Advanced Pharmacology for Care of the Family
Expected Questions and Verified Answers
1. Why do men have higher hematocrit levels than women?
Ans>> They produce more
testosterone which results in higher amounts of erythropoietin and erythrocytes.
2. What is the Black Box warning for the androgen Oxandrolone?
Ans>> Can cause peliosis hepatitis; blood-filled cysts form in the liver leading to failure or
intrabdominal hemorrhage
3. What are the disorders that the androgen testosterone can treat?
Ans>> Hypogo- nadism (male), replacement therapy
,4. What are the disorders that the androgen methyltestosterone can treat?
Ans>> -
Replacement and hypogonadism in males
5. What are the disorders that the androgen oxandrolone can treat?
Ans>> Catabolic states (cachexia)
6. Testosterone can be used to treat what symptoms in post-menopausal women?
Ans>> Reduced genital sensitivity, fatigue, and decreased libido
7. What hormones does androgens suppress?
Ans>> Luteinizing and follicle-stimulat- ing
,8. Which particle in the life cycle of chlamydia trachomatis is considered
infectious and first infects the host cell?
Ans>> elementary body
9. What is the recommended testing for males suspected to have Chlamydia?-
Ans>> first-catch urine for nucleic acid amplification test (NAAT)
10. What are the CDC screening recommendations for chlamydia in asympto- matic
females?
Ans>> annual screening annually in sexually active females 24 years or younger.
11. What is the recommend treatment for uncomplicated chlamydia in
non-pregnant females and males?
Ans>> doxycycline 100mg by mouth twice daily x7 days (alternate azithromycin 1g by mouth
x1)
, 12. What is the mechanism of action of donepezil (Aricept)?
Ans>> inhibits centrally active acetylcholinesterase
13. What are the common side effects of Aricept?
Ans>> gastrointestinal symptoms (nausea and diarrhea), headache, dizziness, muscle
weakness
14. List the precautions for Aricept?
Ans>> sick sinus syndrome and seizure disorder
15. When combined with and peripheral side effects
and rate of elimination can be increased for Aricept?
Ans>> CYP2D6 & CYP3A4
16. What is the mechanism of action of Rivastigmine (Exelon)?