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LECTURE PRESENTATIONS FOR CAMPBELL BIOLOGY, 9TH EDITION JANE B. REECE, LISA A. URRY, MICHAEL L. CAIN, STEVEN A. WASSERMAN, PETER V. MINORSKY, ROBERT B. JACKSON

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CAMPBELL BIOLOGY, 9TH EDITION JANE B. REECE, LISA A. URRY, MICHAEL L. CAIN, STEVEN A. WASSERMAN, PETER V. MINORSKY, ROBERT B. JACKSON

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LECTURE PRESENTATIONS
For CAMPBELL BIOLOGY, NINTH EDITION
Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson



Chapter 5

The Structure and Function of
Large Biological Molecules



Lectures by
Erin Barley
Kathleen Fitzpatrick
1

© 2011 Pearson Education, Inc.

,Overview: The Molecules of Life
• All living things are made up of four classes
of large biological molecules:
– carbohydrates,
– lipids,
– proteins, and
– nucleic acids
• Macromolecules
• are large molecules
• composed of thousands of covalently connected atoms
– Concept 2.3 ( for more information)
» A covalent bond is the sharing of a pair of valence
electrons by two atoms

2
© 2011 Pearson Education, Inc.

,Concept 5.1:
Macromolecules are polymers, built
from monomers




3

, • A polymer is
• a long molecule
• consisting of many similar building blocks
• These small building-block molecules are called
monomers


• Three of the four classes of lifeʼs organic
molecules are polymers
– Carbohydrates
– Proteins
– Nucleic acids 4
© 2011 Pearson Education, Inc.

,The Synthesis and Breakdown of Polymers
• Synthesis of polymer from monomers:
– By dehydration reaction
• when two monomers bond together ???
– through the loss of a water molecule




5
© 2011 Pearson Education, Inc.

,Figure 5.2a



(a) Dehydration reaction: synthesizing a polymer

1 2 3

Short polymer Unlinked monomer

Dehydration removes
a water molecule,
forming a new bond.



1 2 3 4

Longer polymer
6

,• Breakdown of Polymers to monomers :
– By hydrolysis reaction
• the reverse of the dehydration reaction ??
– ----------------------------------------




7

,Figure 5.2b




(b) Hydrolysis: breaking down a polymer

1 2 3 4



Hydrolysis adds
a water molecule,
breaking a bond.




1 2 3


8

,The Diversity of Polymers
• Each cell has thousands of different
macromolecules
HO




• Macromolecules vary among
– cells of an organism,
– vary more within a species,
– and vary even more between species


• An immense variety of polymers can be built
from a small set of monomers

9
© 2011 Pearson Education, Inc.

, Concept 5.2:
Carbohydrates serve as fuel and
building material




10

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