PTCB EXAM TEST BANK Questions & Answers
1. A pharmacy technician received a prescription with the following sig: "1supp PRN
nausea / vomiting". What is the route of administration?
By mouth
By rectum
By ear
Transdermal:
ANSWER By rectum
Reason: The "supp" abbreviation stands for suppository. Suppository is a solidpreparation that is
intended to be inserted in the rectum or vagina.
2. Which of the following vitamins would reduce the effectiveness of warfarin?
Vitamin A
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Vitamin C
Vitamin D
Vitamin K:
ANSWER Vitamin K
Reason: Warfarin is a blood thinner, which works by competitively inhibiting VitaminK epoxide
reductase complex 1 (VKORC-1). Vitamin K, on the other hand, helps with blood clotting.
Vitamin K reduces the effect of warfarin by causing blood to clotfaster.
A patient's prescription of warfarin is therefore adjusted to how much Vitamin K theyconsume in
a day - so it is important that they consume the same amount of Vitamin K each day (through
supplements and foods containing Vitamin K, especially green leafy vegetables) in order for
warfarin to be therapeutic.
3. Naloxone is an antidote for opioid overdose.The mechanism of action ofnaloxone to
the opioid is an example of .
Addiction
Antagonism
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Synergism
Potentiation:
ANSWER Antagonism
Reason: Antagonism is defined as the action of one drug counteracting the actionof the other
drug.
4. What is the beyond-use-date of a Novolog vial after it is opened and punc-tured?
24 hours
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7 days
14 days
28 days:
ANSWER 28 days
Reason: A Novolog vial is a multi-dose vial.After the initial puncture, Novolog is goodat room
temperature for 28 days.
5. St. John's Wort is contraindicated with which of the following medications?
Carvedilol
Hydrocodone
Fluoxetine
Lisinopril:
ANSWER Fluoxetine
Reason: Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). BothSt. John's
Wort and SSRIs are used for the treatment of depression by increasing the level of serotonin.
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