Advanced Pharmacology: Midterm Exam
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80% of patients with PUD test positive for what?-CORRECT ANSWERS-H Pylori
A benzodiazepine hypnotic drug is?-CORRECT ANSWERS-Flurazepam, Temazepam, or Triazolam
A nonbenzodiazepine hypnotic drug is?-CORRECT ANSWERS-Zolpiden or Eszopiclone
AA and Asians have a 3-4 times greater risk of developing ____________?-CORRECT ANSWERS-
Angioedema
Absolute refractory period is ________-CORRECT ANSWERS-Regardless of the strength of a stimulus, the
cell cannot be depolarized.
absorption-CORRECT ANSWERS-movement of drug from site of administration into blood
Acarbose-CORRECT ANSWERS-Class: Alpha Glucosidase Inhibitor; third-line for DM2 in insulin resistant
patients
MOA: Inhibits absorption of CHO in GI, lowers BG levels after meals
Acebutolol-CORRECT ANSWERS-Class: Beta Adrenergic Blockers
MOA: Has ISA, may help avoid a decrease in CO and HR, may be preferred for patients who experience
bradycardia with other BB.
ACEI for angina-CORRECT ANSWERS-decrease afterload
reduce aldosterone
active transport-CORRECT ANSWERS-moves against concentration gradient, uses ATP
Affinity-CORRECT ANSWERS-increased ________ = increased tightness of binding
Agonist-CORRECT ANSWERS-causes a change; fully activates 2nd messenger system
Albumin-CORRECT ANSWERS-primary blood protein
Alendronate-CORRECT ANSWERS-Class: Bisphosphanate used to treat osteoporosis and Paget's dx
,MOA: Inhibits osteoclastic activity, increases bone density.
All laxatives are contraindicated in the presence of what?-CORRECT ANSWERS-Nausea, vomiting or
undiagnosed abdominal pain
Almost 100% in 3 month olds have what?-CORRECT ANSWERS-Pediatric GER
alpha 1 receptors-CORRECT ANSWERS-nasal congestion, hypotension, dilation of pupils
alpha 2 receptors-CORRECT ANSWERS-hypertension
Alprazolam, Lorazepam-CORRECT ANSWERS-class: anxiolytics
rapid onset
increase GABA
Amiodorone-CORRECT ANSWERS-Class: Potassium Channel Blocker
MOA: Prolongs the effective refractory period ERP) and duration of the action potential, reduces speed
of conduction; long onset 2 days-3 weeks
amitriptyline-CORRECT ANSWERS-class: tricyclic antidepressants
insomnia, depression, neuropathic pain
Amlodipine-CORRECT ANSWERS-Class: Calcium Channel Blocker; Type 2
MOA: Does NOT affects the conduction through the AV node; vasodilator, lowers calcium influx into
smooth muscles.
An anticonvulsant used in the treatment of tonic clonic or partial complex seizures?-CORRECT
ANSWERS-Ethotoin or Phenytoin
anesthesia and volume of distribution-CORRECT ANSWERS-anesthesia is lipophilic, absorbs into fat,
takes longer to excrete
Angiotensin comes from the __________-CORRECT ANSWERS-Liver
Antagonist-CORRECT ANSWERS-blocks a change; do not activate 2nd messenger system
Aspart-CORRECT ANSWERS-Class: Rapid acting insulin for hyperglycemia
MOA: Onset 5 minutes; peaks 5 minutes; duration 4-5 hours
Aspirin for angina-CORRECT ANSWERS-decrease platelet aggregation, prevent vasoconstriction and
platelet buildup
Atenolol-CORRECT ANSWERS-Class: Beta Adrenergic Blockers
MOA: Does not have ISA, preferred for post MI patients
atenolol-CORRECT ANSWERS-class: selective beta blocker
Atropine-CORRECT ANSWERS-class: cholinergic blocker
, prototype
Automaticity is ______________-CORRECT ANSWERS-Ability of heart cell to spontaneously depolarize
and generate an action potential. Can be altered, enhanced or decreased by cell damage, biochemical
disturbances, pharmacological agents and environmental factors.
