Exam 4: NSG555/ NSG 555 (Latest 2023/ 2024 Update) Nurse Practitioners in Primary Care II Exam| Questions and Verified Answers| 100% Correct| Grade A

Exam 4: NSG555/ NSG 555 (Latest 2023/ 2024 Update) Nurse Practitioners in Primary Care II Exam| Questions and Verified Answers| 100% Correct| Grade A Q: Posaconazole indications AIDS/immunocompromised patients ok! Asperigillis and Candida Mucormycosis Q: the only imidazole azol Answer: ketoconazole Q: azole that crosses BBB Answer: Fluconazole Q: Fluconazole metabolism vs others Answer: Fluconazole- CYP450-2C9 and 2C19 Others- 450 3A4, Q: Which azole is best for alprazolam and statin? Answer: non-3A4 substrate Fluconazole is the best! 2C9 and 2C19 Q: Fluconazole unique DDI Answer: Warfarin ->2C9 Codeine -> 2C9 activation (no pain relief) SSRI NSAID Celecoxib Q: ***MAJOR*** cause of Candida resistance Answer: Fluconazole parapsilosis albicans glabrata and krusei are also resistance Q: Fluconzole indications Answer: **YEAST** 1. Candidiasis- oropharyngeal and esophagel, overuse in vaginal is leading to resistance 2. Cryptococcosis **prophylaxis** 3. **Coccidoides- meningitis*** NOT for all other Thermally dimoprhic fungi ***NOT Aspergiosis** Q: Voriconazole indications Answer: Can be used for **invasive aspergillosis- mold!*** like fluconazole Can cross the BBB like fluconazole Q: Isavuconazomium sulfate Answer: Cresemba Q: Isavuconazomium sulfate indications Answer: *Invasive asperigillosis* **invastic mucormycosis** DDI via CYP3A4 Q: mycelex troche Answer: clotrimazole troche MUCOSOAL TREATMENT (not systemic) Q: squalene epoxidase inhibitor indications **Tinea only***