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Midterm Exam: NR 566/ NR566 (Latest 2025/ 2026 Update) Advanced Pharmacology for Care of the Family Guide| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Chamberlain

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Midterm Exam: NR 566/ NR566 (Latest 2025/ 2026 Update) Advanced Pharmacology for Care of the Family Guide| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Chamberlain Q: How do you treat C. Diff? Answer: Metronidazole (vancomycin is alternative) D/c abx (any abx can cause C. Diff) No antidiarrheal Q: Drugs that promote development of C. Diff Answer: cephalosporins, clindamycin Q: Cross sensitivity for penicillin Answer: cephalosporins Q: Penicillin and pregnancy Answer: Ok to take while pregnant Q: Cephalosporin patient education Answer: patients should report increase in stool frequency d/t risk for c diff Q: Cephalosporin and pregnancy Answer: Cephalosporins are ok Q: Tetracycline patient education Answer: Tetra=4 (avoid Milk, Calcium, Iron, Magnesium) Avoid exposure to sun or tanning beds Many drug interactions including digoxin Q: Tertracycline and pregnancy Answer: Avoid in pregnancy and with lactation Q: Do not take macrolides if (2 options) Answer: 1 - Do not take with prolonged QT. When macrolides are combined with CYP3A4 inhibitors (like CCB and antifungals), there is a fivefold increase in sudden cardiac death. 2 - Macrolides inhibit P450 enzymes, which normally help metabolize drugs. Without their action, there is a risk for drug toxicity with theophylline, carbamazepine, and warfarin. Q: Which antibiotic inhibits CYP450 enzymes and increases levels of theophylline, warfarin, and carbamazepine? Answer: Macrolides Q: Aminoglycoside patient education Answer: patients should report symptoms of ototoxicity Q: Sulfonamide patient education Answer: drink 8-10 glasses of water per day to prevent crystalluria avoid sun and tanning watch for hypersensitivity syndrome (drug reaction when body responds to a drug the way it would respond to an infection - T cells respond and there can be damage to organs) Q: Sulfonamides and pregnancy Answer: birth defects if taken in T1 kernicterus risk if given at term AND if given during lactation to infant <2mo (potentially fatal, caused by bilirubin deposits in the brain - bilirubin is neurotoxic and can cause severe neurological deficits and death) Q: Renal adjustments with gentamicin Answer: decrease dose or increase interval between doses if concern for renal impairment Q: antimicrobial sensitivity testing Answer: lab test to determine how pathogens grow when exposed to certain drugs in a Petri dish (susceptible, resistant or intermediate) Q: Considerations fro antibiotic treatment Answer: Host (patient) Syndrome (illness) Pathogen (cultures help identify) Drugs

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Uploaded on
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  • how do you treat c di

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Midterml Exam:l NRl 566/l NR566l (Latestl
2025/l 2026l Update)l Advancedl
Pharmacologyl forl Carel ofl thel Familyl
Guide|l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solutions)-l
Chamberlain

Q:l Howl dol youl treatl C.l Diff?

Answer:
Metronidazolel (vancomycinl isl alternative)
D/cl abxl (anyl abxl canl causel C.l Diff)
Nol antidiarrheal




Q:l Drugsl thatl promotel developmentl ofl C.l Diff

Answer:
cephalosporins,l clindamycin




Q:l Crossl sensitivityl forl penicillin

Answer:
cephalosporins




Q:l Penicillinl andl pregnancy

,Answer:
Okl tol takel whilel pregnant




Q:l Cephalosporinl patientl education

Answer:
patientsl shouldl reportl increasel inl stooll frequencyl d/tl riskl forl cl diff




Q:l Cephalosporinl andl pregnancy

Answer:
Cephalosporinsl arel ok




Q:l Tetracyclinel patientl education

Answer:
Tetra=4l (avoidl Milk,l Calcium,l Iron,l Magnesium)

Avoidl exposurel tol sunl orl tanningl beds

Manyl drugl interactionsl includingl digoxin




Q:l Tertracyclinel andl pregnancy

Answer:
Avoidl inl pregnancyl andl withl lactation

,Q:l Dol notl takel macrolidesl ifl (2l options)

Answer:
1l -l Dol notl takel withl prolongedl QT.l Whenl macrolidesl arel combinedl withl CYP3A4l
inhibitorsl (likel CCBl andl antifungals),l therel isl al fivefoldl increasel inl suddenl cardiacl
death.l

2l -l Macrolidesl inhibitl P450l enzymes,l whichl normallyl helpl metabolizel drugs.l Withoutl
theirl action,l therel isl al riskl forl drugl toxicityl withl theophylline,l carbamazepine,l andl
warfarin.




Q:l Whichl antibioticl inhibitsl CYP450l enzymesl andl increasesl levelsl ofl theophylline,l
warfarin,l andl carbamazepine?


Answer:
Macrolides




Q:l Aminoglycosidel patientl education

Answer:
patientsl shouldl reportl symptomsl ofl ototoxicity




Q:l Sulfonamidel patientl education

Answer:
drinkl 8-10l glassesl ofl waterl perl dayl tol preventl crystalluria

avoidl sunl andl tanning

, watchl forl hypersensitivityl syndromel (drugl reactionl whenl bodyl respondsl tol al drugl thel
wayl itl wouldl respondl tol anl infectionl -l Tl cellsl respondl andl therel canl bel damagel tol
organs)




Q:l Sulfonamidesl andl pregnancy

Answer:
birthl defectsl ifl takenl inl T1

kernicterusl riskl ifl givenl atl terml ANDl ifl givenl duringl lactationl tol infantl <2mol
(potentiallyl fatal,l causedl byl bilirubinl depositsl inl thel brainl -l bilirubinl isl neurotoxicl andl
canl causel severel neurologicall deficitsl andl death)




Q:l Renall adjustmentsl withl gentamicin

Answer:
decreasel dosel orl increasel intervall betweenl dosesl ifl concernl forl renall impairment




Q:l antimicrobiall sensitivityl testing

Answer:
labl testl tol determinel howl pathogensl growl whenl exposedl tol certainl drugsl inl al Petril
dishl (susceptible,l resistantl orl intermediate)




Q:l Considerationsl frol antibioticl treatment

Answer:
Hostl (patient)
Syndromel (illness)

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