sedative-Hypnotic Drugs ................................................................................................... 210
Chapter 38: Management Of Anxiety Disorders ................................................................................... 218
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ........ 223
Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................. 228
Chapter 41: Substance Use Disorders II: Alcohol.................................................................................. 233
Chapter 42: Substance Use Disorders III: Nicotine ............................................................................... 241
Chapter 43: Substance Use Disorders IV: Major Drugs Of Abuse Other Than Alcohol And Nicotine... 246
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ......................................................... 254
Chapter 44: Diuretics ............................................................................................................................ 254
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ........................................ 259
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ............................................. 265
Chapter 46: Review Of Hemodynamics ................................................................................................ 265
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ......................................... 269
Chapter 48: Calcium Channel Blockers ................................................................................................. 275
Chapter 49: Vasodilators....................................................................................................................... 278
Chapter 50: Drugs For Hypertension .................................................................................................... 283
Chapter 51: Drugs For Heart Failure ..................................................................................................... 292
Chapter 52: Antidysrhythmic Drugs ...................................................................................................... 301
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ...................................... 311
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 319
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ...................................................... 327
Chapter 56: Management Of ST-Elevation Myocardial Infarction ....................................................... 336
Chapter 57: Drugs For Hemophilia ....................................................................................................... 341
Chapter 58: Drugs For Deficiency Anemias........................................................................................... 347
, Chapter 59: Hematopoietic Agents....................................................................................................... 354
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ....................................................................................... 359
Chapter 60: Drugs For Diabetes Mellitus .............................................................................................. 359
Chapter 61: Drugs For Thyroid Disorders ............................................................................................. 367
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function................................................... 374
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ...................................................................... 380
UNIT IX: WOMEN'S HEALTH ...................................................................................................................... 385
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications ..... 385
Chapter 65: Birth Control ...................................................................................................................... 390
Chapter 66: Drug Therapy For Infertility ............................................................................................... 397
Chapter 67: Drugs That Affect Uterine Function .................................................................................. 403
UNIT X: MEN'S HEALTH ............................................................................................................................. 409
Chapter 68: Androgens ......................................................................................................................... 409
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ................................... 414
UNIT XI: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ....................................... 420
Chapter 70: Review Of The Immune System ........................................................................................ 420
Chapter 71: Childhood Immunization ................................................................................................... 425
Chapter 72: Immunosuppressants ........................................................................................................ 432
Chapter 73: Antihistamines .................................................................................................................. 438
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
.............................................................................................................................................................. 444
Chapter 75: Glucocorticoids In Nonendocrine Disorders ..................................................................... 451
UNIT XII: DRUGS FOR BONE AND JOINT DISORDERS ................................................................................ 458
Chapter 76: Drug Therapy For Rheumatoid Arthritis............................................................................ 458
Chapter 77: Drug Therapy For Gout...................................................................................................... 462
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ................................................ 466
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease...................................... 475
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds ................................................................... 484
UNIT XIV: GASTROINTESTINAL DRUGS...................................................................................................... 491
Chapter 81: Drugs For Peptic Ulcer Disease ......................................................................................... 491
Chapter 82: Laxatives ............................................................................................................................ 497
UNIT XV: NUTRITION AND COMPLIMENTARY THERAPY ........................................................................... 504
Chapter 83: Other Gastrointestinal Drugs ............................................................................................ 504
, Chapter 84: Vitamins ............................................................................................................................ 514
Chapter 85: Drugs For Weight Loss....................................................................................................... 521
Chapter 86: Complementary And Alternative Therapy ........................................................................ 528
UNIT XVI: THERAPY OF INFECTIOUS DISEASES.......................................................................................... 532
Chapter 87: Basic Principles Of Antimicrobial Therapy ........................................................................ 532
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins .................................................. 538
Chapter 89: Drugs That Weaken The Bacterial Cell Wall II: Other Drugs ............................................. 546
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others ... 552
Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis......................................... 561
Chapter 92: Sulfonamides And Trimethoprim ...................................................................................... 569
Chapter 93: Drug Therapy For Urinary Tract Infections ....................................................................... 575
Chapter 94: Antimycobacterial Agents ................................................................................................. 582
Chapter 95: Miscellaneous Antibacterial Drugs.................................................................................... 592
Chapter 96: Antifungal Agents .............................................................................................................. 597
Chapter 97: Antiviral Agents I: Drugs For Non-HIV Viral Infections ...................................................... 607
Chapter 98: Antiviral Agents II: Drugs For HIV Infection And Related Opportunistic Infections .......... 614
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ............................................................. 620
Chapter 100: Antiseptics And Disinfectants ......................................................................................... 625
UNIT XVII: CHEMOTHERAPY OF PARASITIC DISEASES............................................................................... 630
Chapter 101: Anthelmintics .................................................................................................................. 630
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents .................................................................... 635
Chapter 103: Antiprotozoal Drugs II: Miscellaneous Agents ................................................................ 640
Chapter 104: Ectoparasiticides ............................................................................................................. 643
UNIT XVIII: CANCER CHEMOTHERAPY....................................................................................................... 648
Chapter 105: Basic Principles Of Cancer Chemotherapy ...................................................................... 648
Chapter 106: Anticancer Drugs I: Cytotoxic Agents .............................................................................. 656
Chapter 107: Anticancer Drugs II: Noncytotoxic Agents....................................................................... 664
UNIT XIX: MISCELLANEOUS DRUGS AND THERAPIES................................................................................ 669
Chapter 108: Drugs For The Eye ........................................................................................................... 669
Chapter 109: Drugs For The Skin .......................................................................................................... 676
Chapter 110: Drugs For The Ear ............................................................................................................ 685
UNIT XX: TOXICOLOGY .............................................................................................................................. 691
Chapter 111: Management Of Poisoning ............................................................................................. 691
,Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ............................ 696
,UNIT I: INTRODUCTION
Chapter 01: Orientation To Pharmacology
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
MULTIPLE CHOICE
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This, The
Nurse Will Rely On Knowledge Of Which Topic?
