PC707 Module 3-GI Exam 2024 ( Unit A: Peptic Ulcer and GE Reflux Unit B: Laxatives and Anti-Diarrheal Drugs Unit C: Chronic Constipation, Irritable Bowel Syndrome, and Inflammatory Bowel Disease Unit D: Antiemetic Drugs and Oral Ulcer Treatments)

PC707 Module 3-GI Exam 2024 ( Unit A: Peptic Ulcer and GE Reflux Unit B: Laxatives and Anti-Diarrheal Drugs Unit C: Chronic Constipation, Irritable Bowel Syndrome, and Inflammatory Bowel Disease Unit D: Antiemetic Drugs and Oral Ulcer Treatments) Antacids Examples - Answer ️️ -Calcium carbonate (Tums, Rolaids), Sodium bicarbonate (Alka Seltzer), Magnesium (Milk of Magnesia), Aluminum (Amphogel), Bismuth subsalicylate (Pepto-Bismol) Antacid Indications - Answer ️️ -Dyspepsia Acts immediately but weaker and short-lived Antacid MOA - Answer ️️ -Neutralize hydrochloric acid in the stomach, thereby increasing gastric pH above 4.0 Patient Teaching for Antacids - Answer ️️ -Be sure to separate antacids from other medications by 2 hours Avoid sodium bicarbonate in pregnancy for risk of fetal alkalosis and/or fluid overload Antacid Safety Concerns - Answer ️️ -Sodium bicarbonate may contribute to HTN Sodium-based antacids should be avoided in patients with cardiovascular disease Magnesium-containing antacids may cause diarrhea, contraindicated in renal insufficiency, may decrease absorption of warfarin (Coumadin) Bismuth subsalicylate contraindicated during pregnancy, lactation, in children <12 y/o H2RA Examples - Answer ️️ -Cimetidine (Tagamet), famotidine (Pepcid, Zantac 360), nizatidine (Axid) H2RA Indications - Answer ️️ -Gastric and duodenal ulcers