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JANEWAY'S IMMUNOBIOLOGY 9TH EDITION
CHAPTER 1-2 QUESTIONS AND CORRECT
DETAILED ANSWERS 2025-2026 (VERIFIED
ANSWERS) ||ALREADY GRADED A+||NEWEST
VERSION
Immunological Memory ANS: The capacity of the immune system to make quicker
and stronger adaptive immune responses to successive encounters with an antigen.
Immunological memory is specific for a particular antigen and is long-lived.
The Two Major Lymphocytes? ANS: T cells and B cells
B-Cell Antigen Receptor (BCR) ANS: Formed by the same genes as antibodies
(immunoglobulins, Ig). Also known as membrane immunoglobulin (mIg) or surface
immunoglobulin, (sIg). The molecule is composed of two identical heavy chains and two
identical light chains. Each light and heavy chain have a constant and variable region. the
variable region of the heavy and light chain combine to form the antigen-binding site.
Plasma Cells ANS: Develop from B cells following binding of an antigen to its B-Cell
Antigen Receptor. They secrete antibodies that have the same receptor specificity.
T-Cell Antigen Receptor (TCR) ANS: Structure is related to immunoglobulins but is
also distinct. It is composed of two chains, TCR alpha and beta chains. They have a variable
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region and a constant region. The combination of the alpha and beta chain variable regions
creates a SINGLE binding site.
Effector T Lymphocytes ANS: Develops after T cells encounter an antigen. There are
three types: Cytotoxic, Helper & Regulatory.
Cytotoxic T Cells ANS: T cells, often called killer cells because of their capability to kill
invading organisms bearing the correct antigen.
Helper T Cells ANS: Lymphocytes that provide signals in the form of cytokines that
activate functions of other immune cells such as B-cell production of antibodies and
macrophage phagocytosis.
Regulatory T Cells ANS: Lymphocytes that suppress the activity of other lymphocytes
and help to limit the possible damage of immune responses.
Memory Cells ANS: General term for lymphocytes that are responsible for
immunological memory and protective immunity. They can rapidly differentiate into effector
cells upon second exposure.
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