NR 546 Advanced Pharmacology Psychopharmacology
for the Psychiatric-Mental Health Nurse Practitioner
Midterm Exam Week 4
1. How does the orbitofrontal cortex (OFC) affect the amygdala?: inhibits andactivates
the amygdala
2. Wernicke's area is associated with which of the following?: speech compre-hension
3. The limbic system is associated with which of the following: emotion andlearning
4. Which brain structure is most associated with long term memory?: hip-pocampus
5. When prescribing psychotropic medications, the PMHNP knows that these
medications work within which specific areas?: mood
,6. Which of the following are involved in regulating neurotransmission via ex- citation-
secretion coupling?: voltage-sensitive sodium channels and voltage-sen- sitive calcium
channels
7. What system influences the length of time for a drug to achieve efficacy?: -
signal transduction cascades
8. One of the signal transduction cascades, pass the message from a firstreceptor to
a second messenger.: G protein linked systems
9. Human central nervous system communication at synapses is which of thefollowing?:
chemical
10. Which of the following is an excitatory neurotransmitter?: glutamate
11. Which statement correctly pairs the pharmacodynamic effect with its defi-nition?:
,antagonist effect - drug binds to receptor, but does not activate a response
12. A major current hypothesis for the cause of schizophrenia proposes thatN-methyl-
d-aspartate (NMDA) receptors may be which of the following? Correct!: hypofunctional
13. Which medication is least associated with weight gain?: aripiprazole
14. Which dopamine pathway is associated with positive symptoms of schiz-ophrenia?:
mesolimbic pathway
15. Which pathway is associated with negative symptoms?: The mesocorticalpathway
16. Is part of the extrapyramidal nervous system and associated with ex-
trapyramidal symptoms (EPS): nigrostriatal pathway
17. This pathway is associated with hyperprolactinemia.: The tuberoinfundibu-lar
pathway
18. A 34-year old male recently began experiencing breast secretions while receiving
,risperidone . Which dopamine pathway is associated with this sideeffect?:
tuberoinfundibular pathway
19. A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demon-
,strate which of the following most often?: Atypical antipsychotics have equalpositive
symptom antipsychotic actions and low extrapyramidal symptoms.
20. is a syndrome that can be associated with several different psychiatric disorders.
Symptoms include hallucinations, delusions, disorganized speech,disorganized behavior,
and distortions of reality. This syndrome can affect a person's cognition, affective
response, communication, capacity to recognizereality, and ability to relate to others.:
psychosis
21. What Diagnosis require the presence of psychosis?: schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
schizoaffecive disorder
delusional disorder
brief psychotic disorder
psychotic disorder due to a medical condition
22. What diagnosis has a diagnosis of psychosis as a feature?: maniadepression
cognitive disorders
dementia
23. What are some positive symptoms?: Hallucinations
, Delusions
Thought disorder
Hostility
Excitability
24. What are some Negative symptoms?: Affective flatteningAlogia
Anhedonia
Amotivation
Asociality
25. What area of the brain is associated with negative and affective symp-toms?:
Mesocortical and ventromedial prefrontal cortex:
26. What area of the brain is associated with cognitive symptoms?: Dorsolat-eral
27. What area of the brain is associated with aggressive, impulsive symp-toms?:
Orbitofrontal and connections to the amygdala
28. Non-selectively blocks dopamine D2 receptors, specifically in mesolimbicpathway.
Improves Positive Symptoms
Use: Acute & Chronic Schizophrenia & Psychosis: First generation antipsy-chotics
for the Psychiatric-Mental Health Nurse Practitioner
Midterm Exam Week 4
1. How does the orbitofrontal cortex (OFC) affect the amygdala?: inhibits andactivates
the amygdala
2. Wernicke's area is associated with which of the following?: speech compre-hension
3. The limbic system is associated with which of the following: emotion andlearning
4. Which brain structure is most associated with long term memory?: hip-pocampus
5. When prescribing psychotropic medications, the PMHNP knows that these
medications work within which specific areas?: mood
,6. Which of the following are involved in regulating neurotransmission via ex- citation-
secretion coupling?: voltage-sensitive sodium channels and voltage-sen- sitive calcium
channels
7. What system influences the length of time for a drug to achieve efficacy?: -
signal transduction cascades
8. One of the signal transduction cascades, pass the message from a firstreceptor to
a second messenger.: G protein linked systems
9. Human central nervous system communication at synapses is which of thefollowing?:
chemical
10. Which of the following is an excitatory neurotransmitter?: glutamate
11. Which statement correctly pairs the pharmacodynamic effect with its defi-nition?:
,antagonist effect - drug binds to receptor, but does not activate a response
12. A major current hypothesis for the cause of schizophrenia proposes thatN-methyl-
d-aspartate (NMDA) receptors may be which of the following? Correct!: hypofunctional
13. Which medication is least associated with weight gain?: aripiprazole
14. Which dopamine pathway is associated with positive symptoms of schiz-ophrenia?:
mesolimbic pathway
15. Which pathway is associated with negative symptoms?: The mesocorticalpathway
16. Is part of the extrapyramidal nervous system and associated with ex-
trapyramidal symptoms (EPS): nigrostriatal pathway
17. This pathway is associated with hyperprolactinemia.: The tuberoinfundibu-lar
pathway
18. A 34-year old male recently began experiencing breast secretions while receiving
,risperidone . Which dopamine pathway is associated with this sideeffect?:
tuberoinfundibular pathway
19. A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demon-
,strate which of the following most often?: Atypical antipsychotics have equalpositive
symptom antipsychotic actions and low extrapyramidal symptoms.
20. is a syndrome that can be associated with several different psychiatric disorders.
Symptoms include hallucinations, delusions, disorganized speech,disorganized behavior,
and distortions of reality. This syndrome can affect a person's cognition, affective
response, communication, capacity to recognizereality, and ability to relate to others.:
psychosis
21. What Diagnosis require the presence of psychosis?: schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
schizoaffecive disorder
delusional disorder
brief psychotic disorder
psychotic disorder due to a medical condition
22. What diagnosis has a diagnosis of psychosis as a feature?: maniadepression
cognitive disorders
dementia
23. What are some positive symptoms?: Hallucinations
, Delusions
Thought disorder
Hostility
Excitability
24. What are some Negative symptoms?: Affective flatteningAlogia
Anhedonia
Amotivation
Asociality
25. What area of the brain is associated with negative and affective symp-toms?:
Mesocortical and ventromedial prefrontal cortex:
26. What area of the brain is associated with cognitive symptoms?: Dorsolat-eral
27. What area of the brain is associated with aggressive, impulsive symp-toms?:
Orbitofrontal and connections to the amygdala
28. Non-selectively blocks dopamine D2 receptors, specifically in mesolimbicpathway.
Improves Positive Symptoms
Use: Acute & Chronic Schizophrenia & Psychosis: First generation antipsy-chotics
