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T3 and T4 decreased, TSH increased - ✔✔ANSWER✔✔>>hypothyroidism
T3 T4 increased TSH decreased - ✔✔ANSWER✔✔>>hyperthyroidism
sensitivity to cold - ✔✔ANSWER✔✔>>check tsh (hypothyroidism)
sensitivity to heat - ✔✔ANSWER✔✔>>check tsh (hyperthyroidism)
urinalysis = 4+ proteinuria - ✔✔ANSWER✔✔>>lithium toxicity
neuroprotective for bipolar 1 disorder - ✔✔ANSWER✔✔>>lithium
NSAIDs, ACE inhibitors (-prils), thiazides - ✔✔ANSWER✔✔>>increase lithium levels by
decreasing renal clearance
lithium side effects - ✔✔ANSWER✔✔>>gi upset, tremors coars, t wave inversion,
hyponatremia
depakote - ✔✔ANSWER✔✔>>spina bifida, hepatotoxicity
do LFTs
right upper quadrant pain and dark urine
kava kava - ✔✔ANSWER✔✔>>stress and anxiety
causes hepatotoxicity, sedation (don't give with benzos)
do LFTs
can worsen depression
Lamictal - ✔✔ANSWER✔✔>>SJS (fever, rash, joint pain, headache, painful mucous
membranes)
Carbamezapine - ✔✔ANSWER✔✔>>SJS (fever, rash, joint pain, headache, painful
mucous membranes)
test HLAB 1502 allele in asians
agranulocytosis (ANC<1000 stop; also in clozaril)
,agranulocytosis - ✔✔ANSWER✔✔>>fever, chills, fatigue, sore throat
NMS and Serotonin Syndrome - ✔✔ANSWER✔✔>>NMS:
caused by antipsychotics
muscle rigidity
mutism
rhabdomyolisis
myoglobinuria
increased CPK, LFTs, WBCs (leukocytosis)
Serotonin Syndrome
caused by antidepressants
hyperreflexia
myoclonic jerks
treatment for NMS - ✔✔ANSWER✔✔>>bromocriptine as dopamine agonist (D2)
dantrolene as muscle relaxant
treatment for serotonin syndrome - ✔✔ANSWER✔✔>>Cyproheptadine (5-HT2 receptor
antagonist)
time frame to switch serotonin meds (MAOI)
(and fluoxetine?) - ✔✔ANSWER✔✔>>2 weeks
5 to 6 weeks with fluoxetine
antidepressant for cancer - ✔✔ANSWER✔✔>>citalopram and escitalopram
less drug to drug interactions
contraindication for wellbutrin - ✔✔ANSWER✔✔>>seizure d/o
eating d/o
antidepressant for low energy and fatigue - ✔✔ANSWER✔✔>>NDRI
wellbutrin
medications for neuropathy - ✔✔ANSWER✔✔>>SNRI/TCA
alpha 2 delta ligand (Gabapentin, lyrica)
what to ask when client is depressed (additional question) - ✔✔ANSWER✔✔>>alcohol
use
antidepressant efficacy time - ✔✔ANSWER✔✔>>4-6 weeks
Serotonin syndrome symptoms - ✔✔ANSWER✔✔>>hypertension, tachycardia;
myoclonic jerking, tremors;
nausea, diarrhea, sweating, hyperthermia;
, agitation, confusion
flu like symptoms
hypertensive crisis - ✔✔ANSWER✔✔>>Severe Headache
Palpitations
Diaphoretic
Stiff Neck
pupillary dilation
MAOI with tyramine - ✔✔ANSWER✔✔>>hypertensive crisis
treatment for hypertensive crisis - ✔✔ANSWER✔✔>>Phentolamine
schizophrenia age of onset - ✔✔ANSWER✔✔>>men 18-25
women 25-35
risk factors for schizophrenia - ✔✔ANSWER✔✔>>genetic loading - first degree relative
prenatal exposure to flu or virus
prenatal malnutrition or illness
obstetrical complications
CNS infection in childhood
substance use
oxygen deprivation
excessive pruning
inadequate formation
schizophrenia mri - ✔✔ANSWER✔✔>>ventricular enlargement
apoptosis - ✔✔ANSWER✔✔>>neuronal loss
cell death
conversion syndrome - ✔✔ANSWER✔✔>>neurological symptoms
parasthesia (pins and needles; tingling; numb)
mutism
paralysis
blindness
adjustment disorder - ✔✔ANSWER✔✔>>reaction to life event
anxiety, depression
usually after a loss
bipolar disorder - ✔✔ANSWER✔✔>>digfast (mnemonic)
distractibility
impulsivity
grandiosity