Test Bank For Modern Blood Banking & Transfusion Practices 7th Edition By Denise M Harmening 9780803668881 Chapter 1-29 Complete Guide .

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TEST BANK FOR MODERN BLOOD BANKING
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& TRANSFUSION PRACTICES 7TH EDITION
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BY DENISE M HARMENING
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9780803668881 CHAPTER 1-29 COMPLETE
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GUIDE mm

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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choicemm



Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis
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b. Luebering-Rapoport shunt d. Methemoglobin reductase mm m m mm




2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV
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failed. The unit of blood was outside the blood bank for 35 minutes. Which of the statements
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below is most accurate?
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a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm mm mm c. 1 to 2 µm
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b. 2 to 4 µm mm mm d. mm 4 to 6 µm m m m m mm mm mm




4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the
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tissues when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% m m




5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count
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b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear
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as a result of loss of RBC membrane?
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a. Spherocytes c. Burr cells mm



b. Target cells d. mm Schistocytes m m




7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend
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c. An individual donating blood for a relative
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d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism mm c. Oxygen transport mm



b. Porphyrin synthesis d. Signal transduction
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. mm d. Hemoglobin structure. m m mm




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m m 10. m m What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate
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b. 40% protein, 8% lipid, 52% carbohydrate
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c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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m m 11. m m All of the following biochemical changes are associated with loss of red blood cell viability upon
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storage
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except:
a. Decreased pH. mm c. Increased ATP level. mm mm



b. Loss of red blood cell function.
mm mm mm mm mm d. Decreased glucose consumption.
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m m 12. m Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD m m m m




m m 13. m The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. m m




m m 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released
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from the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% m m m m




m m 15. m What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d. Regulation of pH
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m m 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical
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signs of alkalosis?
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a. Normal c. Shift to the right mm mm mm



b. Shift to the left mm d. None of the above
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m m 17. m Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A m m mm




m m 18. m The ABO blood groups were discovered in 1901 by whom?
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a. Charles Drew c. Loutit and Mollison
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b. Karl Landsteiner mm d. Edward Lindeman m m mm




m m 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently
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left in the corner of the department until discovered 36 hours later. What would the appropriate
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action be for the blood banker?
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a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it
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would be OK to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The unit
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should be discarded because the pH has probably dropped too low and platelet
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activation has been compromised.
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c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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accept the unit into inventory.
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d. If the platelets appeared OK and passed the platelet swirl test after being placed
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on the agitator, they could be accepted into the inventory.
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m m 20. m Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
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a. Glycolysis c. Pentose phosphate shunt mm mm



b. Luebering-Rapoport shunt d. Methemoglobin reductase mm m m mm




m m 21. m m All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation
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curve
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except:
a. Increased 2,3-DPG. mm


b. 50% O2 saturation to tissues.
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c. Decreased 2,3-DPG. mm



d. Decreased hemoglobin affinity for O2. mm mm mm mm




m m 22. m What is the normal platelet count range per cubic millimeter?
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a. 100 to 350 mm mm c. 50,000 to 200,000 mm mm



b. 150,000 to 350,000 mmd. 350,000 to 500,000
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m m 23. m What cryoprotective agent is added to red blood cells upon freezing?
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a. Dextrose c. Glycerol
b. Adsol d. All of the above m m mm mm mm




m m 24. m If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
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a. 1°C to 6°C mm mm c. 35°C to 37°C mm mm



b. 20°C to 24°C mm mm d. 1°C to 10°C m m mm mm




m m 25. m m What role do platelets play in hemostasis?
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a. Maintenance of vascular integrity mm mm mm



b. Initial arrest of bleeding by platelet plug formation
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c. Stabilization of the hemostatic plug mm mm mm mm



d. All of the above
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m m 26. m m Which of the following best describes "integral" membrane proteins?
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a. Reside at the cytoplasmic surface of membrane
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b. Span the entire membrane surface
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c. Form the red blood cell cytoskeleton
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d. None of the abovemm mm mm




m m 27. m m How is stroma-free
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a. Outdated red blood mm mm mm cells are concentrated, and stroma is removed.
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b. Outdated red blood mm mm mm cells are diluted with saline, and stroma is removed.
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c. Outdated red blood mm mm mm cells are lysed, and stroma is removed.
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d. None of the abovemm mm mm




m m 28. m What is the normal life span of an RBC?
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a. 100 days mm c. 120 hours mm



b. 120 days mm d. 2 days m m mm




m m 29. m Regarding loss of RBC membrane deformability, all of the following are true except:
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a. Increase in ATP level. mm mm mm



b. Decrease in ATP level. mm mm mm




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