NSG 533 EXAM 3
Ipratropium is also known as a (LAMA, SAMA, SABA, or LABA)
Short acting muscarinic antagonist (SAMA)
A muscarinic agonist would cause (bronchodilation or bronchoconstriction)?
Bronchoconstriction which is a vagal response.
A muscarinic antagonist would cause (bronchodilation or bronchoconstriction)?
Bronchodilation occurs when muscarinic receptors are blocked
What is another name for a muscarinic antagonist?
Anticholinergic
What is the mechanism of action (MOA) of ipratropium?
Blocks muscarinic receptors in the lung causing bronchodilation
, How is ipratropium administered?
The half- life is rather short and is given every 6 hours as needed. It is available as an
MDI and in nebulizer form. It is also available in a combination with albuterol as an
MDI and nebulized preparation
Why would a SAMA and a SABA be used together?
Dual action of bronchodilation occurs with stimulation of the beta2 receptors and
blocking of muscarinic receptors both of which lead to bronchodilation
Why is combining bronchodilators from different classes preferred especially in
patients with COPD?
It may improve efficacy and decrease the risk of side effects compared to increasing
the dose of a single bronchodilator
Is ipratropium used for asthma?
It is usually only used in the emergency room for asthma exacerbations
What are the advantages of using a long acting muscarinic antagonist (LAMA)
such as tiotropium (Spiriva) instead of ipratropium (Atrovent)?
Once a day dosing decreases exacerbations and increases adherence in patients
with COPD
Ipratropium is also known as a (LAMA, SAMA, SABA, or LABA)
Short acting muscarinic antagonist (SAMA)
A muscarinic agonist would cause (bronchodilation or bronchoconstriction)?
Bronchoconstriction which is a vagal response.
A muscarinic antagonist would cause (bronchodilation or bronchoconstriction)?
Bronchodilation occurs when muscarinic receptors are blocked
What is another name for a muscarinic antagonist?
Anticholinergic
What is the mechanism of action (MOA) of ipratropium?
Blocks muscarinic receptors in the lung causing bronchodilation
, How is ipratropium administered?
The half- life is rather short and is given every 6 hours as needed. It is available as an
MDI and in nebulizer form. It is also available in a combination with albuterol as an
MDI and nebulized preparation
Why would a SAMA and a SABA be used together?
Dual action of bronchodilation occurs with stimulation of the beta2 receptors and
blocking of muscarinic receptors both of which lead to bronchodilation
Why is combining bronchodilators from different classes preferred especially in
patients with COPD?
It may improve efficacy and decrease the risk of side effects compared to increasing
the dose of a single bronchodilator
Is ipratropium used for asthma?
It is usually only used in the emergency room for asthma exacerbations
What are the advantages of using a long acting muscarinic antagonist (LAMA)
such as tiotropium (Spiriva) instead of ipratropium (Atrovent)?
Once a day dosing decreases exacerbations and increases adherence in patients
with COPD
