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MLS HEMATOLOGY EXAM /HEMATOLOGY MLS ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A+

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MLS HEMATOLOGY EXAM /HEMATOLOGY MLS ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A+

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MLS HEMATOLOGY EXAM /HEMATOLOGY MLS ACTUAL
EXAM 400 QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |
ALREADY GRADED A+
volume of blood in adult - ANSWER: 4-6 L

pH of blood - ANSWER: 7.35-7.45

make up of whole blood - ANSWER: 55% plasma
45% erythrocytes
<1 % buffy coat

contains fibrinogen - ANSWER: plasma

RBC production 1-2 months fetal - ANSWER: yolk sac

RBC production 3-7 months fetal - ANSWER: liver and spleen

RBC production adults - ANSWER: bone marrow

At what stage of mitosis does the RBC leave the bone marrow? - ANSWER: G0: non
dividing

CFU-GEMM - ANSWER: colony forming unit (CFU) for myeloid cells

Do lymphatic stem cells self replicate? - ANSWER: no

rHuG-CSF - ANSWER: granulocyte stimulating factor, for AIDS patients

rHuEPO - ANSWER: increases RBC production, treatment of anemia

Erythropoietin - ANSWER: A hormone produced and released by the kidney that
stimulates the production of RBCs by the bone marrow.

Does RNA production in maturing RBCs increase or decrease? - ANSWER: decrease

Pronormoblast - ANSWER: Rubriblast

Basophilic normoblast - ANSWER: Prorubricyte

Polychromatophilic normoblast - ANSWER: Rubricyte

Orthochromic normoblast - ANSWER: Metarubricyte

, Polychromatophilic erythrocyte - ANSWER: reticulocyte

Polychromatophilic normoblast - ANSWER: clumping of nucleus

Necessary things for a RBC - ANSWER: normal membrane
Hgb
RBC metabolic pathways

Glycophorin - ANSWER: gives net - charge (zeta potential) to RBCs so they repel one
another

Spectrin - ANSWER: rod-like molecule to maintain integrity of RBC

What are RBCs easily permeable to? - ANSWER: H20, Cl-, HCO3-

What lipids are found on membrane of RBC? - ANSWER: cholesterol, choline
phospholipids, glycolipids, amino phospholipids

Form of iron used by heme - ANSWER: Ferrous

builds up with Pb poisoning - ANSWER: Delta-aminolevulinate

builds up with Pb poisoning - ANSWER: Coproporphyrinogen III

Transferin - ANSWER: transports Fe+3 to membrane of RBC precursors, inserts Fe+2
into protoporphyrin ring in mitochondria

Chromosome 16 - ANSWER: zeta, alpha

Chromosome 11 - ANSWER: epsilon, gamma, beta

Hgb Gower 1 - ANSWER: 2 zeta, 2 epsilon

Hgb Gower 2 - ANSWER: 2 alpha, 2 epsilon

Hgb Portland - ANSWER: 2 zeta, 2 gamma

Hgb A - ANSWER: 2 alpha, 2 beta

Hgb A1C - ANSWER: glycosylated hgb A

Hgb A2 - ANSWER: 2 alpha, 2 delta

Hgb F - ANSWER: 2 alpha, 2 gamma

alpha chains - ANSWER: 141 amino acids

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