v v v v v v v
TH EDITION KOEPPEN ALL CHAPTERS 1-44
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COMPLETE GUIDE (NEWEST VERSION) 2024. v v v v
Berne and Levy Physiology 7th Edition KoeppenTest Bank
v v v v v v v
Koeppen: Berne and Levy Physiology, 7th Edition
v v v v v v
Chapter 01: Principles of Cell
v v v v
FunctionTest Bank Multipl v v
e Choice
v
1.vThesubcellularstructurethatdegradesproteinsiscalledthe:
A. Tightjunction
B. Mitochondria
C. Lysosome
D. Plasmamembrane
E. Ribosome
ANS:vC
2.vAnexperimentisdonetomeasuretheuptakeofanaminoacidintoacell.Thefollowingvdataareobtained:
N v
IfNa+ isremovedfromtheextracellularbathingsolution,orifadrugisaddedthatpreventsthevcellfrommakingadeno
v
sinetriphosphate(ATP),theuptakeofaminoacidintothecellisvmarkedlyreduced.Accordingtothisinformation,wh
ichofthefollowingmechanismsisvprobablyresponsibleforthetransportoftheaminoacidintothecell?
A. Passivediffusionthroughthelipidbilayer
B. Uniporter
C. TransportATPase
D. Na+ symporter
v
E. Na+antiporter
ANS:vD
3.vAmembranepermeablebyonlyNa+separatestwocompartmentscontainingvNa2SO4,shownasfollows:
,BerneandLevyPhysiology7thEditionKoeppenv
Electrodesareplacedinbothcompartments,andavoltageisapplied(thatofcompartmentAisvheldat0mV).Whatvol
tageappliedtocompartmentBwouldresultinvnovnetmovementofNa+ acrossthemembraneseparatingthecompart
v
ments?
A. –60mV
B. –30mV
C. 0mV
D. +30mV
E. +60mV
ANS:vE
R N G
4.vTherestingmembranepotentvNiaUlro efiSandIcice altle diTsin–
B8th5.emCfoVll.oTwhienginttraabcleel,lualsarisanthdeexcatrlaccuellaluteladr concentrationsofse
v
veralionsa
Nernstequilibriumpotential(Ei)foreachoftheseions:
Ion ConcentrationvInsideCell ConcentrationvOutsideCell Ei
Na+ 12mEq/L 145mEq/L 66mV
K+ 150mEq/L 4mEq/L –96mV
Cl– 30mEq/L 105mEq/L –33mV
Ca++ 0.0001mmol/dL 1mmol/dL 122mV
ThemembranehaschannelsforNa+,K+,Cl–
,andCa++.Theconductanceofthevmembraneisthegreatestforwhichion?
A. Na+
B. K+
C. Cl– D.vCa++
v
ANS:B
5. Acellcontainsthefollowingmembranetransporters:
,BerneandLevyPhysiology7thEditionKoeppenv
Na+channelK+channel
Na+,K+-ATPase
Therestingmembranevoltageofthecellis–
80mV,andtheintracellularandvextracellularionconcentrationsareasfollows:
Ion IntracellularvConcentration ExtracellularvConcentration
Na+ 10mEq/L 145mEq/L
K+ 120mEq/L 4mEq/L
ThecellistreatedwithadrugtoinhibittheNa+,K+-
ATPase.Whatwouldbetheeffectofthisdrugvonthefollowingparameters?
Intracellular[Na+] Intracellular[K+] CellVolume MembraneVoltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase Nochange
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS:vB
6. Whichofthelabeledproteins(shaded)isattachedtothemembranebyavglycosylphosphatidylinositol(GPI)
anchor?
ANS:vE
7.AcellhaschannelsforNa+,K+,andCl–initsplasmamembrane.Therestingmembranevpotentialis–
60mV(cellinteriornegative).Theintracellularandextracellularvconcentrationsfortheseions,asw
ellasthecalculatedNernstpotentials,arelistedasvfollows:
Ion IntracellularvConcentration ExtracellularvConcentration Ei
Na+ 14mEq/L 140mEq/L 60mV
K+ 150mEq/L 5mEq/L –89mV
Cl– 10mEq/L 100mEq/L –60mV
AdrugisappliedtothecellthatincreasesthepermeabilityofthecellbyCl (i.e.,itopensCl–
– v
channels).WhateffectwillthisdrughaveonthenetmovementofCl– acrosstheplasmavmembrane?
v v
, BerneandLevyPhysiology7thEditionKoeppenv
A. NetCl– movementoutofthecellwillbeincreased.
v
B. NetCl– movementintothecellwillbeincreased.
v
C. TherewillbenochangeinthenetmovementofCl–.
ANS:vC
8. Reducingtheextracellular[K+]wouldbeexpectedtohavewhichofthefollowingveffectsontherestingmem
branepotentialandontheexcitabilityofventricularvmyocytes?
MembranePotential Excitability
A. Unchanged Unchanged
B. Hyperpolarized GDTecBre.aCseOd
C. Hyperpolarized Increased
D. Depolarized Decreased
E. Depolarized Increased
ANS:vB
9. AcellisbathedinanisotonicNaClsolutionthatcontains5mmol/Lofglucose.Thevintracellularconcentratio
nofglucoseis10mmol/L.Whatisthemostlikelymechanismvforthetransportofglucoseacrosstheplasmam
embraneintothiscell?
A. Glucoseuniporter
B. Na+-glucosesymporter
C. Na+-glucoseantiporter
D. Diffusionofglucosethroughthelipidbilayerofthemembrane
ANS:vB
10. Abloodsampleistakenfromanindividualwhosebloodosmolalityis295mOsmpervkilogramofwater.Redb
loodcellsfromthissamplearethenplacedinthefollowingvsolutions:
1-5
Solution Osmolality(mOsm/kgH2O) Reflection
Coefficient
( vof
Solute
1. NaCl 300 1
2. Fructose 300 0.5
3. Urea 300 0
4. CaCl2 100 1
5. KCl 150 1
Theredbloodcellsinwhichofthesesolutionswillswelltothegreatestdegree?