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NWHSU Histology Exam 1 Review
Questions and Answers (100% Pass)
Chromatin function:
✓ Synthesis of rRNA
Chromatin is made up of what?
✓ Double Stranded DNA and nucleoproteins(Histones)
Euchromatin
✓ -Vesicular and leptochromatic
✓ -transcriptionally active and electron-lucent
Heterochromatin
✓ -Condensed and pachychromtic
✓ -Transcriptionally inactive and when stained has basophilic clumps
Nuclear envelope consists of:
✓ -2 parallel membranes (outer and inner nuclear membrane)
✓ -Outer is continuous with rER
Master01 | October, 2024/2025 | Latest update
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The thin space between the two nuclear envelope membranes:
✓ Perinuclear cisterna
Openings on nuclear envelope
✓ nuclear pores
The inner nuclear membrane on the nuclear envelope is supported by:
✓ Nuclear Lamina
During mitosis what causes the disassembly of nuclear envelope?
✓ Phosphorylation of the lamin
Steps of creating chromosomes
✓ -Double helix DNA wound around 8 histone proteins assemble into
nucleosomes(structural unit of chromatin packaging)
✓ -these chromatins are fibrils which fold together with each other to
make fibers. (tight fold is heterochromatin, loose fold is euchromatin)
✓ -fibers will further condense to form chromosomes
Karyotype contains
Master01 | October, 2024/2025 | Latest update
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✓ 22 pairs of autosomes and 1 pair of sex chromosomes (XX or XY)
All somatic cells have:
✓ 46 chromosomes (diploid 2n)
All germs cells(after meiosis) have
✓ 23 chromosomes (haploid 1n
What is used in karyotype analysis to stop diving cells?
✓ Colchicine
What stage are the cells stopped at in karyotype analysis?
✓ Metaphase( because the chromosomes are maximally condensed)
Metaphase chromosomes appear as:
✓ sister chromatids
Trisomy of the 21st chromosome is called
✓ Down Syndrome
Master01 | October, 2024/2025 | Latest update
NWHSU Histology Exam 1 Review
Questions and Answers (100% Pass)
Chromatin function:
✓ Synthesis of rRNA
Chromatin is made up of what?
✓ Double Stranded DNA and nucleoproteins(Histones)
Euchromatin
✓ -Vesicular and leptochromatic
✓ -transcriptionally active and electron-lucent
Heterochromatin
✓ -Condensed and pachychromtic
✓ -Transcriptionally inactive and when stained has basophilic clumps
Nuclear envelope consists of:
✓ -2 parallel membranes (outer and inner nuclear membrane)
✓ -Outer is continuous with rER
Master01 | October, 2024/2025 | Latest update
, 1|Page | © copyright 2024/2025 | Grade A+
The thin space between the two nuclear envelope membranes:
✓ Perinuclear cisterna
Openings on nuclear envelope
✓ nuclear pores
The inner nuclear membrane on the nuclear envelope is supported by:
✓ Nuclear Lamina
During mitosis what causes the disassembly of nuclear envelope?
✓ Phosphorylation of the lamin
Steps of creating chromosomes
✓ -Double helix DNA wound around 8 histone proteins assemble into
nucleosomes(structural unit of chromatin packaging)
✓ -these chromatins are fibrils which fold together with each other to
make fibers. (tight fold is heterochromatin, loose fold is euchromatin)
✓ -fibers will further condense to form chromosomes
Karyotype contains
Master01 | October, 2024/2025 | Latest update
, 1|Page | © copyright 2024/2025 | Grade A+
✓ 22 pairs of autosomes and 1 pair of sex chromosomes (XX or XY)
All somatic cells have:
✓ 46 chromosomes (diploid 2n)
All germs cells(after meiosis) have
✓ 23 chromosomes (haploid 1n
What is used in karyotype analysis to stop diving cells?
✓ Colchicine
What stage are the cells stopped at in karyotype analysis?
✓ Metaphase( because the chromosomes are maximally condensed)
Metaphase chromosomes appear as:
✓ sister chromatids
Trisomy of the 21st chromosome is called
✓ Down Syndrome
Master01 | October, 2024/2025 | Latest update
