NAMS Certification Exam 2022
Early Menopause
FMP before age 45
Late Menopause
FMP after age 54
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Bilateral oophorectomy prior to age 45 increases risks for:
- All cause mortality
- Coronary heart disease
- CVD
- Menopause symptoms
- Worsening mood symptoms
- Higher incidence of Parkinson Disease
- Associated with cognitive impairment
Early Menopause Transition (-2)
7 or more days persistent difference in cycle length from previous normal cycle
- Results of increased follicular aging and depletion
- Inhibin B decreases
- FSH increases (Variable)
LOOP Cycles
, Explains elevation of Estradiol in perimenopause
- Rising FSH levels recruit 2nd follicle during luteal phase which leads to overproduction of
Estradiol
- This causes menstrual changes in future cycles
Decreased AMH in Early Menopause Transition
More frequent anovulatory cycles
Decreased Inhibin B in Early Menopause Transition
- Skipped menstrual cycles
- Mastalgia
- Migraine
- Menorrhagia (with LOOP cycles)
- Endometrial Hyperplasia
Late Menopause Transition (-1)
60 or more days of amenorrhea for women aged 45 years or older
- Women 40-44 years with recurrent episodes of amenorrhea of 60 day for longer within a year
improves prediction of entry into late menopause transition
Late Menopause Transition (-1) Duration
1-3 years
Late Menopause Transition (-1) Symptoms
VMS likely
STRAW Stage where FSH > 25
Late Menopause Transition (-1)
Elevated FSH symptoms in Late Menopause Transition
- VMS
- Sleep disturbance
- Changes in weight distribution
- Increased variability in cycle length
Decreased Inhibin B in Late Menopause Transition
Early Menopause
FMP before age 45
Late Menopause
FMP after age 54
Previous
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Next
Rewind 10 seconds
Move forward 10 seconds
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0:02
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0:15
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Brainpower
Read More
Bilateral oophorectomy prior to age 45 increases risks for:
- All cause mortality
- Coronary heart disease
- CVD
- Menopause symptoms
- Worsening mood symptoms
- Higher incidence of Parkinson Disease
- Associated with cognitive impairment
Early Menopause Transition (-2)
7 or more days persistent difference in cycle length from previous normal cycle
- Results of increased follicular aging and depletion
- Inhibin B decreases
- FSH increases (Variable)
LOOP Cycles
, Explains elevation of Estradiol in perimenopause
- Rising FSH levels recruit 2nd follicle during luteal phase which leads to overproduction of
Estradiol
- This causes menstrual changes in future cycles
Decreased AMH in Early Menopause Transition
More frequent anovulatory cycles
Decreased Inhibin B in Early Menopause Transition
- Skipped menstrual cycles
- Mastalgia
- Migraine
- Menorrhagia (with LOOP cycles)
- Endometrial Hyperplasia
Late Menopause Transition (-1)
60 or more days of amenorrhea for women aged 45 years or older
- Women 40-44 years with recurrent episodes of amenorrhea of 60 day for longer within a year
improves prediction of entry into late menopause transition
Late Menopause Transition (-1) Duration
1-3 years
Late Menopause Transition (-1) Symptoms
VMS likely
STRAW Stage where FSH > 25
Late Menopause Transition (-1)
Elevated FSH symptoms in Late Menopause Transition
- VMS
- Sleep disturbance
- Changes in weight distribution
- Increased variability in cycle length
Decreased Inhibin B in Late Menopause Transition
