6TH EDITION BY JOHN WILSON (AUTHOR), TIM HUNT (AUTHOR)− COMPLETE
GUIDE| ALL CHAPTERS INCLUDED(1 -20) 1OO% VERIFIED QUESTIONS &
DETAILED SOLUTIONS| LATEST UPDATE| RATED A+
,Table of Contents
Chapter 1: Cells And Genomes..................................................................................................................... 2
Chapter 2: Cell Chemistry And Bioenergetics ............................................................................................ 18
Chapter 3: Proteins..................................................................................................................................... 50
Chapter 4: Dna, Chromosomes, And Genomes ......................................................................................... 80
Chapter 5: Dna Replication, Repair, And Recombination ....................................................................... 115
Chapter 6: How Cells Read The Genome: From Dna To Protein ............................................................. 142
Chapter 7: Control Of Gene Expression ................................................................................................... 174
Chapter 8: Analyzing Cells, Molecules,And Systems ............................................................................... 193
Chapter 9: Visualizing Cells ...................................................................................................................... 216
Chapter 10: Membrane Structure............................................................................................................ 233
Chapter 11: Membrane Transport Of Small Molecules And The Electrical Properties Of Membranes 248
Chapter 12: Intracellular Compartments And Protein Sorting ............................................................... 275
Chapter 13: Intracellular Membrane Traffic............................................................................................ 292
Chapter 14: Energy Conversion: Mitochondria And Chloroplasts .......................................................... 321
Chapter 15: Cell Signaling......................................................................................................................... 347
Chapter 16: The Cytoskeleton .................................................................................................................. 389
Chapter 17: The Cell Cycle ........................................................................................................................ 430
Chapter 18: Cell Death ............................................................................................................................. 465
Chapter 19: Cell Junctions And The Extracellular Matrix ........................................................................ 470
Chapter 20: Cancer ................................................................................................................................... 503
Molecular Biology Of The Cell, Sixth Edition
Chapter 1: Cells And Genomes
1. Scientists Discover More Than Ten Thousand New Species Of Living Organisms Every Year. What
Is Shared Between All Of These Organisms?
A. They Are Made Of Cells, Whose Nuclei Enclose Their Dna.
B. They Obtain Their Energy From Sunlight.
C. They Produce And Use Adenosine Triphosphate (Atp).
D. Their Genome Contains At Least 1000 Genes.
E. All Of The Above.
, CORRECT ANS>>C
Difficulty: 2
Section: The Universal Features Of Cells On Earth
Feedback: All Living Organisms Are Made Of Cells. However, Only A Minority Of Them Are
Eukaryotes With Defined Cell Nuclei. Not All Cells Obtain Their Energy Directly From Sunlight.
However, Regardless Of The Energy Source, The Main Energy Currency Used By All Known Living
Cells Is Atp. Some Prokaryotic Genomes Contain Only A Few Hundred Genes.
2. All Cells ...
A. Have Membrane Transport Proteins.
B. Synthesize Proteins On The Ribosome.
C. Replicate Their Genome By Dna Polymerization.
D. Transcribe Their Genetic Information By Rna Polymerization.
E. All Of The Above.
CORRECT ANS>>E
Difficulty: 1
Section: The Universal Features Of Cells On Earth
Feedback: All Living Cells Replicate Their Dna By The Same Overall Mechanism Of Templated
Polymerization. They Also Transcribe The Genetic Information Into Rna Form Using The Same
Mechanism. Translation Of This Information Into Protein Form Is Mediated By The Ribosome In
All Cells. Additionally, All Cellular Membranes Have Membrane Transport Proteins That Control
The Flow Of Material Through The Membranes.
3. Imagine A Segment Of Dna (Within A Gene) Encoding A Certain Amount Of Information In Its
Nucleotide Sequence. When This Segment Is Fully Transcribed Into Mrna And Then Translated
Into Protein, In General, ...
A. The Protein Sequence Would Carry More Information Compared To The Dna And Mrna
Sequences, Because Its Alphabet Has 20 Letters.
B. The Protein Sequence Would Carry Less Information Compared To The Dna And Mrna
Sequences, Because Several Codons Can Correspond To One Amino Acid.
C. The Amount Of Information In The Mrna Sequence Is Lower, Because The Mrna Has
Been Transcribed Using Only One Of The Dna Strands As The Template.
, D. The Amount Of Information In The Mrna Sequence Is Higher, Because Several Mrna
Molecules Can Be Transcribed From One Dna Molecule.
CORRECT ANS>>B
Difficulty: 3
Section: The Universal Features Of Cells On Earth
Feedback: There Are 64 (That Is, 4^3) Nucleotide Triplets Or Codons Using Four Types Of
Nucleotide Monomers, Whereas Each Codon Encodes One Out Of Only 20 Amino Acids.
Therefore, Some Sequence Information Is Lost When Translating From Mrna To Protein
Sequences, Such That It Is Not Usually Possible To Deduce The Original Mrna Sequence Given A
Translated Polypeptide Sequence.
4. Which Of The Following Processes That Happens Inside A Cell Does Not Normally Require
Consumption Of Free Energy By The Cell?
A. Replication Of The Genetic Material
B. Import Of Nutrients From The Environment
C. Diffusion Of Small Molecules Within The Cell
D. Regulation Of Gene Expression
E. Synthesis Of Enzymes That Catalyze Cellular Reactions
CORRECT ANS>>C
Difficulty: 2
Section: The Universal Features Of Cells On Earth
Feedback: Diffusion Is A Spontaneous Process Driven By The Thermal Energy Of Randomly
Moving Molecules, And Normally Does Not Require Energy Expenditure By The Cell. For The
Other Mentioned Processes, Free Energy Is Required. If A Cell "Dies," These Processes Would
Stop Or Get Out Of Control, But Small Molecules Would Still Diffuse.
5. Which Of The Following Would You Not Expect To Find In A Bacterial Cell?
A. Swimming Using Flagella
B. Having A Cell Wall Around The Plasma Membrane
C. Atp Production In Mitochondria
D. Protein Production On The Ribosome
E. Sexual Exchange Of Dna With Other Bacteria
CORRECT ANS>>C
Difficulty: 2
Section: The Diversity Of Genomes And The Tree Of Life