NR546 / NR 546 Final Exam (2024 / 2025 Updated!!): Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner | Complete Guide Questions and Verified Answers - Chamberlain

Final Exam: NR546 / NR 546 Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner Final Exam Review | Complete Guide Questions and Verified Answers | 2024 / 2025 Updated!! – Chamberlain Q: BPD I Answer: manic mood dominates characterized by mood swings from extremely high (mania) to extremely low (depression) Q: BPD II Answer: the presence or history of an MDD and at least one hypomanic episode. Symptoms last for at least 4 days but no longer than 7. Q: Cyclothenia Answer: Chronic presentation of hypomanic and depressive symptoms but does not meet diagnostic criteria for a major depressive episode or manic/hypomanic episode. Q: decreased positive affect Answer: Depressed mood, loss of joy, lack of interest, loss of energy, decreased alertness, decreased self-confidence, and appetite changes are symptoms of this affect Q: increased negative affect Answer: depressed mood, guilt, anxiety/fear, hostility, irritability, loneliness, and appetite changes are symptoms of this affect Q: Serotonin receptors Answer: 90% are in the GI tract, 10% are in the brain Q: SARI MOA Answer: block 5HT 2A and 2C receptors allowing more serotonin to interact at postsynaptic 5HT 1A Q: Most common SARI Answer: trazadone Q: Trazadone Answer: This antidepressant causes sedation, drowsiness, blurred vision, constipation, dry mouth, and priapism. Can also be used to treat insomnia and anxiety. Q: mirtazapine (remeron) Answer: Antidepressant that is a serotonin, NE, and alpha2 receptor AGONIST that is assoc w/ drowsiness/sedation (useful for pt with insomnia), and can cause increased appetite and weight gain (appropriate for pt who loses weight d/t depression). Q: Vilazodone (Viibryd) Answer: Antidepressant that is a serotonin multimodal (SMM)/serotonin partial agonist reuptake inhibitor (SPARI) that inhibits serotonin reuptake with partial 5HT-1A agonism and is appropriate for depression/comorbid anxiety. Its action is similar to a combo of SSRI and bus-irons. Q: Vortioxetine (Trintellix) Answer: SMM antidepressant that acts as SSRI plus 5HT-1A partial agonist and improves depression related cognition. Q: Monoamine hypothesis of depression Answer: depression occurs as a result of a deficiency of 1 or all 3 monoamine transmitters, while mania results from an excess.