RAU’s Respiratory Care Pharmacology
j j j
9TH EDITIONj
BY GARDENHIRE
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TESTBANK j
,Description
TestjBankjforjRau’sjRespiratoryjCarejPharmacologyj9thjEditionjGardenhire
TestjBankjforjRau’sjRespiratoryjCarejPharmacology,j9thjEdition,jGardenhire,jISBN-
10:j0323299687,jISBN-13:j9780323299688
TablejofjContents
UnitjI:jBasicjConceptsjandjPrinciplesjinjPharmacology
1.jIntroductionjtojRespiratoryjCarejPharmacology
2.jPrinciplesjofjDrugjAction
3.jAdministrationjofjAerosolizedjAgents
4.jCalculatingjDrugjDoses
5.jThejCentraljandjPeripheraljNervousjSystems
UnitjII:jDrugsjUsedjtojTreatjthejRespiratoryjSystem
6.jAdrenergicj(Sympathomimetic)jBronchodilators
7.jAnticholinergicj(Parasympatholytic)jBronchodilators
8.jXanthines
9.jMucus-ControllingjDrugjTherapy
10.jSurfactantjAgents
11.jCorticosteriodsjinjRespiratoryjCare
12.jNonsteroidaljAntiasthmajAgents
13.jAerosolizedjAntiinfectivejAgents
14.jAntimicrobialjAgents
15.jColdjandjCoughjAgents
16.jSelectedjAgentsjofjPulmonaryjValue
17.jNeonataljandjPediatricjAerosolizedjDrugjTherapy
UnitjIII:jCriticaljCare,jCardiovascular,jandjPolysomnographyjAgents
18.jSkeletaljMusclejRelaxantsj(NeuromuscularjBlockingjAgents)
19.jDiureticjAgents
20.jDrugsjAffectingjthejCentraljNervousjSystem
21.jVasopressors,jInotropes,jandjAntiarrythmicjAgents
22.jDrugsjAffectingjCirculation:jAntihypertensives,jAntianginals,jAntithrombotics
23.jSleepjandjSleepjPharmacology
,Chapter 01: Introduction to Respiratory Care Pharmacology Gardenhire:
j j j j j j j j
Rau’s Respiratory Care Pharmacology, 9th Edition
j j j j j
MULTIPLEjCHOICE
1. Whatjisjthejnamejofjthejreceptorjsitesjthatjarejlocatedjinjthejperipheraljvasculature,jthejheart,jbronchialjmusc
le,jandjbronchialjbloodjvessels?
a. Betaj2jreceptors c. Alphajreceptors
b. Gammajreceptors d.jjj Betaj1jreceptors
ANS:j C
Alphajreceptorsjarejlocatedjinjthejperipheraljvasculature,jthejheart,jbronchialjmuscle,jandjbronchialjblood
jvessels.
PTS:j 1
2. Whichjreceptorjsitejresultsjinjtachycardia,janjincreasedjpotentialjforjarrhythmias,jandjanjincreasedjcard
iacjoutput?
a. Betaj1jreceptor c. Alphajreceptor
b. Betaj2jreceptor d.j Deltajreceptor
ANS:j A
Stimulationjofjthejbeta-
1jreceptorsjresultsjinjtachycardia,janjincreasedjpotentialjforjarrhythmias,jandjanjincreasedjcardiacjoutput.j
Injadministeringjdrugsjtojthejpulmonaryjsystem,jstimulationjofjthejbeta-
1jsitesjisjnotjdesired.jHowever,jmostjrespiratoryjpharmacologicjagentsjhavejsomejbeta-
1jstimulatoryjeffect.
PTS:j 1
3. Stimulationjofjthejbetaj2jreceptorsjcausesjj
a. peripheraljvasoconstrictionjandjmildjbronchoconstrictionjinjthejlungs.
b. tachycardia,janjincreasedjpotentialjforjarrhythmias,jandjanjincreasedjcardiacjoutput.
c. bronchodilation.
d. peripheraljvasodilation,jbradycardia,jandjdecreasedjcardiacjoutput.
ANS:j C
Stimulationjofjthejbeta-2jreceptorsjinjthejlungsjcausesjbronchodilation.
PTS:j 1
4. Acetylcholinejstimulatesjj
a. thejVagusjnerve.
b. thejadrenergicjreceptors.
c. thejsympatheticjnervousjsystem.
d. thejcholinergicjreceptors.
ANS:j D
Acetylcholinejstimulatesjthejcholinergicjreceptors.
PTS:j 1
5. Whatjimmunoglobulinjantibodyjsensitizesjthejmastjcell?
a. Leukotrienes c. Histamine
, b. IgE d.j Prostaglandins
ANS:j B
ThejIgEj(reagin)jantibodiesjsensitizejthejmastjcell.jRepeatedjexposurejtojthejantigenjcausesjthejdegra
nulationjofjthejmastjcell.
PTS:j 1
6. Whichjofjthejfollowingjisjcausedjbyjhistaminejreleasejfromjthejmastjcells?
I. Bronchodilation
II. Increasedjbronchialjglandjsecretion
III. Increasedjamountjofjmucusjpresentjinjthejairways
a. IjandjIIjonly c. IIIjonly
b. IIjandjIIIjonly d.jjj I,jII,jIII
ANS:j B
Histaminejisjalsojajpotentjbronchoconstrictor.jInjadditionjtojitsjbronchoconstrictivejactivity,jhistamine
II)jincreasesjbronchialjglandjsecretion,jcausingjIII)janjincreasejinjthejamountjofjmucusjpresentjinjt
hejairways.jHistaminejmayjalsojhavejanjeffectjonjvascularjpermeabilityjsimilarjtojthejeffectjof-jSRS-A.
PTS:j 1
7. Ajsympathomimeticjdrugjwouldjcausejj
a. bronchodilation. c. Histaminejrelease.
b. bronchoconstriction. d.jVagusjnervejstimulation.
ANS:j A
Ajsympathomimeticjdrugjwouldjcausejbronchodilation.jSympathomimeticjagentsjarejthejdrugsjmostjcommonlyj
usedjtojreversejbronchospasm.
PTS:j 1
8. Stimulationjofjthejsympatheticjnervousjsystemjcausesjj
a. vascularjpermeability. c. bronchodilation.
b. decreasedjbloodjpressure. d.j bronchoconstriction.
ANS:j C
Sympatheticjnervousjsystemjstimulationjcausesjbronchodilation.
PTS:j 1
9. WhichjofjthejfollowingjwouldjNOTjcausejajbronchospasmjorjbronchoconstriction?
a. Leukotrienes c. Histamine
b. Betaj1jreceptors d.j Prostaglandins
ANS:j B
Beta-
1jreceptorsjwouldjnotjcausejajbronchospasmjorjbronchoconstriction.jLeukotrienesjarejonejofjmanyjch
emicaljmediatorsjreleasedjbyjthejmastjcells.jLeukotrienesjcausejajdirect,jstrongjbronchoconstriction.jHista
minejisjalsojajpotentjbronchoconstrictor.jProstaglandinsjcausejajstrongjbronchospasm,jespeciallyjinjasthm
aticjpatients.
PTS:j 1