MCB5252 Exam#2 Practice
Questions With Answers
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or
developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
D) Antibodies can bind to the surface of bacteria, but they cannot directly
lyse them - ANSWER B) Acquired (Secondary) immune deficiency is the result
of genetic or developmental defects
Which of the following is NOT TRUE of antigens?
A) Haptens become antigenic if they bind to larger carrier molecules
B) Antigens have size restriction and should be large enough for the immune
system to detect them
C) Polysaccharides are the most antigenic of all polymers
D) Antigens could be found on the surface of bacteria - ANSWER C)
Polysaccharides are the most antigenic of all polymers
Antigens presenting cells (APC's) process by__cells, and present antigens
to__cells.
A) Macrophage/Neutrophilis
,B) B cells/ Helper T Cell
C) Helper T cells/ plasma cell
D) Cytotoxic T Cells/ Macrophages - ANSWER B) B cells/ Helper T Cell
Which of the following DOES NOT apply to attenuated vaccines?
A) Attenuated vaccines require multiple doses because they possess few
antigenic determinants
B) Attenuated vaccines grow and cause mild infections
C) Attenuated vaccines provide herd immunity
D) Attenuated vaccines should not be given to pregnant women - ANSWER
A) Attenuated vaccines require multiple doses because they possess few
antigenic determinants
Bacteria food poisoning(intoxication)
A) Has shorter incubation period than bacterial infections.
B) is the result of ingestion of pre-formed toxins already present in food.
C) Is the result of ingestion of bacterial endospores already present in food
A and B
B and C - ANSWER A and B
Which of the following would be the most effective against intracellular
pathogens?
A. Cell-mediated immunity (CMI)
B. Complement fixation via alternate pathway
,C. Complement fixation via classical pathway
D. Antibody-mediated immunity (AMI) - ANSWER A. Cell-mediated immunity
(CMI)
Which of the following classes of antibodies does NOT match with its
function?
A. All of them match
B. IgE→ involved in allergic reactions
C. IgG→ major circulating antibody
D. IgA→ major antibody in secretions - ANSWER A. All of them match
Regular injection of allergen over a period of time helps patient overcome
severe allergic reactions. This is known as desensitization. Desensitization
involves the gradual drop in IgE and rise of IgG titer in serum.
A. True
B. False - ANSWER A. True
ELISA is an immunological test that can do all of the these except:
A. Measure the amount (liter) of HIV in a blood sample
B. ELISA can do ALL of these
C. Detect if someone has produced antibody in response to HIV infection
D. Detect if someone is infected with HIV - ANSWER B. ELISA can do ALL of
these
When one compares the antibody mediated immunity (AMI) and Cell
, mediated immunity (CMI), one notices all of the following except:
A. All of these statements apply
B. Both AMI and CMI are components of the specific immunity
C. Both involved memory cells (Antibody has it, cell does have it I think)
D. CMI is involved in killing cancer and tumor cells
E. Only AMI is involved in classical pathway for complement fixation -
ANSWER E. Only AMI is involved in classical pathway for complement
fixation
Graft vs host disease occurs when graft cells attack the recipient tissue.
Which of the following statements apply to it?
A. Disease occurs when MHC I on donor tissue does not match with MHC I on
recipient tissue
B. Both are true
C. Disease occurs following bone marrow transplant
D. Neither are true - ANSWER B. Both are true
Immune complex is formed when antigen and antibody bind. Formation of
this complex result in all of the following except:
A) All of these are the consequences of formation of the antigen-antibody
complex
B) Complement fixation via classical pathway
C) Opsonization and marking bacteria for destruction
Questions With Answers
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or
developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
D) Antibodies can bind to the surface of bacteria, but they cannot directly
lyse them - ANSWER B) Acquired (Secondary) immune deficiency is the result
of genetic or developmental defects
Which of the following is NOT TRUE of antigens?
A) Haptens become antigenic if they bind to larger carrier molecules
B) Antigens have size restriction and should be large enough for the immune
system to detect them
C) Polysaccharides are the most antigenic of all polymers
D) Antigens could be found on the surface of bacteria - ANSWER C)
Polysaccharides are the most antigenic of all polymers
Antigens presenting cells (APC's) process by__cells, and present antigens
to__cells.
A) Macrophage/Neutrophilis
,B) B cells/ Helper T Cell
C) Helper T cells/ plasma cell
D) Cytotoxic T Cells/ Macrophages - ANSWER B) B cells/ Helper T Cell
Which of the following DOES NOT apply to attenuated vaccines?
A) Attenuated vaccines require multiple doses because they possess few
antigenic determinants
B) Attenuated vaccines grow and cause mild infections
C) Attenuated vaccines provide herd immunity
D) Attenuated vaccines should not be given to pregnant women - ANSWER
A) Attenuated vaccines require multiple doses because they possess few
antigenic determinants
Bacteria food poisoning(intoxication)
A) Has shorter incubation period than bacterial infections.
B) is the result of ingestion of pre-formed toxins already present in food.
C) Is the result of ingestion of bacterial endospores already present in food
A and B
B and C - ANSWER A and B
Which of the following would be the most effective against intracellular
pathogens?
A. Cell-mediated immunity (CMI)
B. Complement fixation via alternate pathway
,C. Complement fixation via classical pathway
D. Antibody-mediated immunity (AMI) - ANSWER A. Cell-mediated immunity
(CMI)
Which of the following classes of antibodies does NOT match with its
function?
A. All of them match
B. IgE→ involved in allergic reactions
C. IgG→ major circulating antibody
D. IgA→ major antibody in secretions - ANSWER A. All of them match
Regular injection of allergen over a period of time helps patient overcome
severe allergic reactions. This is known as desensitization. Desensitization
involves the gradual drop in IgE and rise of IgG titer in serum.
A. True
B. False - ANSWER A. True
ELISA is an immunological test that can do all of the these except:
A. Measure the amount (liter) of HIV in a blood sample
B. ELISA can do ALL of these
C. Detect if someone has produced antibody in response to HIV infection
D. Detect if someone is infected with HIV - ANSWER B. ELISA can do ALL of
these
When one compares the antibody mediated immunity (AMI) and Cell
, mediated immunity (CMI), one notices all of the following except:
A. All of these statements apply
B. Both AMI and CMI are components of the specific immunity
C. Both involved memory cells (Antibody has it, cell does have it I think)
D. CMI is involved in killing cancer and tumor cells
E. Only AMI is involved in classical pathway for complement fixation -
ANSWER E. Only AMI is involved in classical pathway for complement
fixation
Graft vs host disease occurs when graft cells attack the recipient tissue.
Which of the following statements apply to it?
A. Disease occurs when MHC I on donor tissue does not match with MHC I on
recipient tissue
B. Both are true
C. Disease occurs following bone marrow transplant
D. Neither are true - ANSWER B. Both are true
Immune complex is formed when antigen and antibody bind. Formation of
this complex result in all of the following except:
A) All of these are the consequences of formation of the antigen-antibody
complex
B) Complement fixation via classical pathway
C) Opsonization and marking bacteria for destruction
