ASCP HEMATOLOGY EXAM REVIEW 2024/ACTUAL 250 EXAM QUESTIONS WITH CORRECT DETAILED AND VERIFIED ANSWERS/100% CORRECT/LATEST UPDATE

ASCP HEMATOLOGY EXAM REVIEW 2024/ACTUAL
250 EXAM QUESTIONS WITH CORRECT DETAILED
AND VERIFIED ANSWERS/100% CORRECT/LATEST
UPDATE 2024-2025



Name the locations of active marrow in adults: - RIGHT ANS:->>>sternum, skull,

ribs, pelvis, vertebrae



Where does hematopoiesis take place during the first 2 months of gestation? -

RIGHT ANS:->>>yolk sac



Where does the majority of hematopoiesis take place during the 2nd through 7th

month of gestation? - RIGHT ANS:->>>spleen



When does the bone marrow take over hematopoiesis? - RIGHT ANS:->>>after

birth



What are the stages in order of the erythrocyte lineage? - RIGHT ANS:-

>>>(1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte,

(6)erytrocyte



What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil)

,lineage? - RIGHT ANS:->>>(1)myeloblast, (2)promyelocyte, (3)myelocyte,

(4)metamyelocyte, (5)band, (6)segmented (7)eos/baso



What are the stages in order of the macrophage lineage? - RIGHT ANS:-

>>>(1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage



What are the stages in order of the platelet lineage? - RIGHT ANS:-

>>>(1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet



What are the stages in order of the lymphocyte lineage? - RIGHT ANS:-

>>>(1)lymphoblast, (2)prolymphocyte, (3)lymphocyte



Which growth factors stimulate the erythrocyte lineage? - RIGHT ANS:->>>GM-

CSF, EPO, IL-3



Which growth factors stimulate the granulocyte lineages? - RIGHT ANS:->>>GM-

CSF, IL- 3



Which growth factors stimulate the platelet lineage? - RIGHT ANS:->>>GM-CSF,

IL-3, TPO



Which growth factors stimulate the lymphocyte lineage? - RIGHT ANS:->>>IL-2,

,IL-4, IL-6, IL-7

Which protein functions in the transport of Fe? - RIGHT ANS:->>>transferrin



What is the major storage form of Fe? - RIGHT ANS:->>>ferritin



What is the long-term (H20) insoluble Fe storage form called? - RIGHT ANS:-

>>>hemosiderin

Excess Iron is stored where? What does this cause? - RIGHT ANS:->>>tissues and

body organs, hemosiderosis, hemochromatosis



Porphyrias are attributed to? - RIGHT ANS:->>>excessive formation of porphrins

due to blockages in any enzymatic step in the heme synthesis pathway.



Red or port wine colored urine can be seen in which condition related to the build up

of heme precursors? - RIGHT ANS:->>>porphyria



Neuropsychiatirc symptoms are seen when a build up of which precursors occurs? -

RIGHT ANS:->>>early precursors (Delta-aminolevulinic acid/Porphobilinogen)



Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a build

up of which precursors occurs? - RIGHT ANS:->>>later precursors

(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)

, Synthesis of heme requires what two components? - RIGHT ANS:->>>iron,

protoporphyrin



What are the heme precursors in order of synthesis? - RIGHT ANS:->>>(1)delta-

aminolevulinic acid, (2)porphobilinogen, (3)uroporphyrinogen,

(4)coproporphyrinogen, (5)protoporphyrin, (6)heme



What type of hemoglobin is seen primarily in newborns? - RIGHT ANS:->>>Hgb F



What type of hemoglobin is seen primarily in adults? - RIGHT ANS:->>>Hgb A2



What type of hemoglobin is rarely seen in adults as well as newborns? - RIGHT

ANS:->>>Hgb A



What hemoglobin types are seen in embryos but not in adults or newborns? - RIGHT

ANS:->>>gower I, gower II, portland



All non-embryonic hemoglobin types are comprised of what type of globin chain? -

RIGHT ANS:->>>alpha



Hemoglobin A2 is composed of what types of globin chains? - RIGHT ANS:-