NR565 / NR565 Advanced Pharmacology
j j j j
NR565 / NR565 Advanced Pharmacology
Fundamentals Midterm / Final Exam|
Questions and 100 % Correct Answers |
Rated A Quiz bank | LATEST, 2023 /
2024 | Chamberlain College
1. Kasey jfractured jhis jankle jin jtwo jplaces jand jis jasking jfor jmedication jfor jhis jpain.
jThe jappropriate jfirst-line jmedication jwould jbe:
- Acetaminophen jwith jhydrocodone j(Vicodin)
2. Jack, jage j8, jhas jattention jdeficit jdisorder j(ADD) jand jis jprescribed
jmethylphenidate j(Ritalin). jHe jand jhis jparents jshould jbe jeducated jabout jthe jside
jeffects jof jmethylphenidate, jwhich jare:
- Insomnia jand jdecreased jappetite
3. Monitoring jfor ja jchild jon jmethylphenidate jfor jattention jdeficit jhyperactivity
jdisorder j(ADHD) jincludes:
- ADHD jsymptoms
- Routine jheight jand jweight jchecks
- Amount jof jmethylphenidate jbeing jused
4. When jprescribing jAdderall j(amphetamine jand jdextroamphetamine) jto jadults jwith
jADHD jthe jnurse jpractitioner jwill jneed jto jmonitor:
- Blood jpressure
5. Common jmistakes jpractitioners jmake jin jtreating janxiety jdisorders jinclude:
- Thinking ja jpartial jresponse jto jmedication jis jacceptable
6. An jappropriate jfirst-line jdrug jto jtry jfor jmild jto jmoderate jgeneralized janxiety
jdisorder jwould jbe:
- Buspirone j(Buspar)
7. An jappropriate jdrug jto jinitially jtreat jpanic jdisorder jis:
- Diazepam j(Valium)
8. Prior jto jstarting jantidepressants, jpatients jshould jhave jlaboratory jtesting jto jrule jout:
- Hypothyroidism
,9. David jis ja j34-year-old jpatient jwho jis jstarting jon jparoxetine j(Paxil) jfor
jdepression. jDavid's jeducation jregarding jhis jmedication jwould jinclude:
- He jmay jexperience jsexual jdysfunction jbeginning ja jmonth jafter jhe jstarts jtherapy.
10. Jamison jhas jbeen jprescribed jcitalopram j(Celexa) jto jtreat jhis jdepression. jEducation
jregarding jhow jquickly jselective jserotonin jreuptake jinhibitor j(SSRI) jantidepressants
jwork jwould jbe:
- Appetite jand jconcentration jimprove jin jthe jfirst j1 jto j2 jweeks.
11. The jracial jdifference jin jdrug jpharmacokinetics jseen jin jAmerican jIndian jor
jAlaskan jNatives jare:
- Largely junknown jdue jto jlack jof jstudies jof jthis jpopulation
12. Pharmacokinetics jamong jAsians jare juniversal jto jall jthe jAsian jethnic jgroups.
A. True
B. False
13. Alterations jin jdrug jmetabolism jamong jAsians jmay jlead jto:
- Slower jmetabolism jof jantidepressants, jrequiring jlower jdoses
14. Asians jfrom jEastern jAsia jare jknown jto jbe jfast jacetylators. jFast jacetylators:
- Require jhigher jdoses jof jdrugs jmetabolized jby jacetylization jto jachieve jefficacy
15. Hispanic jnative jhealers j(curanderas):
A. Are jnot jheavily jutilized jby jHispanics jwho jimmigrate jto jthe jUnited jStates
B. Use jherbs jand jteas jin jtheir jtreatment jof jillness
C. Provide junsafe jadvice jto jHispanics jand jshould jnot jbe jtrusted
D. Need jto jbe jlicensed jin jtheir jhome jcountry jin jorder jto jpractice jin jthe jUnited jStates j
16. Genetic jpolymorphisms jaccount jfor jdifferences jin jmetabolism, jincluding:
- Poor jmetabolizers, jwho jlack ja jworking jenzyme
- Intermediate jmetabolizers, jwho jhave jone jworking, jwild-type jallele jand jone
jmutant jallele
- Extensive jmetabolizers, jwith jtwo jnormally jfunctioning jalleles
17. Up jto j21% jof jAsians jare jultra-rapid j2D6 jmetabolizers, jleading jto:
- Increased jdosages jneeded jof jdrugs jmetabolized jby j2D6, jsuch jas jthe
jselective jserotonin jreuptake jinhibitors
18. Drugs jthat juse jCYP j3A4 jisoenzymes jfor jmetabolism jmay:
- Induce jthe jmetabolism jof janother jdrug
, - Inhibit jthe jmetabolism jof janother jdrug
19. Rifampin jis ja jnonspecific jCYP450 jinducer jthat jmay:
- Induce jthe jmetabolism jof jdrugs, jsuch jas joral jcontraceptives, jleading jto
jtherapeutic jfailure
20. Inhibition jof jP-glycoprotein jby ja jdrug jsuch jas jquinidine jmay jlead jto:
- Increased jlevels jof ja jco-administered jdrug, jsuch jas jdigoxin, jthat jrequires
jP- jglycoprotein jfor jabsorption jand jelimination
21. Warfarin jresistance jmay jbe jseen jin jpatients jwith jVCORC1 jmutation, jleading jto:
- Decreased jresponse jto jwarfarin
22. Genetic jtesting jfor jVCORC1 jmutation jto jassess jpotential jwarfarin jresistance jis
jrequired jprior jto jprescribing jwarfarin.
