,TEST BANK FOR MODERN BLOOD BANKING &
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TRANSFUSION PRACTICES 7TH EDITION BY
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DENISE M HARMENING
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9780803668881 CHAPTER 1-29 COMPLETE
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GUIDE xx
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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice xx
Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis xx xx
b. Luebering-Rapoport shunt d. Methemoglobin reductase xx x x xx
2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
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The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
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accurate? xx
a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm xx xx xx c. 1 to 2 µm xx xx xx
b. 2 to 4 µm xx xx xx d. 4 to 6 µmx x x x xx xx xx
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the
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tissues when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% x x
5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count xx xx
b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
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result of loss of RBC membrane?
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a. Spherocytes c. Burr cells xx
b. Target cells d. Schistocytes xx x x
7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend
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c. An individual donating blood for a relative
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d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism c. Oxygen transport
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b. Porphyrin synthesis d. Signal transduction xx x x xx
9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
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x x 10. What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate xx xx xx xx xx
b. 40% protein, 8% lipid, 52% carbohydrate xx xx xx xx xx
c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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x x 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level. xx xx xx
b. Loss of red blood cell function. d. Decreased glucose consumption.
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x x 12. Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD x x x x
x x 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. x x
x x 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
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the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% x x x x
x x 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d. Regulation of pH
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x x 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
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of alkalosis?
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a. Normal c. Shift to the right xx xx xx
b. Shift to the left d. None of the above
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x x 17. Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A x x xx
x x 18. The ABO blood groups were discovered in 1901 by whom?
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a. Charles Drew c. Loutit and Mollison
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b. Karl Landsteiner d. Edward Lindeman
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x x 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
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the corner of the department until discovered 36 hours later. What would the appropriate action be for the
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blood banker?
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a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would
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be OK to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has
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been compromised.
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c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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