Before treating osteoporosis, what other disorders would you consider that may cause low bone
density?-CORRECT ANSWERS-Hyperparathyroidism, hyperthyroidism, renal disease, or vitamin D
deficiency
Belladona-CORRECT ANSWERS-atropine
dilates pupils
acts on muscarinic-cholingeric receptors (antagonizes)
Benztropine-CORRECT ANSWERS-class: cholinergic blocker
add to carbidopa/levodopa for EPS symptoms
beta 1 receptors-CORRECT ANSWERS-cardiac arrest, heart failure, shock
beta 2 receptors-CORRECT ANSWERS-asthma, premature labor contractions
Beta Blocker-CORRECT ANSWERS-For angina; decrease contractility, heart rate conduction velocity, and
afterload
decrease MOD, decrease anginal pain
beta blockers can lead to ______-CORRECT ANSWERS-inability to detect hypoglycemia
Bethanechol-CORRECT ANSWERS-class: cholinergic drug
increases gastric tone, causes bladder contractions
use: neurogenic bladder
Bioavailability of a drug is altered by _____? (3)-CORRECT ANSWERS-Motility (digestive disorders), first
pass effect, enterohepatic recycling.
bioequivalence-CORRECT ANSWERS-determines if 2 drugs will have the same effect
Bioequivalence-CORRECT ANSWERS-will two drugs have the same physiologic effects (name brand vs.
generic)
Bisacodyl-CORRECT ANSWERS-Class: Laxative; stimulant
MOA: Direct action on intestinal mucosa by stimulating the myenteric plexus
Bismuth Subsalicylate-CORRECT ANSWERS-Class: Antidiarrheal; absorbent
MOA: Antisecretory, antimicrobial, and antiinflammatory effects
BP =-CORRECT ANSWERS-CO X PR
Questions with Approved
Answers Latest Update Graded A+,
Download to get Perfect
Score
80% of patients with PUD test positive for what?-CORRECT ANSWERS-H Pylori
A benzodiazepine hypnotic drug is?-CORRECT ANSWERS-Flurazepam, Temazepam, or Triazolam
A nonbenzodiazepine hypnotic drug is?-CORRECT ANSWERS-Zolpiden or Eszopiclone
AA and Asians have a 3-4 times greater risk of developing ____________?-CORRECT ANSWERS-
Angioedema
Absolute refractory period is ________-CORRECT ANSWERS-Regardless of the strength of a stimulus, the
cell cannot be depolarized.
absorption-CORRECT ANSWERS-movement of drug from site of administration into blood
Acarbose-CORRECT ANSWERS-Class: Alpha Glucosidase Inhibitor; third-line for DM2 in insulin resistant
patients
MOA: Inhibits absorption of CHO in GI, lowers BG levels after meals
Acebutolol-CORRECT ANSWERS-Class: Beta Adrenergic Blockers
MOA: Has ISA, may help avoid a decrease in CO and HR, may be preferred for patients who experience
bradycardia with other BB.
ACEI for angina-CORRECT ANSWERS-decrease afterload
reduce aldosterone
active transport-CORRECT ANSWERS-moves against concentration gradient, uses ATP
Affinity-CORRECT ANSWERS-increased ________ = increased tightness of binding
Agonist-CORRECT ANSWERS-causes a change; fully activates 2nd messenger system
Albumin-CORRECT ANSWERS-primary blood protein
Alendronate-CORRECT ANSWERS-Class: Bisphosphanate used to treat osteoporosis and Paget's dx
,MOA: Inhibits osteoclastic activity, increases bone density.
