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Grade.
1) Scientists have found that extracellular matrix components may induce specific gene
expression in embryonic tissues such as the liver and testes. For this to happen, there
must be direct communication between the extracellular matrix and the developing cells.
Which kind of transmembrane protein would most likely be involved in this kind of
induction? - CORRECT ANSWERS -A) integrins
2) One of the major categories of receptors in the plasma membrane functions by
forming dimers, adding phosphate groups, and then activating relay proteins. Which
type does this? - CORRECT ANSWERS -D) receptor tyrosine kinases
3) Which of the following statements describes a likely effect of a drug designed that
inhibits the cellular response to testosterone? - CORRECT ANSWERS -B) The
transcription of certain genes would decrease.
4) Many G protein-coupled receptors contain seven transmembrane α-helical domains.
The amino end of the protein lies at the exterior of the plasma membrane. Loops of
amino acids connect the helices either at the exterior surface or on the cytosolic surface
of the membrane. The loop on the cytosolic side between helices 5 and 6 is usually
substantially longer than the others. Where would you expect to find the carboxyl end of
the protein? - CORRECT ANSWERS -B) at the cytosolic surface
5) Many G protein-coupled receptors contain seven transmembrane α-helical domains.
The amino end of the protein lies at the exterior of the plasma membrane. Loops of
amino acids connect the helices either at the exterior surface or on the cytosolic surface
of the membrane. The loop on the cytosolic side between helices 5 and 6 is usually
substantially longer than the others. Where would a coupled G protein most likely
interact with this receptor? - CORRECT ANSWERS -D) at the loop between H5 and H6
6) Binding of a signaling molecule to which type of receptor leads directly to a change in
the distribution of ions on opposite sides of the membrane? - CORRECT ANSWERS -
C) ligand-gated ion channel
7) Why does testosterone, a lipid-soluble signaling molecule that crosses the
membranes of all cells, affect only target cells? - CORRECT ANSWERS -B) Intracellular
receptors for testosterone are present only in target cells.
, 8) If an animal cell suddenly lost the ability to produce GTP, what might happen to its
signaling system? - CORRECT ANSWERS -A) It would not be able to activate G
proteins on the cytoplasmic side of the plasma membrane.
9) In yeast signal transduction, a yeast cell releases a mating factor, which ________. -
CORRECT ANSWERS -C) binds to receptors on the membranes of other types of yeast
cells
10) Yeast cells of mating type a are genetically engineered to produce only mating
factor α instead of the normal mating factor a. The gene for the mating factor receptor
was unaltered. How will these engineered cells behave in terms of mating? - CORRECT
ANSWERS -C) They will mate with each other or with normal mating type a cells, but
not with normal mating type α cells.
11) In the formation of biofilms, such as those forming on unbrushed teeth, cell signaling
serves which function? - CORRECT ANSWERS -B) aggregation of bacteria that can
cause cavities
12) Which of the following is a type of local signaling in which a cell secretes a signal
molecule that affects neighboring cells? - CORRECT ANSWERS -C) paracrine
signaling
13) Hormones are chemical substances produced in one organ that are released into
the bloodstream and affect the function of a target organ. Which of the following
conditions is required for the target organ to respond to a particular hormone? -
CORRECT ANSWERS -D) The target organ must have receptors that recognize and
bind the hormone molecule.
14) In which of the following ways do plant hormones differ from hormones in animals? -
CORRECT ANSWERS -A) Plant hormones frequently travel through the air as a gas.
15) When a neuron responds to a particular neurotransmitter by opening gated ion
channels, the neurotransmitter is serving as which part of the signal pathway? -
CORRECT ANSWERS -C) signal molecule
16) Use the following figure to answer the question. Which of the following types of
signaling is represented in the figure? - CORRECT ANSWERS -D) synaptic
17) Use the following figure to answer the question. In the figure, the dots in the space
between the two structures represent which of the following? - CORRECT ANSWERS -
C) neurotransmitters
18) Which observation suggested to Sutherland the involvement of a second
messenger in epinephrine's effect on liver cells? - CORRECT ANSWERS -B) Glycogen
breakdown was observed only when epinephrine was administered to intact cells.