Chapter 6: The ABO Blood Group
System
A group O character with warm autoimmune hemolytic anemia may show susceptible reactions
within the ahead grouping due to: - ANS-Red blood cells being lined with antibody
A patient become formerly typed as a blood institution O. Forward grouping was terrible with
anti-A and anti-B. Reverse group confirmed reactivity with A1 cells and B cells. The technologist
suggested this patient's type as A. What technical mistakes befell? - ANS-Clerical errors
A patient who became recently recognized with an obstructed bowel became septic from
Proteus vulgaris. Prior to surgical treatment, a ordinary kind and display become performed.
Thought this man or woman sorts as an A two years ago, his ahead type is constant with an AB
man or woman, albeit weaker in power with anti-B. What is the motive for this discrepancy? -
ANS-Acquired B
A kind-A man or woman demonstrates a 3+ reactivity with A1 cells (reverse grouping). The
ahead grouping with anti-A is 4+. Therefore, the opportunity of a subgroup is excluded. B cells
show a four+ response. The antibody screen is weakly fantastic at 37C, however shows no
reactivity at the AHG phase. An antibody panel is finished and anti-M is recognized. The
affected person phenotypes bad for M antigen. How is the ABO discrepancy resolved? -
ANS-Perform opposite grouping with A1 cells negative for M antigen
A1 lectin agglutinates: - ANS-simplest A1 cells
All of the following are technical mistakes that might result in ABO discrepancies besides: -
ANS-Failure to warm reagents
All of the following are exams performed inside the blood bank to categorise subgroups of A
besides: - ANS-LISS enhancement
All of the following is regular with A3 individuals except? - ANS-4,000 antigenic sites on purple
blood cells
All of the following is authentic regarding formation of the ABH antigens besides? - ANS-A kind
1 shape referes to a beta 1-2 linkage
All of the following may also depress antigen expression besides: - ANS-coronary heary ailment
, All of the following may additionally result in rouleaux formation besides: - ANS-leukemia
All of the following may also bring about vulnerable or lacking antigens besides: -
ANS-hypogammaglobulinemia
All of the subsequent statements are actual regarding ABH soluble substances except: -
ANS-The precursor chain is kind 2 (beta 1-4 linkage)
An AB adult males friends with an AB female. What will be the genotype of the offspring? -
ANS-All of the above
AA, AB, BB
An elderly patient is report as being kind O. The ahead grouping is bad with anti-A and anti-B.
The reverse grouping shows no reactivity with A1 cells and B cells. What can be finished to
accurate the discrepancy? - ANS-Incubate the patient's serum and reagent cells for 15 mins at
room temperature
Anti-A from a collection B character is in general what elegance of immunoglobulin? - ANS-IgM
Antibody titers precise to antigens from the ABO system are usually maximum: - ANS-When the
affected person is around 10 years old
Approximately how many antigen sites can be found on A2 cells? - ANS-260,000
Approximately what number of antigen sites exist on a kind-A1 person's RBC? - ANS-1 million
Cord blood became despatched to the laboratory for blood type determination on twins A and B.
Baby A verified combined-discipline reactions with anti-A and anti-AB and no reactivity with
anti-B. Reverse grouping changed into now not done. Baby B showed a 1+ response with anti-A
and anti-AB. What may be the cause for the variable reactions? - ANS-All of the above
Chimerism
A dimorphic cell population
Dispermy
Forward grouping is defined as - ANS-Detecting antigen(s) on an character's pink blood cells via
reagent antisera
How are ABH antigens shaped? - ANS-Production of specific glycosyltransferases add sugars
to precusor materials
How is polyagglutination resolved? - ANS-Patient cells are examined with a lectin panel
System
A group O character with warm autoimmune hemolytic anemia may show susceptible reactions
within the ahead grouping due to: - ANS-Red blood cells being lined with antibody
A patient become formerly typed as a blood institution O. Forward grouping was terrible with
anti-A and anti-B. Reverse group confirmed reactivity with A1 cells and B cells. The technologist
suggested this patient's type as A. What technical mistakes befell? - ANS-Clerical errors
A patient who became recently recognized with an obstructed bowel became septic from
Proteus vulgaris. Prior to surgical treatment, a ordinary kind and display become performed.
Thought this man or woman sorts as an A two years ago, his ahead type is constant with an AB
man or woman, albeit weaker in power with anti-B. What is the motive for this discrepancy? -
ANS-Acquired B
A kind-A man or woman demonstrates a 3+ reactivity with A1 cells (reverse grouping). The
ahead grouping with anti-A is 4+. Therefore, the opportunity of a subgroup is excluded. B cells
show a four+ response. The antibody screen is weakly fantastic at 37C, however shows no
reactivity at the AHG phase. An antibody panel is finished and anti-M is recognized. The
affected person phenotypes bad for M antigen. How is the ABO discrepancy resolved? -
ANS-Perform opposite grouping with A1 cells negative for M antigen
A1 lectin agglutinates: - ANS-simplest A1 cells
All of the following are technical mistakes that might result in ABO discrepancies besides: -
ANS-Failure to warm reagents
All of the following are exams performed inside the blood bank to categorise subgroups of A
besides: - ANS-LISS enhancement
All of the following is regular with A3 individuals except? - ANS-4,000 antigenic sites on purple
blood cells
All of the following is authentic regarding formation of the ABH antigens besides? - ANS-A kind
1 shape referes to a beta 1-2 linkage
All of the following may also depress antigen expression besides: - ANS-coronary heary ailment
, All of the following may additionally result in rouleaux formation besides: - ANS-leukemia
All of the following may also bring about vulnerable or lacking antigens besides: -
ANS-hypogammaglobulinemia
All of the subsequent statements are actual regarding ABH soluble substances except: -
ANS-The precursor chain is kind 2 (beta 1-4 linkage)
An AB adult males friends with an AB female. What will be the genotype of the offspring? -
ANS-All of the above
AA, AB, BB
An elderly patient is report as being kind O. The ahead grouping is bad with anti-A and anti-B.
The reverse grouping shows no reactivity with A1 cells and B cells. What can be finished to
accurate the discrepancy? - ANS-Incubate the patient's serum and reagent cells for 15 mins at
room temperature
Anti-A from a collection B character is in general what elegance of immunoglobulin? - ANS-IgM
Antibody titers precise to antigens from the ABO system are usually maximum: - ANS-When the
affected person is around 10 years old
Approximately how many antigen sites can be found on A2 cells? - ANS-260,000
Approximately what number of antigen sites exist on a kind-A1 person's RBC? - ANS-1 million
Cord blood became despatched to the laboratory for blood type determination on twins A and B.
Baby A verified combined-discipline reactions with anti-A and anti-AB and no reactivity with
anti-B. Reverse grouping changed into now not done. Baby B showed a 1+ response with anti-A
and anti-AB. What may be the cause for the variable reactions? - ANS-All of the above
Chimerism
A dimorphic cell population
Dispermy
Forward grouping is defined as - ANS-Detecting antigen(s) on an character's pink blood cells via
reagent antisera
How are ABH antigens shaped? - ANS-Production of specific glycosyltransferases add sugars
to precusor materials
How is polyagglutination resolved? - ANS-Patient cells are examined with a lectin panel
