ONS ONCC CHEMOTHERAPY
IMMUNOTHERAPY CERTIFICATE EXAM
LATEST 2023-2024 QUESTIONS AND ANSWERS
(VERIFIED ANSWERS)
3 major phases of cell division: - CORRECT ANSWER
>>Interphase
Mitotic phase
Cytokinesis
3 steps of interphase: - CORRECT ANSWER >>First growth
phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
4 phases of mitosis: - CORRECT ANSWER >>Prophase
Metaphase
Anaphase
Telophase
Innate immunity: - CORRECT ANSWER >>Non-specific
response, either:
1. Barrier (skin, mucous membranes, flora of skin/gut)
,2. Cellular components (phagocytes, natural killer cells,
granulocytes, macrophages)
Adaptive immunity: - CORRECT ANSWER >>Follows innate
immunity if unsuccessful. Memory immunity, including:
1. Humoral immunity (production of antibodies or
immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reactions and limit
inflammatory responses)
Define mutations - CORRECT ANSWER >>Variations in the
nucleotide sequence of a gene
3 main goals of treatment: - CORRECT ANSWER >>Cure
Control
Palliation
Define neoadjuvant therapy - CORRECT ANSWER >>Treatment
is given prior to surgery to shrink the tumor
,Define adjuvant therapy - CORRECT ANSWER >>Additional
cancer treatment given after the primary treatment to lower the
risk that the cancer reoccur
Define conditioning/preparative therapy - CORRECT ANSWER
>>Treatments used to prepare a patient for stem cell
transplantation
2 types of conditioning therapies: - CORRECT ANSWER
>>Myeloablative
Nonmyeloablative
Define dose density - CORRECT ANSWER >>Drug dose per unit
of time
Define dose intensity - CORRECT ANSWER >>Amount of drug
delivered over time
How is relative dose intensity (RDI) calculated? - CORRECT
ANSWER >>By comparing the dose that the patient ACTUALLY
received to the planned dose of the standard regimen
, How do alkylating agents work? - CORRECT ANSWER >>By
causing a break in the DNA helix strand, interfering with DNA
replication and causing cell death
3 subcategories of alkylating agents: - CORRECT ANSWER >>1.
Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still
termed alkylating agents as they work similarly)
3. Nitrosoureas
Most common subcategory of alkylating agents: - CORRECT
ANSWER >>Nitrogen mustards
Common alkylating agents: - CORRECT ANSWER
>>Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - CORRECT ANSWER
>>Cisplatin (Platinol)
Carboplatin (Paraplatin)
IMMUNOTHERAPY CERTIFICATE EXAM
LATEST 2023-2024 QUESTIONS AND ANSWERS
(VERIFIED ANSWERS)
3 major phases of cell division: - CORRECT ANSWER
>>Interphase
Mitotic phase
Cytokinesis
3 steps of interphase: - CORRECT ANSWER >>First growth
phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
4 phases of mitosis: - CORRECT ANSWER >>Prophase
Metaphase
Anaphase
Telophase
Innate immunity: - CORRECT ANSWER >>Non-specific
response, either:
1. Barrier (skin, mucous membranes, flora of skin/gut)
,2. Cellular components (phagocytes, natural killer cells,
granulocytes, macrophages)
Adaptive immunity: - CORRECT ANSWER >>Follows innate
immunity if unsuccessful. Memory immunity, including:
1. Humoral immunity (production of antibodies or
immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reactions and limit
inflammatory responses)
Define mutations - CORRECT ANSWER >>Variations in the
nucleotide sequence of a gene
3 main goals of treatment: - CORRECT ANSWER >>Cure
Control
Palliation
Define neoadjuvant therapy - CORRECT ANSWER >>Treatment
is given prior to surgery to shrink the tumor
,Define adjuvant therapy - CORRECT ANSWER >>Additional
cancer treatment given after the primary treatment to lower the
risk that the cancer reoccur
Define conditioning/preparative therapy - CORRECT ANSWER
>>Treatments used to prepare a patient for stem cell
transplantation
2 types of conditioning therapies: - CORRECT ANSWER
>>Myeloablative
Nonmyeloablative
Define dose density - CORRECT ANSWER >>Drug dose per unit
of time
Define dose intensity - CORRECT ANSWER >>Amount of drug
delivered over time
How is relative dose intensity (RDI) calculated? - CORRECT
ANSWER >>By comparing the dose that the patient ACTUALLY
received to the planned dose of the standard regimen
, How do alkylating agents work? - CORRECT ANSWER >>By
causing a break in the DNA helix strand, interfering with DNA
replication and causing cell death
3 subcategories of alkylating agents: - CORRECT ANSWER >>1.
Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still
termed alkylating agents as they work similarly)
3. Nitrosoureas
Most common subcategory of alkylating agents: - CORRECT
ANSWER >>Nitrogen mustards
Common alkylating agents: - CORRECT ANSWER
>>Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - CORRECT ANSWER
>>Cisplatin (Platinol)
Carboplatin (Paraplatin)
