NBME CBSE ACTUAL TEST QUIZ BANK 2024/2025| REAL EXAM QUESTIONS AND 100% CORRECT DETAILED ANSWERS (USMLE STEP 1) MEDICAL EXAMINATION

NBME CBSE ACTUAL i i




TEST QUESTION
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BANK QUESTIONS
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AND ANSWERS
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LATEST UPDATED
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i 2024-2025 GRADED A+ i i

,NBME CBSE ACTUAL TEST QUESTIONS i i i i



ANDANSWERS 2024-2025 COMPLETE
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62 year old woman - osteoporosis - a bisphosphonate is prescribed. The expected
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i beneficial effect of the drug is due to which of the following? -Answer= Decreased
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i Osteoclast Activity i




Cohot Study of elderly women - relative risk ratio for hip fractures among
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i thosewho exercise regularly is 1.2 (95% confidence interval of 1.1 to 1.8). Which of
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i the following is the conclusion about the effect of exercise on the risk of hip
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i fracture? -Answer= Statistically Significant Overall Increase Risk
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52 year old man goes to ER with chest pain radiating to his jaw while
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i shoveling snow. Pulse is 80/min and blood pressure is 130/70. Thei i i i i i i i i i




i mostimmediate treatment mechanism of action? - Answer= Increased
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i nitricoxide concentration
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24 year old woman - spilled hot grease on her left leg while working at a fast-
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food restaurant. Exam of leg shows 7cm pink, soft, granular, edematous
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i wound.The formation of this tissue was most likely caused by increased activity
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i of which? -Answer= a. Vascular Endothelial Growth Factor VEGF - stimulates
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i angiogenesiss.
TYPE III Collagen = Blood Vessels - early wound repair
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27 year old man- MVC - skull x-ray shows a linear, nondepressed basal skull
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i fracture - increased serum osm and decreased urin osm. Following
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i desmopressin urine osm increases. Desmopressin's effect is due to the i i i i i i i i i




i activationof which of the following? -Answer= a. Adenylyl Cyclase
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, Adenylate Cyclase - ATP - CAMP -
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-PROTEKINASE A -- Ca v2
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A 10 month old boy - 4 day history of fever and cough. He attends day care
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i center. Chest exam shows intercostal retractions along with bilateral, diffuse
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i wheezes and expiratory rhonchi. The infectious agent most likely has which of
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i thefollowing properties? -Answer= Mediation of Cell Entry via a fusion protein
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A 17 year old girl in ED - 15 minutes after being stung by a bee. Mild light
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i headedness but no difficulty swallowing- Bilateral wheezing - Which is
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i mostappropriate pharmacotherapy for this patient? -Answer= B2- Agonist
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14 year old boy - 2 day history of sore throat and fever that peaks in late
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i afternoon. 1 week of fatigue. He recentaly had sex with one partner. Physical
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i exam show cervical lymphadenopathy and pharyngeal erythema with a
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i creamyexudate. DX? -Answer= Infectious Mononucleosis
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, 57 year old man - radiation therapy for squamous cell carcinoma of the lung.
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i Despite therapy, tumor increases in size and he dies 6 months later. The
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i progressive tumor growth is due to a defect in cell cycle arrest in which of i i i i i i i i i i i i i i



i thefollowing phases of cell cycle? -Answer= G1
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28 year old - lived in sub-Saharan Africa - until he came to the US. Temp of 100.4
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- imaging shows bilateral hydroureter and hydronephrosis. Biopsy shows
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i markedfibrosis and scattered granulomas. DX? -Answer= Schistosomiasis
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A couple with a family history of a-thalassemia. Woman has one gene
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i deletionand man has two gene deletion. If the two gene is trans - what
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i percentage ofoffspring will have a two gene deletion? i i i i i i i i




-Answer= 50% i




previously healthy 40 year brought to emergency department by her husband
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- 2 day history of fever, lethargy, confusion. PE shows scattered petechiae
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i andecchymoses over the lower extremities - 3+ polychromasia and 3+
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i schistocytes and Low platelets Dx? -Answer= Thrombotic Thrombocytopenia i i i i i i i




i Purpura


16 year old boy - is admitted to the ER because of a knife wound to the left
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i sideof his chest. An X- ray of the chest shows an air-fluid level in the left
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i side of thechest, partial collapse of the left lung, and the elevation of the
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i stomach bubble. i




The mediastinum is midline. DX? -Answer= Hemopneumpothorax
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