UNE Medical Biochemistry Exam 1 Weeks 1-8 Actual Questions and Answers with Verified solutions | Latest Update 2025

UNE Medical Biochemistry Exam 1 Weeks 1-8 Actual Questions and Answers with Verified solutions | Latest Update 2025 W4 Which of the following hormones is best described as anabolic? A) Epinephrine B) Insulin C) Cortisol D) Glucagon - ANSWER Insulin Insulin is an anabolic hormone while all others listed are predominantly catabolic. T1 A 22-year old female presents to the emergency department with acute abdominal pain. She indicates the pain came on rapidly in her mid-abdominal region. She has vomited several times over the last 4 hours. A diagnosis of acute pancreatitis is made and she is rushed to surgery. Elevation of which of the following serum enzymes would be consistent with this diagnosis? A) Lactate dehydrogenase B) Amylase C) Troponin D) Creatine Kinase - ANSWER Amylase T1 Which of the following best describes a protein domain? A) Regions of a protein that have no specific function B) A small grouping of secondary structures C) A linker region between 2 α-helical structures D) A section of a protein structure sufficient to form a particular chemical or physical task - ANSWER A section of a protein structure sufficient to form a particular chemical or physical task T1, Q1 An enzyme has a mutation within the substrate binding site that reduces the binding of the coenzyme needed for covalent catalysis. Which of the following is likely to result as a consequence of this mutation? A) The enzyme will function normally B) The enzyme will use an alternative coenzyme for the reaction C) The enzyme will no be able to form the transition state complex D) The enzyme will not be able to bind substrate - ANSWER The enzyme will not be able to form the transition state complex *Loss of coenzyme binding will result in inability to form the transition substrate enzyme complex* T1 A 55-year old man is brought to the emergency room with a chief complaint of chest pain and tingling in his left arm. Elevation of which of the following enzymes in circulation would be most indicative of a myocardial infarction? A) Amylase B) Troponin C) Lipase D) Lactate Dehydrogenase - ANSWER Troponin T1 Cleavage of fructose 1,6-biphosphate to dihydroxyacetone and glyceraldehyde 3-phosphate involves the breaking of a carbon-carbon bond through a process other than oxidation or hydrolysis. This is achieved by what class of enzymes? A) Lyase B) Transferase C) Hydrolase D) Ligase - ANSWER Lyase *Review the 6 classes of enzymes. Lyases cleave bonds between C-C, C-O, and C-N to generate double bonds* T1, Q1 Which of the following best describes the structure of heme? A) An N-linked glycolysation B) A nicotinamide structure that is readily oxidized C) A negatively charged phosphate group D) A planar polyphyrin ring that binds iron - ANSWER A planar polyphyrin ring that binds iron T1 Which of the following best describes tertiary structure? A) Interactions between single amino acids adjacent to one another B) Interactions between α-helices and β sheets to form a domain C) Interactions between amino acids 4 residues away from one another D) Interactions between differing subunits of a protein - ANSWER Interactions between α-helices and β sheets to form a domain *Tertiary structure is best described as the entire three-dimensional conformation of a polypeptide including how secondary structural features- helices, sheets, bend, turns and loops - assemble to form domains and how these domains..............................................................