A. Clinical Pharmacology
B. Drug Efficacy
C. Pharmacokinetics
D. Pharmacotherapeutics
CORRECT ANS>>D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent Conditions.
Clinical Pharmacology Is Concerned With All Aspects Of Drug-Human Interactions. Drug Efficacy
Measures The Extent To Which A Given Drug Causes An Intended Effect. Pharmacokinetics Is The Study
Of The Impact Of The Body On A Drug.
PTS: 1
2. What Is A Desired Outcome When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
CORRECT ANS>>C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More Likely To
Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other Attributes Listed, But
Those Properties Are Independent Of Ease Of Administration.
PTS: 1
, 3. A Patient Tells The Nurse That An Analgesic He Will Begin Taking May Cause Drowsiness And
Will Decrease Pain Up To 4 Hours At A Time. Based On This Understanding Of The Drug’s Effects By The
Patient, The Nurse Will Anticipate Which Outcome?
A. Decreased Chance Of Having A Placebo Effect
B. Decreased Motivation To Take The Drug
C. Improved Compliance With The Drug Regimen
D. Increased Likelihood Of Drug Overdose
CORRECT ANS>>C
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects. Patients Who
Understand Both The Risks And Benefits Of Taking A Medication Are More Likely To Comply With The
Drug Regimen.
PTS: 1
MULTIPLE RESPONSE
1. What Are Considered The ‘Big Three’ Properties Of An Ideal Drug? (Select All That Apply.)
A. Irreversible Action
B. Effectiveness
C. Safety
D. Selectivity
E. A Recognizable Trade Name
CORRECT ANS>>B, C, D
The ‘Big Three’ Properties Of The Ideal Drug Are Effectiveness, Safety, And Selectivity. PTS: 1
2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate How
Individual Patient Variability Might Affect The Patient’s Response To The Medication? (Select All That
Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
Lehne's Pharmacology for Nursing Care 11th Edition by Jacqueline Rosenjack Burchum DNSc
FNP-BC CNE Laura D. Rosenthal DNP RN ACNP-BC FAANP (2021) ||ALL CHAPTERS (01 – 112) ||
VERIFIED ANSWERS|| 978-0323825221 COMPLETE GUIDE
11TH EDITION
,Table of Contents
UNIT I: INTRODUCTION ................................................................................................................................. 7
Chapter 01: Orientation To Pharmacology ............................................................................................... 7
Chapter 02: Application Of Pharmacology In Nursing Practice ................................................................ 9
Chapter 03: Drug Regulation, Development, Names, And Information ................................................. 16
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ........................................................................................ 19
Chapter 04: Pharmacokinetics ................................................................................................................ 19
Chapter 05: Pharmacodynamics ............................................................................................................. 26
Chapter 06: Drug Interactions ................................................................................................................ 30
Chapter 07: Adverse Drug Reactions And Medication Errors ................................................................. 36
Chapter 08: Individual Variation To Drug Responses ............................................................................. 43
Chapter 09: Genetic And Genomic Considerations ................................................................................ 48
Chapter 10: Introduction To Immunomodulators .................................................................................. 52
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ....................................................................................... 56
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding......................................................... 56
Chapter 12: Drug Therapy In Pediatric Patients ..................................................................................... 61
Chapter 13: Drug Therapy In Older Adults.............................................................................................. 66
UNIT IV: CENTRAL NERVOUS SYSTEM DRUGS ............................................................................................ 73
Chapter 14: Basic Principles Of Neuropharmacology ............................................................................. 73
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................... 77
Chapter 16: Muscarinic Agonists ............................................................................................................ 81
Chapter 17: Muscarinic Antagonists ....................................................................................................... 85
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis .......................................... 90
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ......................................................... 94
Chapter 20: Adrenergic Agonists ............................................................................................................ 99
Chapter 21: Adrenergic Antagonists ..................................................................................................... 105
Chapter 22: Indirect-Acting Antiadrenergic Agents .............................................................................. 112
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................... 118
Chapter 23: Introduction To Central Nervous System Pharmacology .................................................. 118
Chapter 24: Drugs For Parkinson Disease ............................................................................................. 122
Chapter 25: Drugs For Alzheimer Disease............................................................................................. 129
Chapter 26: Drugs For Multiple Sclerosis.............................................................................................. 134
Chapter 27: Drugs For Seizure Disorders .............................................................................................. 140
, Chapter 28: Drugs For Muscle Spasm And Spasticity ........................................................................... 149
Chapter 29: Local Anesthetics............................................................................................................... 154
Chapter 30: General Anesthetics .......................................................................................................... 159
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics ....... 166
Chapter 32: Pain Management In Patients With Cancer ...................................................................... 173
Chapter 33: Drugs For Headache .......................................................................................................... 182
