Respiratory Pharmacology Chapter 8 Latest Update Already Passed

Respiratory Pharmacology Chapter 8 Latest Update Already Passed This is a cardiac stimulant and caffiene is this also Xanthine Clinical uses for xanthine are asthma, COPD, and apnea of prematurity (neonates) what is used for asthma as a maintenance therapy that is not used in children? Theophylline Why is Theophylline not used in children? There is a narrow therapuetic index, which means it borders on the chance of being toxic Clinical indications for Apnea of Prematurity First line of treatment Theophylline is mostly used, but caffeine is a better choice Specific Xanthine agent is known as? Methylxanthine what effects on humans can xanthines have? CNS stimulation cardiac muscle stimulation diuresis smooth muscle relaxation cerebral vasoconstriction (used for headaches) peripheral and coronary vasodilation Proposed theories of activities of the exact mechanism is known. True or False False, it is unknown what is the chemical that deactivates the bronchodilators? phosphodiesterase what is the therapeutic range for titrating Theophylline doses? Normal serum levels are -10 to 20 ug/ml which increases how much the heart has to pump, a vasoconstrictor or a vasodilator? vasodilator what condition effects Theophylline activity? the kidney and liver name two things that will increase the Theophylline level. left ventricular failure viral hepatitis Nonbronchodilator effects of Theoplhylline are? Cardio effects (increase cardio output, decrease pulmonary vascular resistance) increase in respiratory muscle endurance increase in ventilatory drive Why is there an increase in ventilatory drive with Theophylline? It is a CNS stimulator This is a nitrogenous compound found in many organs and in the blood and urine Xanthine What is the name of the chemical group of drugs derived from xanthines? methylxanthines Name three methylated xanthines caffeine, theophylline,