Test Bank For Tietz Fundamentals Of Clinical Chemistry

A "subject-based" reference value is: a. obtained from a group of systematically defined reference individuals. b. the type of value referred to when the term reference value is used with no qualifying words. c. based on several samples collected over time in a single individual. d. a random sample of all individuals in the parent population who fulfill the selection criteria. - CORRECT ANSWERS-Answer: a. obtained from a group of systematically defined reference individuals. 1. A nonspecific response to inflammation that includes elevation of certain plasma proteins and decrease of others due to cytokine production is referred to as a(n): a. Cytokine response. b. Acute-phase response. c. Reduction reaction. d. Allergic reaction. - CORRECT ANSWERS-Answer: b. Acute-phase response. 1. Are the results obtained from a point-of-care test (POC) device qualitative, quantitative, or semi-quantitative, or can they be all of these? a. Qualitative only b. Quantitative only c. Semi-quantitative only d. All of the above result types can be obtained from a point-of-care test device. - CORRECT ANSWERS-Answer: d. All of the above result types can be obtained from a point-of-care test device. 1. Ion-selective electrodes measure electrical potential difference across a membrane using the principles of: a. Coulometry. b. Potentiometry. c. Amperometry. d. Conductivity. - CORRECT ANSWERSAnswer: b. Potentiometry. 1. Meta-analysis: a. is a statistical technique that compares results from various studies. b. is an extensive and explicit strategy that is used to find all studies (published or unpublished) pertaining to a single assay. c. includes the quality and the quantity of the health outcome. d. is a tool used to facilitate implementation of lessons from primary studies and systematic reviews. - CORRECT ANSWERS-Answer: b. is an extensive and explicit strategy that is used to find all studies (published or unpublished) pertaining to a single assay. 1. One aspect of universal precautions and an OSHA requirement involves the provision of personal protective equipment (PPE) to laboratory employees. PPE includes (but is not limited to) which of the following? a. Gloves only. b. Gloves and a lab coat only. c. Gloves, eye protection, and a lab coat. d. Gloves, eye protection, a lab coat, and special footwear. - CORRECT ANSWERS-Answer: c. Gloves, eye protection, and a lab coat. 1. Protein tumor markers found both in normal fetal tissue and in certain tumors are referred to as: a. Embryonic proteins. b. Tumor-associated antigens. c. Oncogenes. d. Oncofetal antigens. - CORRECT ANSWERS-Answer: d. Oncofetal antigens. 1. The clinical laboratory discipline that is used most often to assess inherited disease through the study of the constitutive genome is: a. transfusion services. b. clinical chemistry. c. molecular diagnostics. d. hematology. - CORRECT ANSWERS-Answer: c. molecular diagnostics. 1. The component of an immunoassay that determines the analytical sensitivity and specificity of the reaction is the: a. labeled antigen. b. antigen. c. immunochemical label. d. antibody. - CORRECT ANSWERS-Answer: d. antibody. 1. The enzyme that demonstrates the highest serum activity in intrahepatic biliary obstruction and is also elevated in primary liver neoplasm is: a. Alkaline phosphatase (ALP). b. Creatine kinase (CK). c. Amylase (AMY). d. γ-glutamyl transferase (GGT). - CORRECT ANSWERS-Answer: d. γ-glutamyl transferase (GGT). 1. The isoelectric point of an amino acid or protein is defined as the: a. Ability of the amino acid or protein to carry both positive and negative charges. b. pH at which the amino acid or protein has a negative charge. c. pH at which a molecule has no net charge. d. Point on an electrophoretic gel at which that specific protein migrates. - CORRECT ANSWERS-Answer: c. pH at which a molecule has no net charge. 1. The Michaelis-Menten constant is: a. Vmax. b. Km. c. 1/v. d. [S]. - CORRECT ANSWERS-Answer: b. Km. 1. The process by which simulated patient specimens made from a common pool are analyzed by laboratories to determine the "quality" of the laboratories' performance is referred to as: a. quality control. b. proficiency testing. c. total quality management. d. Youden plot. - CORRECT ANSWERS-Answer: b. proficiency testing. 1. The type of error that occurs when an analytical method is nonspecific for an analyte and is actually considered to be a type of bias is: a. systematic error. b. nonsystematic error. c. random error. d. true error. - CORRECT ANSWERS-Answer: a. systematic error. 1. To be analyzed by gas chromatography, a compound must: a. be volatile or be made volatile. b. not be volatile. c. be water-soluble. d. contain a nitrogen atom. - CORRECT ANSWERS-Answer: a. be volatile or be made volatile. 1. What units of measurement are traditionally applied when wavelengths in the electromagnetic spectrum are measured? a. Millimeters (mm) b. Centimeters (cm) c. Nanometers (nm) d. Micrometers (µm) - CORRECT ANSWERS-Answer: c. Nanometers (nm) 1. Which blood specimen, in a multi-draw situation, most closely represents the composition of circulating blood? a. The blood drawn first. b. The final tube drawn. c. Only the serum tubes. d. Only the plasma tubes. - CORRECT ANSWERS-Answer: a. The blood drawn first. 1. Which of the following classes of mass spectrometers involves ions making a single trip through the instrument and then striking a detector where they are destructively detected? a. Trapping type b. Beam type c. Mass-selective ejection type d. Ion-cyclotron resonance type - CORRECT ANSWERSAnswer: b. Beam type 1. Which type of specimen label has resulted in a reduction in preanalytical specimen identificatio