A. True
B. False
23. Pharmacogenetic jtesting jis jrequired jby jthe jU.S. jFood jand jDrug jAdministration jprior
jto jprescribing:
- Cetuximab
24. Carbamazepine jhas ja jBlack jBox jWarning jrecommending jtesting jfor jthe jHLA-
B*1502 jallele jin jpatients jwith jAsian jancestry jprior jto jstarting jtherapy jdue jto:
- Increased jrisk jfor jStevens-Johnson jsyndrome jin jAsian jpatients jwith jHLA-
B*1502 jallele
25. A jgenetic jvariation jin jhow jthe jmetabolite jof jthe jcancer jdrug jirinotecan jSN-38
jis jinactivated jby jthe jbody jmay jlead jto
- Increased jadverse jdrug jreactions, jsuch jas jneutropenia
26. Patients jwho jhave ja jpoor jmetabolism jphenotype jwill jhave:
- Slowed jmetabolism jof ja jprodrug jinto jan jactive jdrug, jleading jto jaccumulation
jof jprodrug
27. A jpatient's jnutritional jintake jand jlaboratory jresults jreflect jhypoalbuminemia. jThis
jis jcritical jto jprescribing jbecause:
- Distribution jof jdrugs jto jtarget jtissue jmay jbe jaffected.
28. Drugs jthat jhave ja jsignificant jfirst-pass jeffect:
- Are jrapidly jmetabolized jby jthe jliver jand jmay jhave jlittle jif jany jdesired jaction
29. The jroute jof jexcretion jof ja jvolatile jdrug jwill jlikely jbe jthe:
- Lungs
j j j j
NR565 / NR565 Advanced Pharmacology
Fundamentals Midterm / Final Exam|
Questions and 100 % Correct Answers |
Rated A Quiz bank | LATEST, 2023 /
2024 | Chamberlain College
1. Kasey jfractured jhis jankle jin jtwo jplaces jand jis jasking jfor jmedication jfor jhis jpain.
jThe jappropriate jfirst-line jmedication jwould jbe:
- Acetaminophen jwith jhydrocodone j(Vicodin)
2. Jack, jage j8, jhas jattention jdeficit jdisorder j(ADD) jand jis jprescribed
jmethylphenidate j(Ritalin). jHe jand jhis jparents jshould jbe jeducated jabout jthe jside
jeffects jof jmethylphenidate, jwhich jare:
- Insomnia jand jdecreased jappetite
3. Monitoring jfor ja jchild jon jmethylphenidate jfor jattention jdeficit jhyperactivity
jdisorder j(ADHD) jincludes:
- ADHD jsymptoms
- Routine jheight jand jweight jchecks
- Amount jof jmethylphenidate jbeing jused
4. When jprescribing jAdderall j(amphetamine jand jdextroamphetamine) jto jadults jwith
jADHD jthe jnurse jpractitioner jwill jneed jto jmonitor:
- Blood jpressure
5. Common jmistakes jpractitioners jmake jin jtreating janxiety jdisorders jinclude:
- Thinking ja jpartial jresponse jto jmedication jis jacceptable
6. An jappropriate jfirst-line jdrug jto jtry jfor jmild jto jmoderate jgeneralized janxiety
jdisorder jwould jbe:
- Buspirone j(Buspar)
7. An jappropriate jdrug jto jinitially jtreat jpanic jdisorder jis:
- Diazepam j(Valium)
8. Prior jto jstarting jantidepressants, jpatients jshould jhave jlaboratory jtesting jto jrule jout:
- Hypothyroidism
,9. David jis ja j34-year-old jpatient jwho jis jstarting jon jparoxetine j(Paxil) jfor
jdepression. jDavid's jeducation jregarding jhis jmedication jwould jinclude:
- He jmay jexperience jsexual jdysfunction jbeginning ja jmonth jafter jhe jstarts jtherapy.
