Exam 2: Pharmacotherapeutics for Advanced Practice Nurse Practitioner Questions with Answers. What are commonly used abortive therapies for a headache? – cor rect answers-OTC analgesics -Ergot Derivatives -Triptans -Antiemetics Which OTC analgesics are r

Exam 2: Pharmacotherapeutics for Advanced Practice Nurse Practitioner Questions with Answers. What are commonly used abortive therapies for a headache? – cor rect answers-OTC analgesics -Ergot Derivatives -Triptans -Antiemetics Which OTC analgesics are recommended for management of headaches? - correct answers-Aspirin -Tylenol -Ibuprofen -Naproxen -Excedrin Migraine -Advil Migraine How does aspirin play a role in management of HA? - correct answers-anti-prostaglandin -antiplatelet -serotonergic activity How do NSAIDs play a role in management of HA? - correct answersinhibits prostaglandin synthesis for central analgesia effects How do ergot derivatives help manage HA? - correct answersVasoconstriction to decrease pulsation in extra cranial arteries without reducing cerebral blood flow What are some factors that prevent a provider from prescribing Ergotamine? - correct answers-Extreme nausea & vomiting -Unpredictable oral absorption How many doses per week of Ergotamine can be used? Per month? - correct answers-2/week -12/month Ergotamine is contraindicated in which patients? - correct answersPregnant & children Why might dihydroergotamine (DHE) be prescribed over Ergotamine and who might be a better candidate for it? - correct answersLess vasoconstrictive effects *May be better alternative for patients with peripheral vascular disease How do triptans influence HA pain? - correct answersvasoconstriction & blockage of pain pathways to brainstem Why would a provider prescribe a different triptan if one is not effective? - correct answersThey each have slightly different onsets & 1/2 lives