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NSG 533 / NSG533 EXAM 2 MODULE 5. LIVER DISORDERS. QUESTIONS WITH 100% VERIFIED ANSWERS.

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What is the hypothesized role of adipose tissue in fatty liver disease? visceral fat releases signals that disrupt how the body handles glucose and fat leading to more fat being stored in the liver Excess fat in liver causes liver distress Why does liver damage occur from the hypothesized role of adipose tissue in liver disease? excess fat causes inflammation and the liver is unable to manage: fatty peroxidation dysregulation of unfolded protein lipotoxicity apoptotic pathways What is NAFLD? Non-alcoholic fatty liver disease, condition characterized by accumulation of fat int he liver cells not caused by alcohol consumption Conditions of diagnosis for NAFLD? evidence of fatty liver (imaging or histology) No causes for secondary fat accumulation such as: excess alcohol consumption use of steatogenic medication hereditary disorders Most common clinical manifestations in pads and adult patients usually asymptomatic, can remain undetected for years Steatosis: fat infiltration > 5% ballooning fatty deposits mild inflammation DM II/Insuling resistance Overweight/central obesity (also children) high levels of cholesterol and triglycerides metabolic syndrome Alterations in gut microbiome

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Uploaded on
January 20, 2025
Number of pages
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Written in
2024/2025
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Exam (elaborations)
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NSG 533 EXAM 2 MODULE 5
Hepatitis A: What to obtain for patient history
history of blood transfusion
msm
poor sanitation
travel to developing nations (contaminated food or water!)
exposure to an infected person
family history


True / False most cases of Hep A are symptomatic
TRUE


What cases of hep a are not symptomatic?
children under 6 years old (70% are symptomatic)


What are some clinical presentations for Hep A?
flu-like symptoms
fever
fatigue
loss of appetite
N/V/D
abd pain
dark urine
CLAY COLORED STOOLS
joint pain

,jaundice: cholestasis, hyperbilirubinemia
--Decreased albumin and prolonged PT--


Hepatitis B: What to obtain for patient history
75% positive cases in Asia
Hemodialysis
Multiple blood transfusions (esp internationally)
use of immunosuppressive drugs
Perinatal - HEP B status of pregnant mothers
multiple sex partners
household infection of HBV
occupational exposure
IVDU
Nosocomial


Is Hep B acute or chronic?
BOTH! Can be acute or chronic


What to look for (history) in acute Hep b infection?
exposure with infected blood or fluid within the past few months


What to look for (history) in chronic Hep B infection?
history of risk factors, serologic testing (+) for 6 months


Clinical Presentations of ACUTE Hep B

, FLU LIKE SYMPTOMS
general illness
anorexia
N/V
body aches
mild fever
dark urine
jaundice


Clinical presentations for chronic Hep B
CAN BE ASYMPTOMATIC
Prodromal period: mild symptoms appear
RUQ pain 2/2 hepatomegaly
fatigue
joint pain


Physical findings with HEP B?
hepatosplenomegaly
spider veins
jaundice
ascites
peripheral edema


How long is prodromal period of Hep B?
1-4 months


What is serum sickness in Hep B?

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