10. Jamison jhas jbeen jprescribed jcitalopram j(Celexa) jto jtreat jhis jdepression. jEducation
jregarding jhow jquickly jselective jserotonin jreuptake jinhibitor j(SSRI) jantidepressants
jwork jwould jbe:
- Appetite jand jconcentration jimprove jin jthe jfirst j1 jto j2 jweeks.
11. The jracial jdifference jin jdrug jpharmacokinetics jseen jin jAmerican jIndian jor
jAlaskan jNatives jare:
- Largely junknown jdue jto jlack jof jstudies jof jthis jpopulation
12. Pharmacokinetics jamong jAsians jare juniversal jto jall jthe jAsian jethnic jgroups.
A. True
B. False
13. Alterations jin jdrug jmetabolism jamong jAsians jmay jlead jto:
- Slower jmetabolism jof jantidepressants, jrequiring jlower jdoses
14. Asians jfrom jEastern jAsia jare jknown jto jbe jfast jacetylators. jFast jacetylators:
- Require jhigher jdoses jof jdrugs jmetabolized jby jacetylization jto jachieve jefficacy
15. Hispanic jnative jhealers j(curanderas):
A. Are jnot jheavily jutilized jby jHispanics jwho jimmigrate jto jthe jUnited jStates
B. Use jherbs jand jteas jin jtheir jtreatment jof jillness
C. Provide junsafe jadvice jto jHispanics jand jshould jnot jbe jtrusted
D. Need jto jbe jlicensed jin jtheir jhome jcountry jin jorder jto jpractice jin jthe jUnited jStates j
16. Genetic jpolymorphisms jaccount jfor jdifferences jin jmetabolism, jincluding:
- Poor jmetabolizers, jwho jlack ja jworking jenzyme
- Intermediate jmetabolizers, jwho jhave jone jworking, jwild-type jallele jand jone
jmutant jallele
- Extensive jmetabolizers, jwith jtwo jnormally jfunctioning jalleles
17. Up jto j21% jof jAsians jare jultra-rapid j2D6 jmetabolizers, jleading jto:
- Increased jdosages jneeded jof jdrugs jmetabolized jby j2D6, jsuch jas jthe
jselective jserotonin jreuptake jinhibitors
18. Drugs jthat juse jCYP j3A4 jisoenzymes jfor jmetabolism jmay:
- Induce jthe jmetabolism jof janother jdrug
, - Inhibit jthe jmetabolism jof janother jdrug
19. Rifampin jis ja jnonspecific jCYP450 jinducer jthat jmay:
- Induce jthe jmetabolism jof jdrugs, jsuch jas joral jcontraceptives, jleading jto
jtherapeutic jfailure
20. Inhibition jof jP-glycoprotein jby ja jdrug jsuch jas jquinidine jmay jlead jto:
- Increased jlevels jof ja jco-administered jdrug, jsuch jas jdigoxin, jthat jrequires
jP- jglycoprotein jfor jabsorption jand jelimination
21. Warfarin jresistance jmay jbe jseen jin jpatients jwith jVCORC1 jmutation, jleading jto:
- Decreased jresponse jto jwarfarin
22. Genetic jtesting jfor jVCORC1 jmutation jto jassess jpotential jwarfarin jresistance jis
jrequired jprior jto jprescribing jwarfarin.
A. True
B. False
23. Pharmacogenetic jtesting jis jrequired jby jthe jU.S. jFood jand jDrug jAdministration jprior
jto jprescribing:
- Cetuximab
24. Carbamazepine jhas ja jBlack jBox jWarning jrecommending jtesting jfor jthe jHLA-
B*1502 jallele jin jpatients jwith jAsian jancestry jprior jto jstarting jtherapy jdue jto:
- Increased jrisk jfor jStevens-Johnson jsyndrome jin jAsian jpatients jwith jHLA-
B*1502 jallele
25. A jgenetic jvariation jin jhow jthe jmetabolite jof jthe jcancer jdrug jirinotecan jSN-38
jis jinactivated jby jthe jbody jmay jlead jto
- Increased jadverse jdrug jreactions, jsuch jas jneutropenia
26. Patients jwho jhave ja jpoor jmetabolism jphenotype jwill jhave:
- Slowed jmetabolism jof ja jprodrug jinto jan jactive jdrug, jleading jto jaccumulation
jof jprodrug
27. A jpatient's jnutritional jintake jand jlaboratory jresults jreflect jhypoalbuminemia. jThis
jis jcritical jto jprescribing jbecause:
- Distribution jof jdrugs jto jtarget jtissue jmay jbe jaffected.
28. Drugs jthat jhave ja jsignificant jfirst-pass jeffect:
- Are jrapidly jmetabolized jby jthe jliver jand jmay jhave jlittle jif jany jdesired jaction
29. The jroute jof jexcretion jof ja jvolatile jdrug jwill jlikely jbe jthe:
- Lungs