All laxatives are contraindicated in the presence of what?-CORRECT ANSWERS-Nausea, vomiting or
undiagnosed abdominal pain
Almost 100% in 3 month olds have what?-CORRECT ANSWERS-Pediatric GER
alpha 1 receptors-CORRECT ANSWERS-nasal congestion, hypotension, dilation of pupils
alpha 2 receptors-CORRECT ANSWERS-hypertension
Alprazolam, Lorazepam-CORRECT ANSWERS-class: anxiolytics
rapid onset
increase GABA
Amiodorone-CORRECT ANSWERS-Class: Potassium Channel Blocker
MOA: Prolongs the effective refractory period ERP) and duration of the action potential, reduces speed
of conduction; long onset 2 days-3 weeks
amitriptyline-CORRECT ANSWERS-class: tricyclic antidepressants
insomnia, depression, neuropathic pain
Amlodipine-CORRECT ANSWERS-Class: Calcium Channel Blocker; Type 2
MOA: Does NOT affects the conduction through the AV node; vasodilator, lowers calcium influx into
smooth muscles.
An anticonvulsant used in the treatment of tonic clonic or partial complex seizures?-CORRECT
ANSWERS-Ethotoin or Phenytoin
anesthesia and volume of distribution-CORRECT ANSWERS-anesthesia is lipophilic, absorbs into fat,
takes longer to excrete
Angiotensin comes from the __________-CORRECT ANSWERS-Liver
Antagonist-CORRECT ANSWERS-blocks a change; do not activate 2nd messenger system
Aspart-CORRECT ANSWERS-Class: Rapid acting insulin for hyperglycemia
MOA: Onset 5 minutes; peaks 5 minutes; duration 4-5 hours
Aspirin for angina-CORRECT ANSWERS-decrease platelet aggregation, prevent vasoconstriction and
platelet buildup
Atenolol-CORRECT ANSWERS-Class: Beta Adrenergic Blockers
MOA: Does not have ISA, preferred for post MI patients
atenolol-CORRECT ANSWERS-class: selective beta blocker
Atropine-CORRECT ANSWERS-class: cholinergic blocker
, prototype
Automaticity is ______________-CORRECT ANSWERS-Ability of heart cell to spontaneously depolarize
and generate an action potential. Can be altered, enhanced or decreased by cell damage, biochemical
disturbances, pharmacological agents and environmental factors.
Before treating osteoporosis, what other disorders would you consider that may cause low bone
density?-CORRECT ANSWERS-Hyperparathyroidism, hyperthyroidism, renal disease, or vitamin D
deficiency
Belladona-CORRECT ANSWERS-atropine
dilates pupils
acts on muscarinic-cholingeric receptors (antagonizes)
Benztropine-CORRECT ANSWERS-class: cholinergic blocker
add to carbidopa/levodopa for EPS symptoms
beta 1 receptors-CORRECT ANSWERS-cardiac arrest, heart failure, shock
beta 2 receptors-CORRECT ANSWERS-asthma, premature labor contractions
Beta Blocker-CORRECT ANSWERS-For angina; decrease contractility, heart rate conduction velocity, and
afterload
decrease MOD, decrease anginal pain
beta blockers can lead to ______-CORRECT ANSWERS-inability to detect hypoglycemia
Bethanechol-CORRECT ANSWERS-class: cholinergic drug
increases gastric tone, causes bladder contractions
use: neurogenic bladder
Bioavailability of a drug is altered by _____? (3)-CORRECT ANSWERS-Motility (digestive disorders), first
pass effect, enterohepatic recycling.
bioequivalence-CORRECT ANSWERS-determines if 2 drugs will have the same effect
Bioequivalence-CORRECT ANSWERS-will two drugs have the same physiologic effects (name brand vs.
generic)
Bisacodyl-CORRECT ANSWERS-Class: Laxative; stimulant
MOA: Direct action on intestinal mucosa by stimulating the myenteric plexus
Bismuth Subsalicylate-CORRECT ANSWERS-Class: Antidiarrheal; absorbent
MOA: Antisecretory, antimicrobial, and antiinflammatory effects
BP =-CORRECT ANSWERS-CO X PR
