NRNP 6566 WK1-5 Midterm Exam - Questions with Correct Answers/ Expert Verified/Already Grade A+/ Latest Version 2024/2025

Describe cytochrome p450 system - Answer Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - Answer block metabolic activity from one or more CYP450 enzymes Inducers - Answer increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - Answer Albumin is the plasma protein with the greatest capacity for binding drugs. Binding plasma proteins affect drug distribution into tissues, because only drug that is not bound is available to penetrate tissues, bind to receptors, and exert activity. As free drug leaves the blood stream, more bound drug is released from binding sites. Low albumin levels - Answer malnutrition, chronic illness