Immunology Lab 11 - Aim CRP Test
What does CRP stand for? correct answers C-reactive protein
CRP consists of how many identical subunits? //
What type of bonds hold it together? correct answers 5 identical subunits held together
by non-covalent bonds
Where is CRP synthesized? correct answers liver
CRP has actions similar to that of an antibody, what are its actions? correct answers
trace constituent of serum; originally thought to be an antibody to the c-polysaccharide
of pneumococci
- actions: opsonization, agglutination, precipitation, activation of complement by
classical pathway
CRP binds receptors on what types of cells? correct answers neutrophils, monocytes,
and macrophages and promotes phagocytosis
CRP main function correct answers most widely used marker of acute inflammation
How many hours after infection, surgery, or physical trauma to the body, is there a rapid
increase of CRP? correct answers 4-6 hours; can be up to a 100-1000-fold increase
and levels peak within 24-72 hours
CRP common markers of inflammation correct answers - pain
- heat
- redness
- swelling (Edema)
What conditions are associated with elevated levels of CRP? correct answers - heart
disease and myocardial infarction (heart attack)
- bacterial & viral infections
- TB
- autoimmune diseases - RA and SLE
- Collagen diseases - Scleroderma
- Malignant diseases (cancer)
What is the type of serological technique used in today's lab? correct answers latex
agglutination; latex particle coated with anti-CRP
Is the lab performed today quantitative or qualitative? correct answers qualitative
What does CRP stand for? correct answers C-reactive protein
CRP consists of how many identical subunits? //
What type of bonds hold it together? correct answers 5 identical subunits held together
by non-covalent bonds
Where is CRP synthesized? correct answers liver
CRP has actions similar to that of an antibody, what are its actions? correct answers
trace constituent of serum; originally thought to be an antibody to the c-polysaccharide
of pneumococci
- actions: opsonization, agglutination, precipitation, activation of complement by
classical pathway
CRP binds receptors on what types of cells? correct answers neutrophils, monocytes,
and macrophages and promotes phagocytosis
CRP main function correct answers most widely used marker of acute inflammation
How many hours after infection, surgery, or physical trauma to the body, is there a rapid
increase of CRP? correct answers 4-6 hours; can be up to a 100-1000-fold increase
and levels peak within 24-72 hours
CRP common markers of inflammation correct answers - pain
- heat
- redness
- swelling (Edema)
What conditions are associated with elevated levels of CRP? correct answers - heart
disease and myocardial infarction (heart attack)
- bacterial & viral infections
- TB
- autoimmune diseases - RA and SLE
- Collagen diseases - Scleroderma
- Malignant diseases (cancer)
What is the type of serological technique used in today's lab? correct answers latex
agglutination; latex particle coated with anti-CRP
Is the lab performed today quantitative or qualitative? correct answers qualitative
