Minimising Pain & Distress-
How is "pain and distress" defined in regard to laboratory animal
research? - CORRECT ANSWER-Pain - an unpleasant sensation and
emotional experience.
Distress - a state in which an animal is unable to adapt to one or more
stressors.
What factors can be associated with animal pain and distress? -
CORRECT ANSWER-body temperature
respiration
hypoxia
edema
blood electrolytes
housing environment - caging, cage mates, lighting, humidity, noise,
vibration, environmental temperature
dehydration
weight loss
,experimentally induced injury/disease
How can pain and distress be recognized in laboratory animals? -
CORRECT ANSWER-clinical signs of distress - HR, Temp, RR, etc.
behavioral signs of distress - hunched back, hair poking up,
How can the research environment lead to distress in laboratory
animals? - CORRECT ANSWER-caging, cage mates, lighting, humidity,
noise, vibration, environmental temperature
In what ways can pain and distress be minimized or eliminated? -
CORRECT ANSWER-Considering any procedure that would be
considered painful or distressing in a human to be painful or distressing
in an animal.
Considering all potential source of pain and distress both for individual
components and cumulatively across the course of the pre-, intra-, and
post-procedural period.
Identifying opportunities for refinement in experimental technique.
Pre-emptively planning for judicious use of anesthetics and analgesics
based upon.
, Refining experimental techniques.
Implementing data driven best practices.
Engaging in appropriate monitoring, interventions, and implementation of
humane endpoints.
How do federal regulations address animal pain and distress in
research? - CORRECT ANSWER-Animal pain and distress must be
avoided or minimized when consistent with sound scientific practices.
Which of the following factors may cause or contribute to animal pain
and distress related to a research procedure?
surgical wounds
hypothermia
dehydration
all of the above - CORRECT ANSWER-all of the above
Monitoring animals after a procedure is beneficial for:
complying with regulatory mandates on welfare for research animals
How is "pain and distress" defined in regard to laboratory animal
research? - CORRECT ANSWER-Pain - an unpleasant sensation and
emotional experience.
Distress - a state in which an animal is unable to adapt to one or more
stressors.
What factors can be associated with animal pain and distress? -
CORRECT ANSWER-body temperature
respiration
hypoxia
edema
blood electrolytes
housing environment - caging, cage mates, lighting, humidity, noise,
vibration, environmental temperature
dehydration
weight loss
,experimentally induced injury/disease
How can pain and distress be recognized in laboratory animals? -
CORRECT ANSWER-clinical signs of distress - HR, Temp, RR, etc.
behavioral signs of distress - hunched back, hair poking up,
How can the research environment lead to distress in laboratory
animals? - CORRECT ANSWER-caging, cage mates, lighting, humidity,
noise, vibration, environmental temperature
In what ways can pain and distress be minimized or eliminated? -
CORRECT ANSWER-Considering any procedure that would be
considered painful or distressing in a human to be painful or distressing
in an animal.
Considering all potential source of pain and distress both for individual
components and cumulatively across the course of the pre-, intra-, and
post-procedural period.
Identifying opportunities for refinement in experimental technique.
Pre-emptively planning for judicious use of anesthetics and analgesics
based upon.
, Refining experimental techniques.
Implementing data driven best practices.
Engaging in appropriate monitoring, interventions, and implementation of
humane endpoints.
How do federal regulations address animal pain and distress in
research? - CORRECT ANSWER-Animal pain and distress must be
avoided or minimized when consistent with sound scientific practices.
Which of the following factors may cause or contribute to animal pain
and distress related to a research procedure?
surgical wounds
hypothermia
dehydration
all of the above - CORRECT ANSWER-all of the above
Monitoring animals after a procedure is beneficial for:
complying with regulatory mandates on welfare for research animals
