Family Medicine EOR: Obstetrics and Gynecology (Smarty PANCE) Exam Questions and Answers 100% Correct | Latest Version

Family Medicine EOR: Obstetrics and Gynecology (Smarty PANCE) Exam Questions and Answers 100% Correct | Latest Version What is the incidence of breast cancer? 12% Lifetime Risk Percentage of women with breast cancer who have zero known risk factors? 75% Percentage of all breast cancers in women <30 years? ~2% Percentage of all breast cancers in women >70 years? 33% Percentage of breast cancers due to inherited mutations? 10% Approximate percentage of inherited breast cancers due to BRCA 1/2? ~50% (5% of all breast cancers) What is the expected ER status of BRCA 1 vs BRCA 2 breast cancers? BRCA 1 ER negative (~70%) BRCA 2 ER positive (~70%) Name some breast cancer susceptibility genes BRCA 1/2 Tp53 (Li Fraumeni) PTEN STK11 (Peutz-Jeghers) PTALB CDH1 How do you decrease breast cancer risk in women with BRCA mutations? Prophylactic bilateral mastectomy (90% risk reduction) +prophylactic BSO -> 95% risk reduction Rule o' Thumb: 5 years before the earliest onset of cancer in mom What is the preferred screening for mutation carriers? MRI annually Most common motivation for medicological cases of the breast Failure to diagnose a breast carcinoma Triad of Error for misdiagnosis of breast cancer 1) Age <45 years 2) Self-diagnosed mass 3) Negative mammogram Hx breast cancer risk factors? NAACP Nulliparity Age at menarche (<13 yrs) Age at menopause (>55 yrs) Breast cancer (self, family) Pregnancy of 1st child >30yrs Physical breast cancer risk factors? CHAFED LIPS Cancer in breast (3% synchronous contralat) Hyperplasia (2x) Atypical hyperplasia (4x) Female (100x) Elderly DCIS LCIS Inherited gene