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ..................................................... 188
Chapter 35: Antidepressants ................................................................................................................ 195
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 204
Chapter 37: Sedative-Hypnotic Drugs ................................................................................................... 210
Chapter 38: Management Of Anxiety Disorders ................................................................................... 218
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ........ 223
Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................. 228
Chapter 41: Substance Use Disorders II: Alcohol.................................................................................. 233
Chapter 42: Substance Use Disorders III: Nicotine ............................................................................... 241
Chapter 43: Substance Use Disorders IV: Major Drugs Of Abuse Other Than Alcohol And Nicotine... 246
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ......................................................... 254
Chapter 44: Diuretics ............................................................................................................................ 254
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ........................................ 259
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ............................................. 265
Chapter 46: Review Of Hemodynamics ................................................................................................ 265
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ......................................... 269
Chapter 48: Calcium Channel Blockers ................................................................................................. 275
Chapter 49: Vasodilators....................................................................................................................... 278
Chapter 50: Drugs For Hypertension .................................................................................................... 283
Chapter 51: Drugs For Heart Failure ..................................................................................................... 292
Chapter 52: Antidysrhythmic Drugs ...................................................................................................... 301
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ...................................... 311
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 319
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ...................................................... 327
Chapter 56: Management Of ST-Elevation Myocardial Infarction ....................................................... 336
Chapter 57: Drugs For Hemophilia ....................................................................................................... 341
Chapter 58: Drugs For Deficiency Anemias........................................................................................... 347
, Chapter 59: Hematopoietic Agents....................................................................................................... 354
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ....................................................................................... 359
Chapter 60: Drugs For Diabetes Mellitus .............................................................................................. 359
Chapter 61: Drugs For Thyroid Disorders ............................................................................................. 367
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function................................................... 374
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ...................................................................... 380
UNIT IX: WOMEN'S HEALTH ...................................................................................................................... 385
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications ..... 385
Chapter 65: Birth Control ...................................................................................................................... 390
Chapter 66: Drug Therapy For Infertility ............................................................................................... 397
Chapter 67: Drugs That Affect Uterine Function .................................................................................. 403
UNIT X: MEN'S HEALTH ............................................................................................................................. 409
Chapter 68: Androgens ......................................................................................................................... 409
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ................................... 414
UNIT XI: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ....................................... 420
Chapter 70: Review Of The Immune System ........................................................................................ 420
Chapter 71: Childhood Immunization ................................................................................................... 425
Chapter 72: Immunosuppressants ........................................................................................................ 432
Chapter 73: Antihistamines .................................................................................................................. 438
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
.............................................................................................................................................................. 444
Chapter 75: Glucocorticoids In Nonendocrine Disorders ..................................................................... 451
UNIT XII: DRUGS FOR BONE AND JOINT DISORDERS ................................................................................ 458
Chapter 76: Drug Therapy For Rheumatoid Arthritis............................................................................ 458
Chapter 77: Drug Therapy For Gout...................................................................................................... 462
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ................................................ 466
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease...................................... 475
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds ................................................................... 484
UNIT XIV: GASTROINTESTINAL DRUGS...................................................................................................... 491
