NR507/ NR 507 Midterm Exam (Latest 2024/ 2025
Update) Advanced Pathophysiology | Complete Guide
with Questions and Verified Answers| 100% Correct |
Grade A – Chamberlain
Allergic contact dermatitis is an example of - ANSWER Type 4 hypersensitivity
reaction
Which of the following are considered the "first responders" of the innate immune system?
(Appear first in any immune response) - ANSWER Neutrophils
Hives (Urticaria) are an example of a - ANSWER Type 1 hypersensitivity reaction
Type 2 (cytotoxic) hypersensitivity reactions are mediated by: - ANSWER IgG or
IgM
Anaphylaxis is a - ANSWER Type 1 hypersensitivity reaction
,Type 1 hypersensitivity reactions are mediated by - ANSWER IgE and mast cells
Example of Type 1 hypersensitivity reaction - ANSWER Hay fever
Most dangerous form of Type 1 hypersensitivity reaction - ANSWER Anaphylactic
reaction systemic response causing hypotension and severe bronchoconstriction
Local symptoms of Type 1 hypersensitivity - ANSWER Itching, rash
Systemic symptoms of Type 1 hypersensitivity reaction - ANSWER Wheezing
Main treatment of anaphylaxis - ANSWER Epinephrine
,Example of Type 2 hypersensitivity reaction - ANSWER ABO incompatibility
Graves Disease (hyperthyroidism)
Primary effector cells involved in Type 2 hypersensitivity reactions - ANSWER
Macrophages
Type 2 hypersensitivity reactions - ANSWER -Tissue specific
-Can cause tissue damage or alter function
Type 4 hypersensitivity reactions are mediated by - ANSWER Caused by cytotoxic
T cells attacking tissue directly (no antibody)
Which of the following is the underlying pathology for hay fever? - ANSWER
Mast cell degranulation
Damage occurs with ABO incompatibility because - ANSWER Complement
damages RBC membrane causing RBC lysis
, Which of the following assessment findings would be expected in a patient who presents with
urticaria? - ANSWER Eosinophilia
Example of Type 4 hypersensitivity reaction - ANSWER Contact dermatitis (poison
ivy, metal allergy)
Type 3 hypersensitivity reactions - ANSWER - Are NOT organ specific
- antigen-antibody complex deposited in tissues
Type 3 hypersensitivity reaction examples - ANSWER Rheumatoid Arthritis
Systemic Lupus Erythematous (SLE)
Scope of Damage of SLE - ANSWER - Facial rash confined to the cheeks (malar
rash)
- Discoid rash (raised patches, scaling)
- photosensitivity (development of skin rash as a results of sunlight exposure)
- oral or nasopharyngeal ulcers
Update) Advanced Pathophysiology | Complete Guide
with Questions and Verified Answers| 100% Correct |
Grade A – Chamberlain
Allergic contact dermatitis is an example of - ANSWER Type 4 hypersensitivity
reaction
Which of the following are considered the "first responders" of the innate immune system?
(Appear first in any immune response) - ANSWER Neutrophils
Hives (Urticaria) are an example of a - ANSWER Type 1 hypersensitivity reaction
Type 2 (cytotoxic) hypersensitivity reactions are mediated by: - ANSWER IgG or
IgM
Anaphylaxis is a - ANSWER Type 1 hypersensitivity reaction
,Type 1 hypersensitivity reactions are mediated by - ANSWER IgE and mast cells
Example of Type 1 hypersensitivity reaction - ANSWER Hay fever
Most dangerous form of Type 1 hypersensitivity reaction - ANSWER Anaphylactic
reaction systemic response causing hypotension and severe bronchoconstriction
Local symptoms of Type 1 hypersensitivity - ANSWER Itching, rash
Systemic symptoms of Type 1 hypersensitivity reaction - ANSWER Wheezing
Main treatment of anaphylaxis - ANSWER Epinephrine
,Example of Type 2 hypersensitivity reaction - ANSWER ABO incompatibility
Graves Disease (hyperthyroidism)
Primary effector cells involved in Type 2 hypersensitivity reactions - ANSWER
Macrophages
Type 2 hypersensitivity reactions - ANSWER -Tissue specific
-Can cause tissue damage or alter function
Type 4 hypersensitivity reactions are mediated by - ANSWER Caused by cytotoxic
T cells attacking tissue directly (no antibody)
Which of the following is the underlying pathology for hay fever? - ANSWER
Mast cell degranulation
Damage occurs with ABO incompatibility because - ANSWER Complement
damages RBC membrane causing RBC lysis
, Which of the following assessment findings would be expected in a patient who presents with
urticaria? - ANSWER Eosinophilia
Example of Type 4 hypersensitivity reaction - ANSWER Contact dermatitis (poison
ivy, metal allergy)
Type 3 hypersensitivity reactions - ANSWER - Are NOT organ specific
- antigen-antibody complex deposited in tissues
Type 3 hypersensitivity reaction examples - ANSWER Rheumatoid Arthritis
Systemic Lupus Erythematous (SLE)
Scope of Damage of SLE - ANSWER - Facial rash confined to the cheeks (malar
rash)
- Discoid rash (raised patches, scaling)
- photosensitivity (development of skin rash as a results of sunlight exposure)
- oral or nasopharyngeal ulcers