Chapter 81: Drugs For Peptic Ulcer Disease ......................................................................................... 491
Chapter 82: Laxatives ............................................................................................................................ 497
UNIT XV: NUTRITION AND COMPLIMENTARY THERAPY ........................................................................... 504
Chapter 83: Other Gastrointestinal Drugs ............................................................................................ 504
, Chapter 84: Vitamins ............................................................................................................................ 514
Chapter 85: Drugs For Weight Loss....................................................................................................... 521
Chapter 86: Complementary And Alternative Therapy ........................................................................ 528
UNIT XVI: THERAPY OF INFECTIOUS DISEASES.......................................................................................... 532
Chapter 87: Basic Principles Of Antimicrobial Therapy ........................................................................ 532
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins .................................................. 538
Chapter 89: Drugs That Weaken The Bacterial Cell Wall II: Other Drugs ............................................. 546
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others ... 552
Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis......................................... 561
Chapter 92: Sulfonamides And Trimethoprim ...................................................................................... 569
Chapter 93: Drug Therapy For Urinary Tract Infections ....................................................................... 575
Chapter 94: Antimycobacterial Agents ................................................................................................. 582
Chapter 95: Miscellaneous Antibacterial Drugs.................................................................................... 592
Chapter 96: Antifungal Agents .............................................................................................................. 597
Chapter 97: Antiviral Agents I: Drugs For Non-HIV Viral Infections ...................................................... 607
Chapter 98: Antiviral Agents II: Drugs For HIV Infection And Related Opportunistic Infections .......... 614
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ............................................................. 620
Chapter 100: Antiseptics And Disinfectants ......................................................................................... 625
UNIT XVII: CHEMOTHERAPY OF PARASITIC DISEASES............................................................................... 630
Chapter 101: Anthelmintics .................................................................................................................. 630
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents .................................................................... 635
Chapter 103: Antiprotozoal Drugs II: Miscellaneous Agents ................................................................ 640
Chapter 104: Ectoparasiticides ............................................................................................................. 643
UNIT XVIII: CANCER CHEMOTHERAPY....................................................................................................... 648
Chapter 105: Basic Principles Of Cancer Chemotherapy ...................................................................... 648
Chapter 106: Anticancer Drugs I: Cytotoxic Agents .............................................................................. 656
Chapter 107: Anticancer Drugs II: Noncytotoxic Agents....................................................................... 664
UNIT XIX: MISCELLANEOUS DRUGS AND THERAPIES................................................................................ 669
Chapter 108: Drugs For The Eye ........................................................................................................... 669
Chapter 109: Drugs For The Skin .......................................................................................................... 676
Chapter 110: Drugs For The Ear ............................................................................................................ 685
UNIT XX: TOXICOLOGY .............................................................................................................................. 691
Chapter 111: Management Of Poisoning ............................................................................................. 691
,Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ............................ 696
,UNIT I: INTRODUCTION
Chapter 01: Orientation To Pharmacology
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
MULTIPLE CHOICE
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This, The
Nurse Will Rely On Knowledge Of Which Topic?
A. Clinical Pharmacology
B. Drug Efficacy
C. Pharmacokinetics
D. Pharmacotherapeutics
CORRECT ANS>>D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent Conditions.
Clinical Pharmacology Is Concerned With All Aspects Of Drug-Human Interactions. Drug Efficacy
Measures The Extent To Which A Given Drug Causes An Intended Effect. Pharmacokinetics Is The Study
Of The Impact Of The Body On A Drug.
PTS: 1
2. What Is A Desired Outcome When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
CORRECT ANS>>C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More Likely To
Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other Attributes Listed, But
Those Properties Are Independent Of Ease Of Administration.
PTS: 1
, 3. A Patient Tells The Nurse That An Analgesic He Will Begin Taking May Cause Drowsiness And
Will Decrease Pain Up To 4 Hours At A Time. Based On This Understanding Of The Drug’s Effects By The
Patient, The Nurse Will Anticipate Which Outcome?
A. Decreased Chance Of Having A Placebo Effect
B. Decreased Motivation To Take The Drug
C. Improved Compliance With The Drug Regimen
D. Increased Likelihood Of Drug Overdose
CORRECT ANS>>C
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects. Patients Who
Understand Both The Risks And Benefits Of Taking A Medication Are More Likely To Comply With The
Drug Regimen.
PTS: 1
MULTIPLE RESPONSE
1. What Are Considered The ‘Big Three’ Properties Of An Ideal Drug? (Select All That Apply.)
A. Irreversible Action
B. Effectiveness
C. Safety
D. Selectivity
E. A Recognizable Trade Name
CORRECT ANS>>B, C, D
The ‘Big Three’ Properties Of The Ideal Drug Are Effectiveness, Safety, And Selectivity. PTS: 1
2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate How
Individual Patient Variability Might Affect The Patient’s Response To The Medication? (Select All That
Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
